Search Results - "Beach, Adam"

Lithocholic bile acid selectively kills neuroblastoma cells, while sparing normal neuronal cells by Goldberg, Alexander A, Beach, Adam, Davies, Gerald F, Harkness, Troy A A, Leblanc, Andréa, Titorenko, Vladimir I

“…Aging is one of the major risk factors of cancer. The onset of cancer can be postponed by pharmacological and dietary anti-aging interventions. We recently…”
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A Reappraisal of the Quakers and the Development of Antislavery Thought by Beach, Adam R.

“…A review of Brycchan Carey, From Peace to Freedom: Quaker Rhetoric and the Birth of American Antislavery, 1657–1761, which reexamines the development of Quaker…”
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In search of housekeeping pathways that regulate longevity by Beach, Adam, Titorenko, Vladimir I.

“…Comment on: Goldberg AA, et al. Aging 2010; 2:393-414…”
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Bile acids induce apoptosis selectively in androgen-dependent and -independent prostate cancer cells by Goldberg, Alexander A, Titorenko, Vladimir I, Beach, Adam, Sanderson, J Thomas

“…Prostate cancer is a prevalent age-related disease in North America, accounting for about 15% of all diagnosed cancers. We have previously identified…”
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Mechanisms by which different functional states of mitochondria define yeast longevity by Beach, Adam, Leonov, Anna, Arlia-Ciommo, Anthony, Svistkova, Veronika, Lutchman, Vicky, Titorenko, Vladimir I

“…Mitochondrial functionality is vital to organismal physiology. A body of evidence supports the notion that an age-related progressive decline in mitochondrial…”
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Macromitophagy, neutral lipids synthesis, and peroxisomal fatty acid oxidation protect yeast from "liponecrosis", a previously unknown form of programmed cell death by Sheibani, Sara, Richard, Vincent, Beach, Adam, Leonov, Anna, Feldman, Rachel, Mattie, Sevan, Khelghatybana, Leila, Piano, Amanda, Greenwood, Michael, Vali, Hojatollah, Titorenko, Vladimir I.

“…We identified a form of cell death called "liponecrosis." It can be elicited by an exposure of the yeast Saccharomyces cerevisiae to exogenous palmitoleic acid…”
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Lithocholic bile acid accumulated in yeast mitochondria orchestrates a development of an anti-aging cellular pattern by causing age-related changes in cellular proteome by Beach, Adam, Richard, Vincent R, Bourque, Simon, Boukh-Viner, Tatiana, Kyryakov, Pavlo, Gomez-Perez, Alejandra, Arlia-Ciommo, Anthony, Feldman, Rachel, Leonov, Anna, Piano, Amanda, Svistkova, Veronika, Titorenko, Vladimir I

“…We have previously revealed that exogenously added lithocholic bile acid (LCA) extends the chronological lifespan of the yeast Saccharomyces cerevisiae,…”
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Caloric restriction delays yeast chronological aging by remodeling carbohydrate and lipid metabolism, altering peroxisomal and mitochondrial functionalities, and postponing the onsets of apoptotic and liponecrotic modes of regulated cell death by Arlia-Ciommo, Anthony, Leonov, Anna, Beach, Adam, Richard, Vincent R, Bourque, Simon D, Burstein, Michelle T, Kyryakov, Pavlo, Gomez-Perez, Alejandra, Koupaki, Olivia, Feldman, Rachel, Titorenko, Vladimir I

“…A dietary regimen of caloric restriction delays aging in evolutionarily distant eukaryotes, including the budding yeast . Here, we assessed how caloric…”
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Mechanisms through which lithocholic acid delays yeast chronological aging under caloric restriction conditions by Arlia-Ciommo, Anthony, Leonov, Anna, Mohammad, Karamat, Beach, Adam, Richard, Vincent R, Bourque, Simon D, Burstein, Michelle T, Goldberg, Alexander A, Kyryakov, Pavlo, Gomez-Perez, Alejandra, Koupaki, Olivia, Titorenko, Vladimir I

“…All presently known geroprotective chemical compounds of plant and microbial origin are caloric restriction mimetics because they can mimic the beneficial…”
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Mechanism of liponecrosis, a distinct mode of programmed cell death by Richard, Vincent R, Beach, Adam, Piano, Amanda, Leonov, Anna, Feldman, Rachel, Burstein, Michelle T, Kyryakov, Pavlo, Gomez-Perez, Alejandra, Arlia-Ciommo, Anthony, Baptista, Stefanie, Campbell, Cory, Goncharov, Daniel, Pannu, Sonia, Patrinos, Dimitri, Sadri, Behnaz, Svistkova, Veronika, Victor, Andrew, Titorenko, Vladimir I

“…An exposure of the yeast Saccharomyces cerevisiae to exogenous palmitoleic acid (POA) elicits "liponecrosis," a mode of programmed cell death (PCD) which…”
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Lithocholic acid extends longevity of chronologically aging yeast only if added at certain critical periods of their lifespan by Burstein, Michelle T., Kyryakov, Pavlo, Beach, Adam, Richard, Vincent R., Koupaki, Olivia, Gomez-Perez, Alejandra, Leonov, Anna, Levy, Sean, Noohi, Forough, Titorenko, Vladimir I.

“…Our studies revealed that LCA (lithocholic bile acid) extends yeast chronological lifespan if added to growth medium at the time of cell inoculation. We also…”
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Global Slavery, Old World Bondage, and Aphra Behn's "Abdelazer" by Beach, Adam R.

“…Criticism on Abdelazer has suffered from the critical assumption that New World plantation slavery was the norm for the early-modern world, and that slaves…”
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African Slaves, English Slave Narratives, and Early Modern Morocco by Beach, Adam R.

“…Scholars who work on English slave narratives written by those who were held in bondage in Morocco need to contextualize these narratives in relation to the…”
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Restoration Poetry and the Failure of English Tangier by Beach, Adam R.

“…My essay investigates three poems that respond to the Moroccan siege of English Tangier in 1680 and its aftermath: an anonymous satire, "Rochester's Farewell";…”
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Impact of Three State Practices on Effectiveness of Hot-Mix Asphalt Overlay by Dawson, Tyler A., Baladi, Gilbert Y., Beach, Adam C., Dean, Christopher M., Haider, Syed Waqar, Chatti, Karim

“…The effectiveness of pavement treatments is a function of several factors, including material quality, design, distribution of pavement condition states…”
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Interspecies Chemical Signals Released into the Environment may Create Xenohormetic, Hormetic and Cytostatic Selective Forces that Drive the Ecosystemic Evolution of Longevity Regulation Mechanisms by Burstein, Michelle T., Beach, Adam, Richard, Vincent R., Koupaki, Olivia, Gomez-Perez, Alejandra, Goldberg, Alexander A., Kyryakov, Pavlo, Bourque, Simon D., Glebov, Anastasia, Titorenko, Vladimir I.

“…Various organisms (i.e., bacteria, fungi, plants and animals) within an ecosystem can synthesize and release into the environment certain longevity-extending…”
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The Letters of Samuel Pepys 1656-1703 by Beach, Adam R.

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Anti-Colonist Discourse, Tragicomedy, and the "American" Behn by Beach, Adam R.

“…Beach discusses Aphra Behn's play "The Widdow Ranter." Writing to a hostile audience who scorned English colonials, Behn takes advantage of the mixed…”
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The Creation of a Classical Language in the Eighteenth Century: Standardizing English, Cultural Imperialism, and the Future of the Literary Canon by Beach, Adam R.

“…The drive to standardize the English language in the eighteen century had a variety of political and social goals. The effort did succeed in making English the…”
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A PROFOUND PESSIMISM ABOUT THE EMPIRE: "THE ISLE OF PINES", ENGLISH DEGENERACY AND DUTCH SUPREMACY by Beach, Adam R.

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