Search Results - "Beamer, Celine A."

Environmental Immunology: Lessons Learned from Exposure to a Select Panel of Immunotoxicants by Kreitinger, Joanna M, Beamer, Celine A, Shepherd, David M

“…Exposure to environmental contaminants can produce profound effects on the immune system. Many classes of xenobiotics can significantly suppress or enhance…”
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Targeted deletion of the aryl hydrocarbon receptor in dendritic cells prevents thymic atrophy in response to dioxin by Beamer, Celine A., Kreitinger, Joanna M., Cole, Shelby L., Shepherd, David M.

“…In nearly every species examined, administration of the persistent environmental pollutant, 2,3,7,8-tetrachlorodibenzo- p -dioxin (dioxin, TCDD) causes…”
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Innate immune processes are sufficient for driving silicosis in mice by Beamer, Celine A., Migliaccio, Christopher T., Jessop, Forrest, Trapkus, Melanie, Yuan, Dorothy, Holian, Andrij

“…Although silica‐induced fibrosis and inflammation occurs independently of T, B, NK T, and NK cells, lymphocytes regulate inflammation via modulation of the…”
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Critical Role of MARCO in Crystalline Silica–Induced Pulmonary Inflammation by Thakur, Sheetal A., Beamer, Celine A., Migliaccio, Christopher T., Holian, Andrij

“…Chronic exposure to crystalline silica can lead to the development of silicosis, an irreversible, inflammatory and fibrotic pulmonary disease. Although,…”
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Scavenger receptor class A type I/II (CD204) null mice fail to develop fibrosis following silica exposure by Beamer, Celine A, Holian, Andrij

“…Alveolar macrophages express the class A scavenger receptor (CD204) (Babaev VR, Gleaves LA, Carter KJ, Suzuki H, Kodama T, Fazio S, and Linton MF. Arterioscler…”
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Nanoparticle-Induced Airway Eosinophilia Is Independent of ILC2 Signaling but Associated With Sex Differences in Macrophage Phenotype Development by Ray, Jessica L, Shaw, Pam K, Postma, Britten, Beamer, Celine A, Holian, Andrij

“…The majority of lung diseases occur with a sex bias in terms of prevalence and/or severity. Previous studies demonstrated that, compared with males, female…”
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Role of the aryl hydrocarbon receptor (AhR) in lung inflammation by Beamer, Celine A., Shepherd, David M.

“…Millions of individuals worldwide are afflicted with acute and chronic respiratory diseases, causing temporary and permanent disabilities and even death…”
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Motheaten (me/me) mice deficient in SHP-1 are less susceptible to focal cerebral ischemia by Beamer, Celine A., Brooks, Diane M., Lurie, Diana I.

“…We have demonstrated previously that the protein tyrosine phosphatase SHP‐1 seems to play a role in glial development and is upregulated in non‐dividing…”
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IL-1R signalling is critical for regulation of multi-walled carbon nanotubes-induced acute lung inflammation in C57Bl/6 mice by Girtsman, Teri Alyn, Beamer, Celine A, Wu, Nianqiang, Buford, Mary, Holian, Andrij

“…Abstract Exposure to certain engineered nanomaterials has been associated with pathological changes in animal models raising concerns about potential human…”
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Aryl hydrocarbon receptor (AhR) regulates silica-induced inflammation but not fibrosis by Beamer, Celine A, Seaver, Benjamin P, Shepherd, David M

“…The aryl hydrocarbon receptor (AhR), a ligand-activated transcription factor, is responsible for mediating a variety of pharmacological and toxicological…”
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IL-33 mediates multi-walled carbon nanotube (MWCNT)-induced airway hyper-reactivity via the mobilization of innate helper cells in the lung by Beamer, Celine A., Girtsman, Teri A., Seaver, Benjamin P., Finsaas, Krissy J., Migliaccio, Christopher T., Perry, Victoria K., Rottman, James B., Smith, Dirk E., Holian, Andrij

“…Abstract Allergic asthma is a chronic inflammatory disorder of the airway associated with bronchial obstruction, airway hyper-reactivity (AHR), and mucus…”
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Silica suppresses Toll-like receptor ligand-induced dendritic cell activation by Beamer, Celine A, Holian, Andrij

“…Inhalation of silica, without evidence of silicosis, is believed to predispose individuals to bacterial infections and impair respiratory immune functions…”
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Antigen-Presenting Cell Population Dynamics during Murine Silicosis by Beamer, Celine A, Holian, Andrij

“…Silicosis is an occupational lung disease resulting from the inhalation of silica particles over prolonged periods of time, which causes chronic inflammation…”
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Inhibition of TLR Ligand- and Interferon Gamma-Induced Murine Microglial Activation by Panax Notoginseng by Beamer, Celine A., Shepherd, David M.

“…Among the many products which influence microglial activation and resulting neuroinflammation, herbal medicine has recently drawn much attention due to its…”
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Acute Exposure to Crystalline Silica Reduces Macrophage Activation in Response to Bacterial Lipoproteins by Beamer, Gillian L, Seaver, Benjamin P, Jessop, Forrest, Shepherd, David M, Beamer, Celine A

“…Numerous studies have examined the relationship between alveolar macrophages (AMs) and crystalline silica (SiO2) using in vitro and in vivo immunotoxicity…”
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ROLE OF THE ARYL HYDROCARBON RECEPTOR (AHR) IN LUNG INFLAMMATION1 by Beamer, Celine A., Shepherd, David M.

“…Millions of individuals worldwide are afflicted with acute and chronic respiratory diseases, causing temporary and permanent disabilities and even death…”
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