Search Results - "Bayoumi, Noha A."
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Penetration enhancer-containing spanlastics (PECSs) for transdermal delivery of haloperidol: in vitro characterization, ex vivo permeation and in vivo biodistribution studies
Published in Drug delivery (2018)“…Haloperidol (Hal) is one of the widely used antipsychotic drugs. When orally administered, it suffers from low bioavailability due to hepatic first pass…”
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Gold nanorod–loaded (PLGA-PEG) nanocapsules as near-infrared controlled release model of anticancer therapeutics
Published in Lasers in medical science (01-10-2020)“…Despite of high in vitro anticancer efficacy of many chemotherapeutics, their in vivo use is limited due to lack of biocompatibility and tumor targeting…”
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Biocompatible mucoadhesive nanoparticles for brain targeting of ropinirole hydrochloride: Formulations, radiolabeling and biodistribution
Published in Biopolymers (01-06-2022)“…Two nanoformulations with mucoadhesive properties and brain‐targeting mechanisms were designed to deliver the anti‐Parkinson's drug, ropinirole hydrochloride…”
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99mTc radiolabeling of polyethylenimine capped carbon dots for tumor targeting: synthesis, characterization and biodistribution
Published in International journal of radiation biology (03-07-2021)“…Due to the favorable physicochemical properties and the biocompatibility, carbon dots (CDs) have gained a great attention as a tumor targeting agent. This…”
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99m Tc radiolabeling of polyethylenimine capped carbon dots for tumor targeting: synthesis, characterization and biodistribution
Published in International journal of radiation biology (03-07-2021)“…Due to the favorable physicochemical properties and the biocompatibility, carbon dots (CDs) have gained a great attention as a tumor targeting agent. This…”
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Pyrazole derivatives as potent EGFR inhibitors: synthesis, biological evaluation and in silico and biodistribution study
Published in Future medicinal chemistry (01-12-2022)“…Synthesis of pyrazole derivatives as EGFR inhibitors. Cytotoxicity and EGFR inhibitory effect were evaluated by…”
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A novel gold-polymer-antibody conjugate for targeted (radio-photothermal) treatment of HepG2 cells
Published in Journal of biomaterials science. Polymer ed. (2023)“…Localization of the near-infrared (NIR) plasmonic nanoparticles at the tumor sites is essential for safe and efficient photothermal therapy of cancer. In this…”
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Targeted photoimmunotherapy based on photosensitizer-antibody conjugates for multiple myeloma treatment
Published in Journal of photochemistry and photobiology. B, Biology (01-01-2020)“…Despite the high in vitro efficacy of photodynamic therapeutics, lack of tumor targeting significantly reduces their in vivo efficacy and thus limits their…”
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Laser-responsive liposome for selective tumor targeting of nitazoxanide nanoparticles
Published in European journal of pharmaceutical sciences (01-01-2018)“…Nitazoxanide [2-(Acetyloxy)-N-(5-nitro-2-thiazolyl)benzamide], usually referred as NTZ, is an antiparasites drug with a potential anti-cancer reactivity…”
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Brain targeted rivastigmine mucoadhesive thermosensitive In situ gel: Optimization, in vitro evaluation, radiolabeling, in vivo pharmacokinetics and biodistribution
Published in Journal of drug delivery science and technology (01-02-2018)“…The purpose of our investigation was to promote the bioavailability and the brain delivery of rivastigmine tartarate (RV) through optimization of mucoadhesive…”
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