Search Results - "Bazán‐Perkins, Blanca"

Regulation of Myosin Light-Chain Phosphatase Activity to Generate Airway Smooth Muscle Hypercontractility by Álvarez-Santos, Mayra D., Álvarez-González, Marisol, Estrada-Soto, Samuel, Bazán-Perkins, Blanca

“…Smooth muscle is a central structure involved in the regulation of airway tone. In addition, it plays an important role in the development of some pathologies…”
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Serum integrin accumulation during asthma exacerbation: The role of matrix metalloproteinases by Olivia, Tellez‐Jimenez, Christian, Trejo‐Jasso, Patricia, Ramos‐Ramirez, Rocío, Chapela, Luis, Miguel‐Reyes José, Carmen, López‐Estrada Erika, Blanca, Bazán‐Perkins

“…The inflammation caused by asthma exacerbation can lead to permanent changes in the airways and loss of lung function. Integrins are membrane receptors that…”
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Asthma and COVID-19: a controversial relationship by Dounce-Cuevas, Carlos A, Flores-Flores, Angélica, Bazán, Mariana S, Portales-Rivera, Victor, Morelos-Ulíbarri, Araceli A, Bazán-Perkins, Blanca

“…Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection induces a spectrum of clinical manifestations that depend on the immune response of the…”
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Functional mechanism of tracheal relaxation, antiasthmatic, and toxicological studies of 6‐hydroxyflavone by Flores‐Flores, Angélica, Estrada‐Soto, Samuel, Millán‐Pacheco, César, Bazán‐Perkins, Blanca, Villalobos‐Molina, Rafael, Moreno‐Fierros, Leticia, Hernández‐Pando, Rogelio, García‐Jiménez, Sara, Rivera‐Leyva, Julio César

“…Previously, we described tracheal rat rings relaxation by several flavonoids, being 6‐hydroxyflavone (6‐HOF) the most active derivative of the series. Thus,…”
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Role of airway smooth muscle cell phenotypes in airway tone and obstruction in guinea pig asthma model by Álvarez-Santos, Mayra D, Álvarez-González, Marisol, Eslava-De-Jesus, Elizabeth, González-López, Angel, Pacheco-Alba, Ivonne, Pérez-Del-Valle, Yazmín, Rojas-Madrid, Rodrigo, Bazán-Perkins, Blanca

“…Airway obstruction (AO) in asthma is driven by airway smooth muscle (ASM) contraction. AO can be induced extrinsically by direct stimulation of ASM with…”
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Ex Vivo and In Silico Approaches of Tracheal Relaxation through Calcium Channel Blockade of 6-Aminoflavone and Its Toxicological Studies in Murine Models by Flores-Flores, Angélica, Estrada-Soto, Samuel, Millán-Pacheco, César, Bazán-Perkins, Blanca, Hernández-Pando, Rogelio, Ibarra-Barajas, Maximiliano, Villalobos-Molina, Rafael

“…Asthma is a condition in which a person's airways become inflamed, narrowed, and produce greater amounts of mucus than normal. It can cause shortness of…”
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Sexual Dimorphism in the Regulation of Estrogen, Progesterone, and Androgen Receptors by Sex Steroids in the Rat Airway Smooth Muscle Cells by Abraham Zarazúa, Aliesha González-Arenas, Gabriela Ramírez-Vélez, Blanca Bazán-Perkins, Christian Guerra-Araiza, María G. Campos-Lara

“…The role of sex hormones in lung is known. The three main sex steroid receptors, estrogen, progesterone, and androgen, have not been sufficiently studied in…”
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cGMP reduces the sarcoplasmic reticulum Ca2+ loading in airway smooth muscle cells: a putative mechanism in the regulation of Ca2+ by cGMP by Bazán-Perkins, Blanca

“…Ca 2+ and cGMP have opposite roles in many physiological processes likely due to a complex negative feedback regulation between them. Examples of opposite…”
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Relaxant effect of structurally related flavonoids on isolated tracheal rat rings: a SAR study by Flores-Flores, Angélica, Hidalgo-Figueroa, Sergio, Villalobos-Molina, Rafael, Ibarra-Barajas, Maximiliano, Bazán-Perkins, Blanca, Navarrete-Vázquez, Gabriel, Estrada-Soto, Samuel

“…In the search for potential new antiasthmatic drugs, the ex vivo relaxing effect and structural activity relationship (SAR) studies of a series of ten…”
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Spontaneous changes in guinea-pig respiratory pattern during barometric plethysmography: role of catecholamines and nitric oxide by Bazán-Perkins, Blanca, Vargas, Mario H, Sánchez-Guerrero, Edgar, Chávez, Jaime, Montaño, Luis M

“…Barometric plethysmography for unrestrained animals is a non-invasive method that allows repetitive measurements of pulmonary function, but habituation of the…”
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Antigen-induced airway hyperresponsiveness in absence of broncho-obstruction in sensitized guinea pigs by Ramos-Ramírez, Patricia, Campos, María G., Martínez-Cordero, Erasmo, Bazán-Perkins, Blanca, García-Zepeda, Eduardo

“…ABSTRACTBackground: Airway obstruction after antigen challenge is not always observed in patients with allergic asthma, even if they develop…”
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Airway responsiveness measured by barometric plethysmography in guinea pigs by Vargas, Mario H, Sommer, Bettina, Bazán-Perkins, Blanca, Montaño, Luis M

“…Barometric plethysmography has become an increasingly used method to indirectly measure respiratory function in unrestrained freely-moving animals. This…”
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LTD4 induces hyperresponsiveness to histamine in bovine airway smooth muscle: role of SR-ATPase Ca2+ pump and tyrosine kinase by Carbajal, Verónica, Vargas, Mario H, Flores-Soto, Edgar, Martínez-Cordero, Erasmo, Bazán-Perkins, Blanca, Montaño, Luis M

“…Airway hyperresponsiveness is a key feature of asthma, but its mechanisms remain poorly understood. Leukotriene D(4) (LTD(4)) is one of the few molecules…”
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Capacitative Ca2+ Entry During Ca2+ Undershoot in Bovine Airway Smooth Muscle by Bazán-Perkins, Blanca, Sánchez-Guerrero, Edgar, Campos, María G.

“…In numerous cells, Ca 2+ undershoot is commonly observed after withdrawing stimulus that release Ca 2+ from intracellular stores. In airway smooth muscle…”
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Resting calcium influx in airway smooth muscle by Montaño, Luis M, Bazán-Perkins, Blanca

“…Plasma membrane Ca2+ leak remains the most uncertain of the cellular Ca2+ regulation pathways. During passive Ca2+ influx in non-stimulated smooth muscle…”
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Aerosolized Polymerized Type I Collagen Reduces Airway Inflammation and Remodelling in a Guinea Pig Model of Allergic Asthma by Moreno-Alvarez, Paola, Sánchez-Guerrero, Edgar, Martínez-Cordero, Erasmo, Hernández-Pando, Rogelio, Campos, María G, Cetina, Lucely, Bazán-Perkins, Blanca

“…Collagen-polyvinylpyrrolidone (Collagen-PVP) has been demonstrated to elicit immunomodulatory properties in different chronic inflammatory diseases…”
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The impact of education level and socioeconomic status on the association between depressive symptoms and memory in an older population in Latin America: An exploratory analysis from the Brazilian Longitudinal Study of Aging (ELSI-BRAZIL) by Loss, Karla, Fandino, Wilson, Almarie, Bassel, Bazan-Perkins, Blanca, Minetto, Julia, Aranis, Nadine, Monaco, Thiago, Aladab, Aisha, Pacheco-Barrios, Kevin, Fregni, Felipe

“…The globally increasing older population raises concerns about age-related conditions, including cognitive impairment and depressive symptoms. In Latin…”
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Airway Hyperresponsiveness in Asthma Model Occurs Independently of Secretion of β1 Integrins in Airway Wall and Focal Adhesions Proteins Down Regulation by Álvarez-Santos, Mayra, Carbajal, Verónica, Tellez-Jiménez, Olivia, Martínez-Cordero, Erasmo, Ruiz, Victor, Hernández-Pando, Rogelio, Lascurain, Ricardo, Santibañez-Salgado, Alfredo, Bazan-Perkins, Blanca

“…ABSTRACT The extracellular domains of some membrane proteins can be shed from the cell. A similar phenomenon occurs with β1 integrins (α1β1 and α2β1) in guinea…”
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cGMP reduces the sarcoplasmic reticulum Ca^sup 2+^ loading in airway smooth muscle cells: a putative mechanism in the regulation of Ca^sup 2+^ by cGMP by Bazán-perkins, Blanca

“…Ca^sup 2+^ and cGMP have opposite roles in many physiological processes likely due to a complex negative feedback regulation between them. Examples of opposite…”
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Antigen‐induced airway hyperresponsiveness and obstruction is related to caveolin‐1 expression in airway smooth muscle in a guinea pig asthma model by Álvarez‐Santos, Mayra, Ramos‐Ramírez, Patricia, Gutiérrez‐Aguilar, Fernando, Sánchez‐Hernández, Sandra, Lascurain, Ricardo, Olmos‐Zuñiga, Raúl, Jasso‐Victoria, Rogelio, Bobadilla, Norma A, Bazan‐Perkins, Blanca

“…Background Caveolin‐1 is a fundamental signalling scaffold protein involved in contraction; however, the role of caveolin‐1 in airway responsiveness remains…”
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