Search Results - "Beamer, B"

The Physical and Biological Characterization of a Frail Mouse Model by Walston, Jeremy, Fedarko, Neal, Yang, Huanle, Leng, Sean, Beamer, Brock, Espinoza, Sara, Lipton, Anne, Zheng, Howie, Becker, Kevin

“…Background. The development of animal models that approximate human frailty is necessary to facilitate etiologic and treatment-focused frailty research. The…”
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Simple biologically informed inflammatory index of two serum cytokines predicts 10 year all-cause mortality in older adults by Varadhan, Ravi, Yao, Wenliang, Matteini, Amy, Beamer, Brock A, Xue, Qian-Li, Yang, Huanle, Manwani, Bhavish, Reiner, Alexander, Jenny, Nancy, Parekh, Neel, Fallin, M Daniele, Newman, Anne, Bandeen-Roche, Karen, Tracy, Russell, Ferrucci, Luigi, Walston, Jeremy

“…Individual measurements of inflammation have been utilized to assess adverse outcomes risk in older adults with varying degrees of success. This study was…”
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Glutathione Peroxidase Enzyme Activity in Aging by Espinoza, Sara E., Guo, Hongfei, Fedarko, Neal, DeZern, Amy, Fried, Linda P., Xue, Qian-Li, Leng, Sean, Beamer, Brock, Walston, Jeremy D.

“…Background. It is hypothesized that free radical damage contributes to aging. Age-related decline in activity of the antioxidant enzyme glutathione peroxidase…”
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Exploring biologically relevant pathways in frailty by Ho, Yen-Yi, Matteini, Amy M, Beamer, Brock, Fried, Linda, Xue, Qian-li, Arking, Dan E, Chakravarti, Aravinda, Fallin, M Daniele, Walston, Jeremy

“…Frailty is a late-life syndrome of vulnerability to adverse health outcomes characterized by a phenotype that includes muscle weakness, fatigue, and…”
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The Effect of Immobilization on the Native and Repaired Tendon-to-Bone Interface by Hettrich, C.M, Gasinu, S, Beamer, B.S, Fox, A, Ying, O, Deng, X.H, Rodeo, S.A

“…BACKGROUND:Little is known of the cellular events that occur in native or repaired tendons as a result of immobilization after injury. To examine this issue,…”
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A knowledge-rich approach to identifying semantic relations between nominals by Girju, R., Beamer, B., Rozovskaya, A., Fister, A., Bhat, S.

“…This paper describes a state-of-the-art supervised, knowledge-intensive approach to the automatic identification of semantic relations between nominals in…”
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Improving community ambulation after hip fracture: protocol for a randomised, controlled trial by Orwig, D, Mangione, KK, Baumgarten, M, Terrin, M, Fortinsky, R, Kenny, AM, Gruber-Baldini, AL, Beamer, B, Tosteson, ANA, Shardell, M, Magder, L, Binder, E, Koval, K, Resnick, B, Craik, RL, Magaziner, J

“…Abstract Introduction After a hip fracture in older persons, significant disability often remains; dependency in functional activities commonly persists beyond…”
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Pro115Gln and Pro12Ala PPAR gamma gene mutations in obesity and type 2 diabetes by Clement, K, Hercberg, S, Passinge, B, Galan, P, Varroud-Vial, M, Shuldiner, A.R, Beamer, B.A, Charpentier, G, Guy-Grand, B, Froguel, P

“…OBJECTIVE: Peroxisome-proliferator-activated receptors gamma (PPAR gamma), is a key regulator of adipocyte differentiation and energy balance. Two naturally…”
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Economic Value Of Improved Accuracy For Self-Monitoring Of Blood Glucose Devices For Type 1 Diabetes by McQueen, RB, Breton, M, Ott, M, Koa, H, Beamer, B, Campbell, J.D

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Interleukin-6 and interleukin-1 receptor antagonist in acute stroke by Beamer, N B, Coull, B M, Clark, W M, Hazel, J S, Silberger, J R

“…Elevated plasma levels of interleukin-6 (IL-6), a key regulator of the acute phase response that includes increased fibrinogen synthesis, have recently been…”
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Persistent inflammatory response in stroke survivors by BEAMER, N. B, COULL, B. M, CLARK, W. M, BRILEY, D. P, WYNN, M, SEXTON, G

“…Goals were to determine how long acute-phase markers remain elevated after ischemic stroke and how marker levels relate to stroke risk factors, stroke…”
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PPAR-γ Pro12Ala genotype and risk of cognitive decline in elders by Yaffe, K, Kanaya, A.M, Lindquist, K, Hsueh, W.C, Cummings, S.R, Beamer, B, Newman, A, Rosano, C, Li, R, Harris, T

“…Abstract Background The Pro12Ala polymorphism of peroxisome proliferator-activated receptor-gamma (PPAR-γ) has been associated with decreased risk of diabetes…”
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IL-6 gene variation is not associated with increased serum levels of IL-6, muscle, weakness, or frailty in older women by Walston, J., Arking, D.E., Fallin, D., Li, T., Beamer, B., Xue, Q., Ferrucci, L., Fried, L.P., Chakravarti, A.

“…Elevated levels of the inflammatory cytokine IL-6 are associated with the development of disability, frailty, and mortality in older adults. These outcomes are…”
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I palapala no ia aina – documenting the Hawaiian Kingdom: a colonial venture? by Kamanamaikalani Beamer, B., Kaeo Duarte, T.

“…Scholars have suggested that Western surveys and maps were tools used to aid colonizers in the dispossession of native people from their lands. While this was…”
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The Pro12Ala variant of peroxisome proliferator-activated receptor-γ2 (PPAR-γ2) is associated with measures of obesity in Mexican Americans by COLE, S. A, MITCHELL, B. D, HSUEH, W.-C, PINEDA, P, BEAMER, B. A, SHULDINER, A. R, COMUZZIE, A. G, BLANGERO, J, HIXSON, J. E

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Molecular scanning of the human peroxisome proliferator activated receptor gamma (hPPAR gamma) gene in diabetic Caucasians: identification of a Pro12Ala PPAR gamma 2 missense mutation by Yen, C J, Beamer, B A, Negri, C, Silver, K, Brown, K A, Yarnall, D P, Burns, D K, Roth, J, Shuldiner, A R

“…Peroxisome proliferator activated receptor-gamma (PPAR gamma) is a nuclear receptor that regulates adipocyte differentiation, and possibly lipid metabolism and…”
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Novel neuropeptide Y1 and Y5 receptor gene variants: associations with serum triglyceride and high-density lipoprotein cholesterol levels by Blumenthal, JB, Andersen, RE, Mitchell, BD, Seibert, MJ, Yang, H, Herzog, H, Beamer, BA, Franckowiak, SC, Walston, JD

“…Neuropeptide Y (NPY) appears to play a critical role in the integration of appetite and energy expenditure through NPY Y1 and Y5 receptor subtypes. Moreover,…”
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Analysis of the peroxisome proliferator activated receptor γ (PPARγ) gene in HAIRAN syndrome with obesity by Globerman, H., Zauberman, Y., Makarov, T., Beamer, B. A., Yen, C-J., Shuldiner, A. R., Harel, C., Karnieli, E.

“…Summary OBJECTIVES To test the hypothesis that the triad of hyperandrogenism, insulin resistance and acanthosis nigricans (HAIRAN syndrome) in the presence of…”
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Insulin response to glucose is lower in individuals homozygous for the Arg 64 variant of the β-3-adrenergic receptor by WALSTON, Jeremy, SILVER, Kristi, HILFIKER, Heather, ANDERSEN, Ross E, SEIBERT, Michael, BEAMER, Brock, ROTH, Jesse, POEHLMAN, Eric, SHULDINER, Alan R

“…Type 2 diabetes mellitus (type 2 DM) is a polygenic disorder with a variable phenotype that includes both insulin resistance and insulin secretory dysfunction…”
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Spontaneous echo contrast and hemorheologic abnormalities in cerebrovascular disease by Briley, D P, Giraud, G D, Beamer, N B, Spear, E M, Grauer, S E, Edwards, J M, Clark, W M, Sexton, G J, Coull, B M

“…Spontaneous echo contrast (SEC) is thought to represent a risk factor for cardioembolic stroke. In vitro studies suggest that SEC results from interaction…”
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