Search Results - "Be, Céline"

Optimization of a Fragment-Based Screening Hit toward Potent DOT1L Inhibitors Interacting in an Induced Binding Pocket by Scheufler, Clemens, Möbitz, Henrik, Gaul, Christoph, Ragot, Christian, Be, Céline, Fernández, César, Beyer, Kim S, Tiedt, Ralph, Stauffer, Frédéric

“…Mixed lineage leukemia (MLL) gene rearrangement induces leukemic transformation by ectopic recruitment of disruptor of telomeric silencing 1-like protein…”
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Structural basis of indisulam-mediated RBM39 recruitment to DCAF15 E3 ligase complex by Bussiere, Dirksen E., Xie, Lili, Srinivas, Honnappa, Shu, Wei, Burke, Ashley, Be, Celine, Zhao, Junping, Godbole, Adarsh, King, Dan, Karki, Rajeshri G., Hornak, Viktor, Xu, Fangmin, Cobb, Jennifer, Carte, Nathalie, Frank, Andreas O., Frommlet, Alexandra, Graff, Patrick, Knapp, Mark, Fazal, Aleem, Okram, Barun, Jiang, Songchun, Michellys, Pierre-Yves, Beckwith, Rohan, Voshol, Hans, Wiesmann, Christian, Solomon, Jonathan M., Paulk, Joshiawa

“…The anticancer agent indisulam inhibits cell proliferation by causing degradation of RBM39, an essential mRNA splicing factor. Indisulam promotes an…”
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Author Correction: Structural basis of indisulam-mediated RBM39 recruitment to DCAF15 E3 ligase complex by Bussiere, Dirksen E., Xie, Lili, Srinivas, Honnappa, Shu, Wei, Burke, Ashley, Be, Celine, Zhao, Junping, Godbole, Adarsh, King, Dan, Karki, Rajeshri G., Hornak, Viktor, Xu, Fangmin, Cobb, Jennifer, Carte, Nathalie, Frank, Andreas O., Frommlet, Alexandra, Graff, Patrick, Knapp, Mark, Fazal, Aleem, Okram, Barun, Jiang, Songchun, Michellys, Pierre-Yves, Beckwith, Rohan, Voshol, Hans, Wiesmann, Christian, Solomon, Jonathan M., Paulk, Joshiawa

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Applications of Biophysics in High-Throughput Screening Hit Validation by Genick, Christine Clougherty, Barlier, Danielle, Monna, Dominique, Brunner, Reto, Bé, Céline, Scheufler, Clemens, Ottl, Johannes

“…For approximately a decade, biophysical methods have been used to validate positive hits selected from high-throughput screening (HTS) campaigns with the goal…”
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Identification of a Novel Allosteric Inhibitory Site on Tryptophan Hydroxylase 1 Enabling Unprecedented Selectivity Over all Related Hydroxylases by Petrassi, Mike, Barber, Rob, Be, Celine, Beach, Sarah, Cox, Brian, D'Souza, Anne-Marie, Duggan, Nick, Hussey, Martin, Fox, Roy, Hunt, Peter, Jarai, Gabor, Kosaka, Takatoshi, Oakley, Paul, Patel, Viral, Press, Neil, Rowlands, David, Scheufler, Clemens, Schmidt, Oliver, Srinivas, Honnappa, Turner, Mary, Turner, Rob, Westwick, John, Wolfreys, Alison, Pathan, Nuzhat, Watson, Simon, Thomas, Matthew

“…Pulmonary arterial hypertension (PAH) has demonstrated multi-serotonin receptor dependent pathologies, characterized by increased tone (5-HT receptor) and…”
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884-P: Duodenal Electroporation and Semaglutide Effectively Eliminate Need for Insulin in Type 2 Diabetes Patients by Busch, Celine BE, Meiring, Suzanne, Van Baar, Annieke CG, Holleman, Frits, Nieuwdorp, Max, Bergman, Jacques

“…Introduction: Re-Cellularization via Electroporation Therapy (ReCET™) is an endoscopic ablation technique which uses electroporation of cellular membranes to…”
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Structural States of RORγt: X‐ray Elucidation of Molecular Mechanisms and Binding Interactions for Natural and Synthetic Compounds by Kallen, Joerg, Izaac, Aude, Be, Celine, Arista, Luca, Orain, David, Kaupmann, Klemens, Guntermann, Christine, Hoegenauer, Klemens, Hintermann, Samuel

“…The T‐cell‐specific retinoic acid receptor (RAR)‐related orphan receptor‐γ (RORγt) is a key transcription factor for the production of pro‐inflammatory Th17…”
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852-P: Duodenal Recellularization via Electroporation Therapy (ReCET) and GLP-1 RA to Replace Insulin in T2D Patients—EMINENT Study Six-Month Results by BUSCH, CELINE B.E., MEIRING, SUZANNE, VAN BAAR, ANNIEKE C.G., HOLLEMAN, FRITS, NIEUWDORP, MAX, BERGMAN, JACQUES J.

“…Introduction: Re-Cellularization via Electroporation Therapy (ReCET™), a novel endoscopic procedure using electroporation to elicit apoptosis of the duodenal…”
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Discovery and Characterization of Clinical Candidate LXE408 as a Kinetoplastid-Selective Proteasome Inhibitor for the Treatment of Leishmaniases by Nagle, Advait, Biggart, Agnes, Be, Celine, Srinivas, Honnappa, Hein, Andreas, Caridha, Diana, Sciotti, Richard J, Pybus, Brandon, Kreishman-Deitrick, Mara, Bursulaya, Badry, Lai, Yin H, Gao, Mu-Yun, Liang, Fang, Mathison, Casey J. N, Liu, Xiaodong, Yeh, Vince, Smith, Jeffrey, Lerario, Isabelle, Xie, Yongping, Chianelli, Donatella, Gibney, Michael, Berman, Ashley, Chen, Yen-Liang, Jiricek, Jan, Davis, Lauren C, Liu, Xianzhong, Ballard, Jaime, Khare, Shilpi, Eggimann, Fabian Kurt, Luneau, Alexandre, Groessl, Todd, Shapiro, Michael, Richmond, Wendy, Johnson, Kevin, Rudewicz, Patrick J, Rao, Srinivasa P. S, Thompson, Christopher, Tuntland, Tove, Spraggon, Glen, Glynne, Richard J, Supek, Frantisek, Wiesmann, Christian, Molteni, Valentina

“…Visceral leishmaniasis is responsible for up to 30,000 deaths every year. Current treatments have shortcomings that include toxicity and variable efficacy…”
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Human Memory B Cells Harbor Diverse Cross-Neutralizing Antibodies against BK and JC Polyomaviruses by Lindner, John M., Cornacchione, Vanessa, Sathe, Atul, Be, Celine, Srinivas, Honnappa, Riquet, Elodie, Leber, Xavier-Charles, Hein, Andreas, Wrobel, Matthias B., Scharenberg, Meike, Pietzonka, Thomas, Wiesmann, Christian, Abend, Johanna, Traggiai, Elisabetta

“…Human polyomaviruses cause a common childhood infection worldwide and typically elicit a neutralizing antibody and cellular immune response, while establishing…”
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Role of the Intestine and Its Gut Microbiota in Metabolic Syndrome and Obesity by Busch, Celine B E, Bergman, Jacques J G H M, Nieuwdorp, Max, van Baar, Annieke C G

“…The metabolic syndrome (MetSyn) is currently one of the biggest global health challenges because of its impact on public health. MetSyn includes the cluster of…”
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Quantitative and functional characterisation of extracellular vesicles after passive loading with hydrophobic or cholesterol-tagged small molecules by Tréton, Gwenola, Sayer, Claudia, Schürz, Melanie, Jaritsch, Maria, Müller, Anna, Matea, Cristian-Tudor, Stanojlovic, Vesna, Melo-Benirschke, Heloisa, Be, Celine, Krembel, Caroline, Rodde, Stephane, Haffke, Matthias, Hintermann, Samuel, Marzinzik, Andreas, Ripoche, Sébastien, Blöchl, Constantin, Hollerweger, Julia, Auer, Daniela, Cabrele, Chiara, Huber, Christian G., Hintersteiner, Martin, Wagner, Trixie, Lingel, Andreas, Meisner-Kober, Nicole

“…Extracellular vesicles (EVs) are nanosized intercellular messengers that bear enormous application potential as biological drug delivery vehicles. Much…”
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Discovery of Novel Quinoline-Based Proteasome Inhibitors for Human African Trypanosomiasis (HAT) by Koester, Dennis C., Marx, Vanessa M., Williams, Sarah, Jiricek, Jan, Dauphinais, Maxime, René, Olivier, Miller, Sarah L., Zhang, Lei, Patra, Debjani, Chen, Yen-Liang, Cheung, Harry, Gable, Jonathan, Lakshminarayana, Suresh B., Osborne, Colin, Galarneau, Jean-Rene, Kulkarni, Upendra, Richmond, Wendy, Bretz, Angela, Xiao, Linda, Supek, Frantisek, Wiesmann, Christian, Honnappa, Srinivas, Be, Celine, Mäser, Pascal, Kaiser, Marcel, Ritchie, Ryan, Barrett, Michael P., Diagana, Thierry T., Sarko, Christopher, Rao, Srinivasa P. S.

“…Human African Trypanosomiasis (HAT) is a vector-borne disease caused by kinetoplastid parasites of the Trypanosoma genus. The disease proceeds in two stages,…”
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A small-molecule inhibitor of C5 complement protein by Jendza, Keith, Kato, Mitsunori, Salcius, Michael, Srinivas, Honnappa, De Erkenez, Andrea, Nguyen, Anh, McLaughlin, Doug, Be, Celine, Wiesmann, Christian, Murphy, Jason, Bolduc, Philippe, Mogi, Muneto, Duca, Jose, Namil, Abdel, Capparelli, Michael, Darsigny, Veronique, Meredith, Erik, Tichkule, Ritesh, Ferrara, Luciana, Heyder, Jessica, Liu, Fang, Horton, Patricia A., Romanowski, Michael J., Schirle, Markus, Mainolfi, Nello, Anderson, Karen, Michaud, Gregory A.

“…The complement pathway is an important part of the immune system, and uncontrolled activation is implicated in many diseases. The human complement component 5…”
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Structural States of ROR[gamma]t: X-ray Elucidation of Molecular Mechanisms and Binding Interactions for Natural and Synthetic Compounds by Kallen, Joerg, Izaac, Aude, Be, Celine, Arista, Luca, Orain, David, Kaupmann, Klemens, Guntermann, Christine, Hoegenauer, Klemens, Hintermann, Samuel

“…The T-cell-specific retinoic acid receptor (RAR)-related orphan receptor-[gamma] (ROR[gamma]t) is a key transcription factor for the production of…”
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Pickering乳液的发展趋势——颗粒形态及其应用 by Danae Gonzalez Ortiz, Celine Pochat-Bohatier, Julien Cambedouzou, Mikhael Bechelany, Philippe Miele

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Nano-Precision Tweezers for Mechanosensitive Proteins and Beyond by Yang, Taehyun, Park, Celine, Rah, Sang-Hyun, Shon, Min Ju

“…Mechanical forces play pivotal roles in regulating cell shape, function, and fate. Key players that govern the mechanobiological interplay are the…”
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Non-Protein-Coding RNAs and their Interacting RNA-Binding Proteins in the Plant Cell Nucleus by Celine Charon Ana Beatriz Moreno Florian Bardou Martin Crespi

“…The complex responses of eukaryotic cells to external factors are governed by several transcriptional and post-transcriptional processes. Several of them occur…”
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Hydroxychloroquine, Interleukin-6 Receptor Antagonists and Corticoid Treatments of Acute COVID-19 Infection: Psychiatric Symptoms and Mental Disorders 4 Months Later by Matthieu Gasnier, Walid Choucha, David Montani, Nicolas Noël, Céline Verstuyft, Francois Radiguer

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Demographic, Lifestyle, and Physical Health Predictors of Sickness Absenteeism in Nursing: A Meta-Analysis by Gohar, Basem, Lariviere, Michel, Lightfoot, Nancy, Lariviere, Celine, Wenghofer, Elizabeth, Nowrouzi-kia, Behdin

“…Background: Sickness absenteeism is an area of concern in nursing and is more concerning given the recent impacts of the COVID-19 pandemic on healthcare. This…”
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