Search Results - "Beale, Rupert C L"

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    Cloth Masks May Prevent Transmission of COVID-19: An Evidence-Based, Risk-Based Approach by Clase, Catherine M, Fu, Edouard L, Joseph, Meera, Beale, Rupert C L, Dolovich, Myrna B, Jardine, Meg, Mann, Johannes F E, Pecoits-Filho, Roberto, Winkelmayer, Wolfgang C, Carrero, Juan J

    Published in Annals of internal medicine (15-09-2020)
    “…Clase et al discuss an evidence-based approach showing that cloth masks may prevent transmission of COVID-19. Physical distancing, hand hygiene, and…”
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    Somatic hypermutation at A.T pairs: polymerase error versus dUTP incorporation by Neuberger, Michael S, Di Noia, Javier M, Beale, Rupert C L, Williams, Gareth T, Yang, Zizhen, Rada, Cristina

    Published in Nature reviews. Immunology (01-02-2005)
    “…Somatic hypermutation of immunoglobulin genes occurs at both C.G pairs and A.T pairs. Mutations at C.G pairs are created by activation-induced deaminase…”
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    Mutational comparison of the single-domained APOBEC3C and double-domained APOBEC3F/G anti-retroviral cytidine deaminases provides insight into their DNA target site specificities by Langlois, Marc-André, Beale, Rupert C. L., Conticello, Silvestro G., Neuberger, Michael S.

    Published in Nucleic acids research (01-01-2005)
    “…Human APOBEC3F and APOBEC3G are double-domained deaminases that can catalyze dC→dU deamination in HIV-1 and MLV retroviral DNA replication intermediates,…”
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    Comparison of the Differential Context-dependence of DNA Deamination by APOBEC Enzymes: Correlation with Mutation Spectra in Vivo by Beale, Rupert C.L., Petersen-Mahrt, Svend K., Watt, Ian N., Harris, Reuben S., Rada, Cristina, Neuberger, Michael S.

    Published in Journal of molecular biology (26-03-2004)
    “…To investigate the extent to which in vivo mutation spectra might reflect the intrinsic specificities of active mutators, genetic and biochemical assays were…”
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    Opinion: Somatic hypermutation at A·T pairs: polymerase error versus dUTP incorporation by Neuberger, Michael S, Di Noia, Javier M, Beale, Rupert C L, Williams, Gareth T, Yang, Zizhen, Rada, Cristina

    Published in Nature reviews. Immunology (01-02-2005)
    “…Somatic hypermutation of immunoglobulin genes occurs at both C.G pairs and A.T pairs. Mutations at C.G pairs are created by activation-induced deaminase…”
    Get full text
    Journal Article