Search Results - "Beals, Joseph"
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Insulin resistance drives hepatic de novo lipogenesis in nonalcoholic fatty liver disease
Published in The Journal of clinical investigation (01-03-2020)“…BACKGROUNDAn increase in intrahepatic triglyceride (IHTG) is the hallmark feature of nonalcoholic fatty liver disease (NAFLD) and is decreased by weight loss…”
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2
Dynamic Shifts in the Composition of Resident and Recruited Macrophages Influence Tissue Remodeling in NASH
Published in Cell reports (Cambridge) (12-01-2021)“…Macrophage-mediated inflammation is critical in the pathogenesis of non-alcoholic steatohepatitis (NASH). Here, we describe that, with high-fat,…”
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3
The secret to a long ‘musclespan’ is a little hard work
Published in The Journal of physiology (01-05-2022)Get full text
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4
Progression of elite sport through technology is a fait accompli ; the line should be drawn from the start
Published in Journal of applied physiology (1985) (01-09-2024)Get full text
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5
Food-First Approach to Enhance the Regulation of Post-exercise Skeletal Muscle Protein Synthesis and Remodeling
Published in Sports medicine (Auckland) (01-02-2019)“…Protein recommendations are provided on a daily basis as defined by the recommended dietary allowance (RDA) at 0.80 g protein/kg/day. However, meal-based, as…”
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Consumption of whole eggs promotes greater stimulation of postexercise muscle protein synthesis than consumption of isonitrogenous amounts of egg whites in young men
Published in The American journal of clinical nutrition (01-12-2017)“…Protein in the diet is commonly ingested from whole foods that contain various macro- and micronutrients. However, the effect of consuming protein within its…”
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7
Decreased adipose tissue oxygenation associates with insulin resistance in individuals with obesity
Published in The Journal of clinical investigation (01-12-2020)“…BACKGROUNDData from studies conducted in rodent models have shown that decreased adipose tissue (AT) oxygenation is involved in the pathogenesis of…”
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When Exercising for Metabolic Health, the Work is Never Done, But HIIT Will Save You Time
Published in The journal of clinical endocrinology and metabolism (01-01-2021)Get full text
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Achieving Optimal Post-Exercise Muscle Protein Remodeling in Physically Active Adults through Whole Food Consumption
Published in Nutrients (16-02-2018)“…Dietary protein ingestion is critical to maintaining the quality and quantity of skeletal muscle mass throughout adult life. The performance of acute exercise…”
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10
Increased Adipose Tissue Fibrogenesis, Not Impaired Expandability, Is Associated With Nonalcoholic Fatty Liver Disease
Published in Hepatology (Baltimore, Md.) (01-09-2021)“…Background and Aims It is proposed that impaired expansion of subcutaneous adipose tissue (SAT) and an increase in adipose tissue (AT) fibrosis causes ectopic…”
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Anabolic sensitivity of postprandial muscle protein synthesis to the ingestion of a protein-dense food is reduced in overweight and obese young adults
Published in The American journal of clinical nutrition (01-10-2016)“…ABSTRACT Background: Excess body fat diminishes muscle protein synthesis rates in response to hyperinsulinemic-hyperaminoacidemic clamps. However, muscle…”
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12
Anabolic Resistance of Muscle Protein Turnover Comes in Various Shapes and Sizes
Published in Frontiers in nutrition (Lausanne) (05-05-2021)“…Anabolic resistance is defined by a blunted stimulation of muscle protein synthesis rates (MPS) to common anabolic stimuli in skeletal muscle tissue such as…”
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13
Small molecule SWELL1 complex induction improves glycemic control and nonalcoholic fatty liver disease in murine Type 2 diabetes
Published in Nature communications (10-02-2022)“…Type 2 diabetes is associated with insulin resistance, impaired pancreatic β-cell insulin secretion, and nonalcoholic fatty liver disease. Tissue-specific…”
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Postabsorptive and postprandial myofibrillar protein synthesis rates at rest and after resistance exercise in women with postmenopause
Published in Journal of applied physiology (1985) (01-06-2024)“…An adequate quality and quantity of skeletal muscle is relevant to support physical performance and metabolic health. Muscle protein synthesis (MPS) is an…”
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Obesity Alters the Muscle Protein Synthetic Response to Nutrition and Exercise
Published in Frontiers in nutrition (Lausanne) (13-06-2019)“…Improving the health of skeletal muscle is an important component of obesity treatment. Apart from allowing for physical activity, skeletal muscle tissue is…”
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Altered anabolic signalling and reduced stimulation of myofibrillar protein synthesis after feeding and resistance exercise in people with obesity
Published in The Journal of physiology (01-11-2018)“…Key points Lifestyle modifications that include the regular performance of exercise are probably important for counteracting the negative consequences of…”
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The Degree of Aminoacidemia after Dairy Protein Ingestion Does Not Modulate the Postexercise Anabolic Response in Young Men: A Randomized Controlled Trial
Published in The Journal of nutrition (01-09-2019)“…Resistance exercise and dietary protein stimulate muscle protein synthesis (MPS). The rate at which proteins are digested and absorbed into circulation alters…”
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Whole egg, but not egg white, ingestion induces mTOR colocalization with the lysosome after resistance exercise
Published in American Journal of Physiology: Cell Physiology (01-10-2018)“…We have recently demonstrated that whole egg ingestion induces a greater muscle protein synthetic (MPS) response when compared with isonitrogenous egg white…”
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Time-dependent regulation of postprandial muscle protein synthesis rates after milk protein ingestion in young men
Published in Journal of applied physiology (1985) (01-12-2019)“…The anabolic action of "fast" whey protein on the regulation of postprandial muscle protein synthesis has been established to be short-lived in healthy young…”
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Sepsis as 2 problems: Identifying sepsis at admission and predicting onset in the hospital using an electronic medical record–based acuity score
Published in Journal of critical care (01-04-2017)“…Early identification and treatment improve outcomes for patients with sepsis. Current screening tools are limited. We present a new approach, recognizing that…”
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