Search Results - "Bayo, Juan"

Switching from subcutaneous to oral semaglutide in type 2 diabetes: A prospective study by Martínez‐Montoro, José Ignacio, Picón‐César, María José, Generoso‐Piñar, Marta, Fernández‐Valero, Andrea, López‐Montalbán, Ángel, Simón‐Frapolli, Víctor José, Hernández‐Bayo, Juan, Pinzón‐Martín, José Luis, Tinahones, Francisco J.

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Characterization of screenings from urban wastewater treatment plants: Alternative approaches to landfill disposal by De la Torre-Bayo, Juan Jesús, Martín-Pascual, Jaime, Torres-Rojo, Juan C., Zamorano, Montserrat

“…Increasingly, wastewater treatment plants are laying the foundation for a circular economy. A novel approach to operating these plants is to redefine them as…”
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A comprehensive study of epigenetic alterations in hepatocellular carcinoma identifies potential therapeutic targets by Bayo, Juan, Fiore, Esteban J., Dominguez, Luciana M., Real, Alejandrina, Malvicini, Mariana, Rizzo, Manglio, Atorrasagasti, Catalina, García, Mariana G., Argemi, Josepmaria, Martinez, Elisabeth D., Mazzolini, Guillermo D.

“…[Display omitted] •Mutations and expression alterations of epigenetic modifiers are frequent in HCC.•Jumonji lysine demethylase inhibitors normalize aggressive…”
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Jumonji Inhibitors Overcome Radioresistance in Cancer through Changes in H3K4 Methylation at Double-Strand Breaks by Bayo, Juan, Tran, Tram Anh, Wang, Lei, Peña-Llopis, Samuel, Das, Amit K., Martinez, Elisabeth D.

“…We have uncovered a role for Jumonji inhibitors in overcoming radioresistance through KDM5B inhibition. Pharmacological blockade of Jumonji demethylases with…”
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4-methylumbelliferone-mediated polarization of M1 macrophages correlate with decreased hepatocellular carcinoma aggressiveness in mice by Rodríguez, Marcelo M., Onorato, Agostina, Cantero, María José, Domínguez, Luciana, Bayo, Juan, Fiore, Esteban, García, Mariana, Atorrasagasti, Catalina, Canbay, Ali, Malvicini, Mariana, Mazzolini, Guillermo D.

“…Hepatocellular carcinoma (HCC) arises in the setting of advanced liver fibrosis, a dynamic and complex inflammatory disease. The tumor microenvironment (TME)…”
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Taking advantage of the potential of mesenchymal stromal cells in liver regeneration: Cells and extracellular vesicles as therapeutic strategies by Fiore, Esteban Juan, Domínguez, Luciana María, Bayo, Juan, García, Mariana Gabriela, Mazzolini, Guillermo Daniel

“…Cell-based therapies for acute and chronic liver diseases are under continuous progress. Mesenchymal stem/stromal cells (MSCs) are multipotent cells able to…”
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Human umbilical cord perivascular cells-derived extracellular vesicles mediate the transfer of IGF-I to the liver and ameliorate hepatic fibrogenesis in mice by Fiore, Esteban, Domínguez, Luciana M., Bayo, Juan, Malvicini, Mariana, Atorrasagasti, Catalina, Rodriguez, Marcelo, Cantero, María José, García, Mariana, Yannarelli, Gustavo, Mazzolini, Guillermo

“…Extracellular vesicles (EVs) can mediate mesenchymal stromal cells (MSCs) paracrine effects. We aimed to evaluate the therapeutic potential of human umbilical…”
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Mesenchymal stromal cells engineered to produce IGF-I by recombinant adenovirus ameliorate liver fibrosis in mice by Fiore, Esteban J, Bayo, Juan M, Garcia, Mariana G, Malvicini, Mariana, Lloyd, Rodrigo, Piccioni, Flavia, Rizzo, Manglio, Peixoto, Estanislao, Sola, M Beatriz, Atorrasagasti, Catalina, Alaniz, Laura, Camilletti, María A, Enguita, Mónica, Prieto, Jesús, Aquino, Jorge B, Mazzolini, Guillermo

“…Liver cirrhosis involves chronic wound healing and fibrotic processes. Mesenchymal stromal cells (MSCs) are multipotent adult progenitor cells that are used as…”
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Targeting hyaluronan metabolism-related molecules associated with resistant tumor-initiating cells potentiates chemotherapy efficacy in lung cancer by Díaz, Marco Aurelio, Fusco, Mariel, Benítez, Constanza Arriola, Gayet, Fernando, García, Ludmila, Victoria, Lucia, Jaramillo, Sebastián, Bayo, Juan, Zubieta, Mariana Rodríguez, Rizzo, Manglio M., Piccioni, Flavia, Malvicini, Mariana

“…The success of chemotherapy regimens in patients with non-small cell lung cancer (NSCLC) could be restricted at least in part by cancer stem cells (CSC) niches…”
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Analyzing the production, quality, and potential uses of solid recovered fuel from screening waste of municipal wastewater treatment plants by De la Torre-Bayo, Juan Jesús, Zamorano, Montserrat, Torres-Rojo, Juan C., Rodríguez, Miguel L., Martín-Pascual, Jaime

“…Over time, wastewater management evolves into a circular model, producing energy and moving towards zero waste. The usual screening waste treatment is the…”
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Identification of a novel actin-dependent signal transducing module allows for the targeted degradation of GLI1 by Schneider, Philipp, Miguel Bayo-Fina, Juan, Singh, Rajeev, Kumar Dhanyamraju, Pavan, Holz, Philipp, Baier, Aninja, Fendrich, Volker, Ramaswamy, Annette, Baumeister, Stefan, Martinez, Elisabeth D., Lauth, Matthias

“…The Down syndrome-associated DYRK1A kinase has been reported as a stimulator of the developmentally important Hedgehog (Hh) pathway, but cells from Down…”
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Osteosarcoma cells exhibit functional interactions with stromal cells, fostering a lung microenvironment conducive to the establishment of metastatic tumor cells by Valenzuela Alvarez, Matías J. P., Gutierrez, Luciana M., Bayo, Juan M., Cantero, María J., Garcia, Mariana G., Bolontrade, Marcela F.

“…Background Osteosarcoma (OS) stands out as the most common bone tumor, with approximately 20% of the patients receiving a diagnosis of metastatic OS at their…”
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Chromatographic Scalable Method to Isolate Engineered Extracellular Vesicles Derived from Mesenchymal Stem Cells for the Treatment of Liver Fibrosis in Mice by Domínguez, Luciana M, Bueloni, Bárbara, Cantero, Ma José, Albornoz, Milagros, Pacienza, Natalia, Biani, Celeste, Luzzani, Carlos, Miriuka, Santiago, García, Mariana, Atorrasagasti, Catalina, Yannarelli, Gustavo, Bayo, Juan, Fiore, Esteban, Mazzolini, Guillermo

“…New therapeutic options for liver cirrhosis are needed. Mesenchymal stem cell (MSC)-derived extracellular vesicles (EVs) have emerged as a promising tool for…”
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Modified mesenchymal stromal cells by in vitro transcribed mRNA: a therapeutic strategy for hepatocellular carcinoma by Cantero, María José, Bueloni, Barbara, Gonzalez Llamazares, Lucrecia, Fiore, Esteban, Lameroli, Lucia, Atorrasagasti, Catalina, Mazzolini, Guillermo, Malvicini, Mariana, Bayo, Juan, García, Mariana G

“…Mesenchymal stromal cells (MSCs) tropism for tumours allows their use as carriers of antitumoural factors and in vitro transcribed mRNA (IVT mRNA) is a…”
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4-methylumbelliferone inhibits hepatocellular carcinoma growth by decreasing IL-6 production and angiogenesis by Piccioni, Flavia, Fiore, Esteban, Bayo, Juan, Atorrasagasti, Catalina, Peixoto, Estanislao, Rizzo, Manglio, Malvicini, Mariana, Tirado-González, Irene, García, Mariana G, Alaniz, Laura, Mazzolini, Guillermo

“…Cirrhosis is characterized by an excessive accumulation of extracellular matrix components including hyaluronic acid (HA) and is widely considered a…”
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Hepatic SPARC Expression Is Associated with Inflammasome Activation during the Progression of Non-Alcoholic Fatty Liver Disease in Both Mice and Morbidly Obese Patients by Onorato, Agostina M, Lameroli Mauriz, Lucía, Bayo, Juan, Fiore, Esteban, Cantero, María José, Bueloni, Barbara, García, Mariana, Lagües, Cecilia, Martínez-Duartez, Pedro, Menaldi, Gabriel, Paleari, Nicolas, Atorrasagasti, Catalina, Mazzolini, Guillermo D

“…The severity of non-alcoholic fatty liver disease (NAFLD) ranges from simple steatosis to steatohepatitis, and it is not yet clearly understood which patients…”
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Single-agent metronomic versus weekly oral vinorelbine as first-line chemotherapy in patients with HR-positive/HER2-negative advanced breast cancer: The randomized Tempo Breast study by Freyer, Gilles, Martinez-Jañez, Noelia, Kukielka-Budny, Bożena, Ulanska, Malgorzata, Bourgeois, Hugues, Muñoz, Montserrat, Morales, Serafin, Calero, Juan Bayo, Cortesi, Laura, Pintér, Tamás, Palácová, Markéta, Cherciu, Nelli, Petru, Edgar, Ettl, Johannes, de Almeida, Cécilia, Villanova, Gustavo, Raymond, Romain, Minh, Christine Ta Thanh, Rodrigues, Ana, Cazzaniga, Marina E.

“…Single-agent oral vinorelbine is a standard of care for hormone receptor (HR)-positive/human epidermal growth factor receptor 2 (HER2)-negative advanced breast…”
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Relationship between Medication-Related Osteonecrosis of the Jaw and CDK4/6 Inhibitors in Breast Cancer by Senín, Loreto Domínguez, Pancorbo, David Morales, Garcés, María Yeray Rodríguez, Santos-Rubio, María Dolores, Calero, Juan Bayo

“…We aimed to evaluate the use of CDK4/6 inhibitors as a risk factor for medication-related osteonecrosis of the jaw (MRONJ) in a cohort of patients with…”
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Increased migration of human mesenchymal stromal cells by autocrine motility factor (AMF) resulted in enhanced recruitment towards hepatocellular carcinoma by Bayo, Juan, Fiore, Esteban, Aquino, Jorge B, Malvicini, Mariana, Rizzo, Manglio, Peixoto, Estanislao, Andriani, Oscar, Alaniz, Laura, Piccioni, Flavia, Bolontrade, Marcela, Podhajcer, Osvaldo, Garcia, Mariana G, Mazzolini, Guillermo

“…Several reports described the migration of human mesenchymal stromal cells (MSCs) towards tumor-released factors. Autocrine motility factor (AMF) is produced…”
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A unique maternal and placental galectin signature upon SARS-CoV-2 infection suggests galectin-1 as a key alarmin at the maternal-fetal interface by Zhao, Fangqi, Tallarek, Ann-Christin, Wang, Yiru, Xie, Yiran, Diemert, Anke, Lu-Culligan, Alice, Vijayakumar, Pavithra, Kittmann, Enrico, Urbschat, Christopher, Bayo, Juan, Arck, Petra C, Farhadian, Shelli F, Dveksler, Gabriela S, Garcia, Mariana G, Blois, Sandra M

“…The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic imposed a risk of infection and disease in pregnant women and neonates. Successful…”
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