Cyanoacrylate and hyaluronic acid combination on palatal donor site management after de‐epithelialized graft harvesting

Cyanoacrylate and hyaluronic acid combination on palatal donor site management after de‐epithelialized graft harvesting

Background Although soft tissue substitutes showed promising improvement in the past decade, epithelialized gingival graft (EGG) is still widely used in periodontal plastic surgery applications. Donor site management after EGG harvesting has been challenging for clinicians. This study aimed to compa...

Full description

Saved in:
Bibliographic Details
Published in:Journal of periodontology (1970) Vol. 94; no. 4; pp. 519 - 528
Main Authors: Parlak, Hanife Merva, Durmaz, Murat Haktan, Bayrak, Havanur, Yilmaz, Birtan Tolga, Keceli, H. Gencay
Format: Journal Article
Language:English
Published: United States 01-04-2023
Subjects:
absorbable gelatin sponge
Cyanoacrylates
donor site
Gelatin
Humans
Hyaluronic Acid
Pain, Postoperative
Retrospective Studies
tissue grafts
wound healing
tissue grafts
wound healing
cyanoacrylates
donor site
absorbable gelatin sponge
hyaluronic acid
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Background Although soft tissue substitutes showed promising improvement in the past decade, epithelialized gingival graft (EGG) is still widely used in periodontal plastic surgery applications. Donor site management after EGG harvesting has been challenging for clinicians. This study aimed to compare the effectiveness of cyanoacrylate, hyaluronic acid, and their combination in palatal donor site management after EGG harvesting. Methods Data from 89 patients were included and categorized as gelatin sponge (GS), gelatin sponge with either cyanoacrylate (GS + CY), hyaluronic acid (GS + HA), or both (GS + CY + HA). The data of pain perception (PP), quantity of analgesics (QA), secondary bleeding (SB), epithelization level (EL), and color match (CM) were assessed retrospectively. Results The GS + CY and GS + HA + CY groups showed lower PP scores compared to the GS and GS + HA groups (p < 0.05). The QA was higher in the GS group compared to the GS + CY and GS + HA + CY groups (p < 0.001). All study groups showed greater EL than GS group on day 7 (p < 0.001). On day 14, full EL was present in 81% of the patients in the GS + HA + CY group, which was higher than the other groups (p < 0.001). All study groups reported lower SB in the first 3 days, which was lower compared to the GS group (p < 0.001) and showed higher CM scores than the GS group on days 7 and 14 (p < 0.001). Conclusions CY application reduces pain and analgesic intake and HA may support the wound healing with increased EL. Using the CY‐HA combination provides additional benefits for donor site management.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0022-3492
1943-3670
DOI:10.1002/JPER.22-0409