Search Results - "Bean, Andrew G."

ADAMTS5 Is a Critical Regulator of Virus-Specific T Cell Immunity by McMahon, Meagan, Ye, Siying, Izzard, Leonard, Dlugolenski, Daniel, Tripp, Ralph A, Bean, Andrew G D, McCulloch, Daniel R, Stambas, John

“…The extracellular matrix (ECM) provides physical scaffolding for cellular constituents and initiates biochemical and biomechanical cues that are required for…”
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MicroRNA Biomarkers for Infectious Diseases: From Basic Research to Biosensing by Tribolet, Leon, Kerr, Emily, Cowled, Christopher, Bean, Andrew G. D., Stewart, Cameron R., Dearnley, Megan, Farr, Ryan J.

“…In the pursuit of improved diagnostic tests for infectious diseases, several classes of molecules have been scrutinized as prospective biomarkers. Small (18–22…”
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Ferret Interferon (IFN)-Inducible Transmembrane Proteins Are Upregulated by both IFN-α and Influenza Virus Infection by Horman, William S J, Kedzierska, Katherine, Rootes, Christina L, Bean, Andrew G D, Nguyen, Thi H O, Layton, Daniel S

“…The current fears of a future influenza pandemic have resulted in an increased emphasis on the development and testing of novel therapeutic strategies against…”
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ILRUN Downregulates ACE2 Expression and Blocks Infection of Human Cells by SARS-CoV-2 by Tribolet, Leon, Alexander, Marina R, Brice, Aaron M, van Vuren, Petrus Jansen, Rootes, Christina L, Mara, Kostlend, McDonald, Meg, Bruce, Kerri L, Gough, Tamara J, Shi, Shuning, Cowled, Christopher, Bean, Andrew G D, Stewart, Cameron R

“…The human protein-coding gene (inflammation and lipid regulator with UBA-like and NBR1-like domains; previously C6orf106) was identified as a proviral factor…”
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Genome-wide siRNA Screening at Biosafety Level 4 Reveals a Crucial Role for Fibrillarin in Henipavirus Infection by Deffrasnes, Celine, Marsh, Glenn A, Foo, Chwan Hong, Rootes, Christina L, Gould, Cathryn M, Grusovin, Julian, Monaghan, Paul, Lo, Michael K, Tompkins, S Mark, Adams, Timothy E, Lowenthal, John W, Simpson, Kaylene J, Stewart, Cameron R, Bean, Andrew G D, Wang, Lin-Fa

“…Hendra and Nipah viruses (genus Henipavirus, family Paramyxoviridae) are highly pathogenic bat-borne viruses. The need for high biocontainment when studying…”
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Breaking the chain of zoonoses through biosecurity in livestock by Layton, Daniel S., Choudhary, Anupma, Bean, Andrew G.D.

“…Increases in global travel, trade and urbanisation are leading to greater incidence of zoonotic disease, and livestock are often a key link in the spread of…”
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Correction: ADAMTS5 Is a Critical Regulator of Virus-Specific T Cell Immunity by McMahon, Meagan, Ye, Siying, Izzard, Leonard, Dlugolenski, Daniel, Tripp, Ralph A, Bean, Andrew G. D, McCulloch, Daniel R, Stambas, John

“…Cleavage of versican by ADAMTS5 removes the ECM blockade, allowing migration (top panel). [...]versican accumulation in the absence of ADAMTS enzyme activity…”
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Characterization of chicken Mda5 activity: regulation of IFN-β in the absence of RIG-I functionality by Karpala, Adam J, Stewart, Cameron, McKay, Jim, Lowenthal, John W, Bean, Andrew G D

“…In mammals, Mda5 and RIG-I are members of the evolutionary conserved RIG-like helicase family that play critical roles in the outcome of RNA virus infections…”
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TNF Regulates Chemokine Induction Essential for Cell Recruitment, Granuloma Formation, and Clearance of Mycobacterial Infection by Roach, Daniel R, Bean, Andrew G. D, Demangel, Caroline, France, Malcolm P, Briscoe, Helen, Britton, Warwick J

“…Host immunity to mycobacterial infection is dependent on the activation of T lymphocytes and their recruitment with monocytes to form granulomas. These…”
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Prebiotics modulate immune responses in the gut-associated lymphoid tissue of chickens by Janardhana, Vijaya, Broadway, Mary M, Bruce, Matthew P, Lowenthal, John W, Geier, Mark S, Hughes, Robert J, Bean, Andrew G D

“…The recent European Union ban on the prophylactic use of in-feed antibiotics has escalated the search for alternatives for use within the poultry industry…”
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Dual microRNA Screens Reveal That the Immune-Responsive miR-181 Promotes Henipavirus Entry and Cell-Cell Fusion by Foo, Chwan Hong, Rootes, Christina L, Cowley, Karla, Marsh, Glenn A, Gould, Cathryn M, Deffrasnes, Celine, Cowled, Christopher J, Klein, Reuben, Riddell, Sarah J, Middleton, Deborah, Simpson, Kaylene J, Wang, Lin-Fa, Bean, Andrew G D, Stewart, Cameron R

“…Hendra and Nipah viruses (family Paramyxoviridae, genus Henipavirus) are bat-borne viruses that cause fatal disease in humans and a range of other mammalian…”
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Studying immunity to zoonotic diseases in the natural host — keeping it real by Bean, Andrew G. D., Baker, Michelle L., Stewart, Cameron R., Cowled, Christopher, Deffrasnes, Celine, Wang, Lin-Fa, Lowenthal, John W.

“…Key Points Zoonotic viruses pose a serious threat to human and animal health. Studying the immune response to zoonotic pathogens in the natural reservoir…”
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Increased inducible nitric oxide synthase expression in organs is associated with a higher severity of H5N1 influenza virus infection by Burggraaf, Simon, Bingham, John, Payne, Jean, Kimpton, Wayne G, Lowenthal, John W, Bean, Andrew G D

“…The mechanisms of disease severity caused by H5N1 influenza virus infection remain somewhat unclear. Studies have indicated that a high viral load and an…”
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Ribosome-Profiling Reveals Restricted Post Transcriptional Expression of Antiviral Cytokines and Transcription Factors during SARS-CoV-2 Infection by Alexander, Marina R, Brice, Aaron M, Jansen van Vuren, Petrus, Rootes, Christina L, Tribolet, Leon, Cowled, Christopher, Bean, Andrew G D, Stewart, Cameron R

“…The global COVID-19 pandemic caused by SARS-CoV-2 has resulted in over 2.2 million deaths. Disease outcomes range from asymptomatic to severe with, so far,…”
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Promotion of Hendra Virus Replication by MicroRNA 146a by Stewart, Cameron R, Marsh, Glenn A, Jenkins, Kristie A, Gantier, Michael P, Tizard, Mark L, Middleton, Deborah, Lowenthal, John W, Haining, Jessica, Izzard, Leonard, Gough, Tamara J, Deffrasnes, Celine, Stambas, John, Robinson, Rachel, Heine, Hans G, Pallister, Jackie A, Foord, Adam J, Bean, Andrew G, Wang, Lin-Fa

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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The Drivers of Pathology in Zoonotic Avian Influenza: The Interplay Between Host and Pathogen by Horman, William S J, Nguyen, Thi H O, Kedzierska, Katherine, Bean, Andrew G D, Layton, Daniel S

“…The emergence of zoonotic strains of avian influenza (AI) that cause high rates of mortality in people has caused significant global concern, with a looming…”
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Characterisation of chicken viperin by Goossens, Kate E., Karpala, Adam J., Rohringer, Andreas, Ward, Alistair, Bean, Andrew G.D.

“…•Molecular cloning and bioinformatic analysis of chicken viperin shows high similarity to other species.•Chicken viperin contains structural motifs similar to…”
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Immunostimulatory motifs enhance antiviral siRNAs targeting highly pathogenic avian influenza H5N1 by Stewart, Cameron R, Karpala, Adam J, Lowther, Sue, Lowenthal, John W, Bean, Andrew G

“…Highly pathogenic avian influenza (HPAI) H5N1 virus is endemic in many regions around the world and remains a significant pandemic threat. To date H5N1 has…”
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Circulating microRNA profiles of Hendra virus infection in horses by Cowled, Christopher, Foo, Chwan-Hong, Deffrasnes, Celine, Rootes, Christina L., Williams, David T., Middleton, Deborah, Wang, Lin-Fa, Bean, Andrew G. D., Stewart, Cameron R.

“…Hendra virus (HeV) is an emerging zoonotic pathogen harbored by Australian mainland flying foxes. HeV infection can cause lethal disease in humans and horses,…”
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Characterisation of chicken ZAP by Goossens, Kate E., Karpala, Adam J., Ward, Alistair, Bean, Andrew G.D.

“…•Molecular cloning and bioinformatic analysis of chicken ZAP shows high similarity to other avian species.•Chicken ZAP contains structural motifs similar to…”
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