Search Results - "Beachy, Dawn E"

Characterization of a mechanism to inhibit ovarian follicle activation by Barilovits, Sarah J., Ph.D, Newsom, Kimberly J., Ph.D, Bickford, Justin S., Ph.D, Beachy, Dawn E., B.F.A, Rhoton-Vlasak, Alice, M.D, Nick, Harry S., Ph.D

“…Objective To demonstrate that a small molecule can induce the transcription factor Foxo3 in the ovary and lead to inhibition of follicle activation. Design…”
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Regulation of human microsomal prostaglandin E synthase-1 by IL-1β requires a distal enhancer element with a unique role for C/EBPβ by Walters, Jewell N, Bickford, Justin S, Newsom, Kimberly J, Beachy, Dawn E, Barilovits, Sarah J, Herlihy, John-David, Nick, Harry S

“…The studies of PGE2 (prostaglandin E2) biosynthesis have focused primarily on the role of cyclo-oxygenases. Efforts have shifted towards the specific PGE2…”
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A distal enhancer controls cytokine-dependent human cPLA2α gene expression[S] by Bickford, Justin S., Beachy, Dawn E., Newsom, Kimberly J., Barilovits, Sarah J., Herlihy, John-David H., Qiu, Xiaolei, Walters, Jewell N., Li, Ning, Nick, Harry S.

“…Specific control of group IVA cytosolic phospholipase A2 (cPLA2α or PLA2G4A) expression modulates arachidonic acid production, thus tightly regulating the…”
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Altered cellular localisation and expression, together with unconventional protein trafficking, of prion protein, PrPC, in type 1 diabetes by Hiller, Helmut, Yang, Changjun, Beachy, Dawn E., Kusmartseva, Irina, Candelario-Jalil, Eduardo, Posgai, Amanda L., Nick, Harry S., Schatz, Desmond, Atkinson, Mark A., Wasserfall, Clive H.

“…Aims/hypothesis Normal cellular prion protein (PrP C ) is a conserved mammalian glycoprotein found on the outer plasma membrane leaflet through a…”
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Monogenic Diabetes and Integrated Stress Response Genes Display Altered Gene Expression in Type 1 Diabetes by Hiller, Helmut, Beachy, Dawn E, Lebowitz, Joseph J, Engler, Stefanie, Mason, Justin R, Miller, Douglas R, Kusmarteva, Irina, Jacobsen, Laura M, Posgai, Amanda L, Khoshbouei, Habibeh, Oram, Richard A, Schatz, Desmond A, Hattersley, Andrew T, Bodenmiller, Bernd, Atkinson, Mark A, Nick, Harry S, Wasserfall, Clive H

“…Type 1 diabetes (T1D) has a multifactorial autoimmune etiology, involving environmental prompts and polygenic predisposition. We hypothesized that pancreata…”
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Endothelin-1-mediated vasoconstriction alters cerebral gene expression in iron homeostasis and eicosanoid metabolism by Bickford, Justin S, Ali, Narjis F, Nick, Jerelyn A, Al-Yahia, Musab, Beachy, Dawn E, Doré, Sylvain, Nick, Harry S, Waters, Michael F

“…Abstract Endothelins are potent vasoconstrictors and signaling molecules. Their effects are broad, impacting processes ranging from neurovascular and…”
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A TEAD1/p65 complex regulates the eutherian-conserved MnSOD intronic enhancer, eRNA transcription and the innate immune response by Chokas, Ann L., Bickford, Justin S., Barilovits, Sarah J., Rogers, Richard J., Qiu, Xiaolei, Newsom, Kimberly J., Beachy, Dawn E., Nick, Harry S.

“…Manganese superoxide dismutase (MnSOD), a critical anti-oxidant enzyme, detoxifies the mitochondrial-derived reactive oxygen species, superoxide, elicited…”
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cPLA(2)α gene activation by IL-1β is dependent on an upstream kinase pathway, enzymatic activation and downstream 15-lipoxygenase activity: a positive feedback loop by Walters, Jewell N, Bickford, Justin S, Beachy, Dawn E, Newsom, Kimberly J, Herlihy, John-David H, Peck, Molly V, Qiu, Xiaolei, Nick, Harry S

“…Cytosolic phospholipase A(2)α (cPLA(2)α) is the most widely studied member of the Group IV PLA(2) family. The enzyme is Ca(2+)-dependent with specificity for…”
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Effect of allergy and inflammation on eicosanoid gene expression in CFTR deficiency by Bickford, Justin S, Mueller, Christian, Newsom, Kimberly J, Barilovits, Sarah J, Beachy, Dawn E, Herlihy, John D, Keeler, Benjamin, Flotte, Terence R, Nick, Harry S

“…Abstract Background Allergic bronchopulmonary aspergillosis (ABPA) is a complicating factor in cystic fibrosis (CF), affecting 2–15% of patients. We…”
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FOXO3 Expression in the Human Ovary [6OP] by Swenson, Helen Paige, Beachy, Dawn E., Barilovits, Sarah J., Nick, Harry S., Rush, Demaretta S., Rhoton-Vlasak, Alice

“…INTRODUCTION: To assess FOXO3 gene expression levels and members of the KL-PI3K-AKT-FOXO3 pathway in pre- and postmenopausal human ovaries. To evaluate in a…”
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Altered cellular localisation and expression, together with unconventional protein trafficking, of prion protein, PrP C , in type 1 diabetes by Hiller, Helmut, Yang, Changjun, Beachy, Dawn E, Kusmartseva, Irina, Candelario-Jalil, Eduardo, Posgai, Amanda L, Nick, Harry S, Schatz, Desmond, Atkinson, Mark A, Wasserfall, Clive H

“…Normal cellular prion protein (PrP ) is a conserved mammalian glycoprotein found on the outer plasma membrane leaflet through a glycophosphatidylinositol…”
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Distinct Functions of CCAAT Enhancer-binding Protein Isoforms in the Regulation of Manganese Superoxide Dismutase during Interleukin-1β Stimulation by Qiu, Xiaolei, Aiken, Kimberly J., Chokas, Ann L., Beachy, Dawn E., Nick, Harry S.

“…The mitochondrial antioxidant enzyme manganese superoxide dismutase (Mn-SOD) is crucial in maintaining cellular and organismal homeostasis. Mn-SOD expression…”
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cPLA2α gene activation by IL-1β is dependent on an upstream kinase pathway, enzymatic activation and downstream 15-lipoxygenase activity: A positive feedback loop by Walters, Jewell N., Bickford, Justin S., Beachy, Dawn E., Newsom, Kimberly J., Herlihy, John-David H., Peck, Molly V., Qiu, Xiaolei, Nick, Harry S.

“…Cytosolic phospholipase A2α (cPLA2α) is the most widely studied member of the Group IV PLA2 family. The enzyme is Ca2+-dependent with specificity for…”
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cPLA sub(2[alpha] gene activation by IL-1[beta] is dependent on an upstream kinase pathway, enzymatic activation and downstream 15-lipoxygenase activity: A positive feedback loop) by Walters, Jewell N, Bickford, Justin S, Beachy, Dawn E, Newsom, Kimberly J, Herlihy, John-David H, Peck, Molly V, Qiu, Xiaolei, Nick, Harry S

“…Cytosolic phospholipase A sub(2[alpha] (cPLA) sub(2)[alpha]) is the most widely studied member of the Group IV PLA sub(2 family. The enzyme is Ca)…”
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Distinct functions of CCAAT enhancer-binding protein isoforms in the regulation of manganese superoxide dismutase during interleukin-1beta stimulation by Qiu, Xiaolei, Aiken, Kimberly J, Chokas, Ann L, Beachy, Dawn E, Nick, Harry S

“…The mitochondrial antioxidant enzyme manganese superoxide dismutase (Mn-SOD) is crucial in maintaining cellular and organismal homeostasis. Mn-SOD expression…”
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Distinct Functions of CCAAT Enhancer-binding Protein Isoforms in the Regulation of Manganese Superoxide Dismutase during Interleukin-1β Stimulation by Xiaolei Qiu, Kimberly J. Aiken, Ann L. Chokas, Dawn E. Beachy, Harry S. Nick

“…The mitochondrial antioxidant enzyme manganese superoxide dismutase (Mn-SOD) is crucial in maintaining cellular and organismal homeostasis. Mn-SOD expression…”
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