Atrial myxoma as a mimicker of intracardiac thrombus in Behçet's syndrome: a case study with histopathological confirmation

Cardiomyopathies cause most intracardiac thrombosis (ICT), and Behçet's syndrome (BS) is a rare inflammatory disease that can be responsible for a proportion of ICT. Other inflammatory disorders involved in the aetiology of ICT include antiphospholipid syndrome, Henoch-Schonlein purpura, COVID-...

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Bibliographic Details
Published in:	Clinical and experimental rheumatology Vol. 42; no. 10; p. 2092
Main Authors:	Ak, Tumay, Bayrakdar, Bahar, Batur, Sebnem, Durmaz, Emine Sebnem, Cimci, Murat, Seyahi, Emire
Format:	Journal Article
Language:	English
Published:	Italy 01-10-2024
Subjects:	Behcet Syndrome - complications Behcet Syndrome - diagnosis Diagnosis, Differential Female Heart Atria - diagnostic imaging Heart Atria - pathology Heart Diseases - diagnostic imaging Heart Diseases - etiology Heart Neoplasms - complications Heart Neoplasms - diagnostic imaging Heart Neoplasms - pathology Humans Immunosuppressive Agents - therapeutic use Magnetic Resonance Imaging Middle Aged Myxoma - complications Myxoma - diagnostic imaging Myxoma - pathology Thrombosis - diagnostic imaging Thrombosis - etiology Treatment Outcome
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Summary:	Cardiomyopathies cause most intracardiac thrombosis (ICT), and Behçet's syndrome (BS) is a rare inflammatory disease that can be responsible for a proportion of ICT. Other inflammatory disorders involved in the aetiology of ICT include antiphospholipid syndrome, Henoch-Schonlein purpura, COVID-19, and Loeffler endocarditis. ICT usually occur during the active phase of BS, and they have a close relationship with vascular involvement. Atrial myxomas are benign cardiac tumours arising from the interatrial septum. They can lead to a substantial acute phase response, making them difficult to distinguish from inflammatory diseases. In this case study, we present a 46-year-old female BS patient who presented with constitutional symptoms mimicking BS flare in a routine follow-up visit and was diagnosed with left atrial myxoma after administration of several lines of immunosuppressives. Then, she underwent surgical tumour excision, and a histopathological examination confirmed the diagnosis.In conclusion, atrial myxoma should be kept in mind first of all when suspecting ICT, and advanced imaging methods such as cardiac magnetic resonance imaging (MRI) should be used if necessary.
ISSN:	0392-856X
DOI:	10.55563/clinexprheumatol/j29rnr