Search Results - "Bayley, S T"

Mapping of cellular protein-binding sites on the products of early-region 1A of human adenovirus type 5 by EGAN, C, JELSMA, T. N, HOWE, J. A, BAYLEY, S. T, FERGUSON, B, BRANTON, P. E

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Functional interactions within adenovirus E1A protein complexes by Barbeau, D, Charbonneau, R, Whalen, S G, Bayley, S T, Branton, P E

“…The transforming potential of adenovirus E1A oncogene products derives largely from the formation of complexes with cellular proteins, including the p105Rb…”
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Induction of apoptosis by adenovirus type 5 E1A in rat cells requires a proliferation block by Mymryk, J S, Shire, K, Bayley, S T

“…Infection with Ad5dl520EIB-, an adenovirus producing only the 243 residue E1A protein and lacking the E1B region, caused apoptosis in normal rat kidney (NRK)…”
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Retinoblastoma Growth Suppressor and a 300-kDa Protein Appear to Regulate Cellular DNA Synthesis by Howe, John A., Mymryk, Joe S., Egan, Cay, Branton, Philip E., Bayley, Stanley T.

“…Previous work has suggested that oncogenic transformation by the E1A gene products of adenovirus type 5 may be mediated through interactions with at least two…”
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Effects of Ad5 E1A mutant viruses on the cell cycle in relation to the binding of cellular proteins including the retinoblastoma protein and cyclin A by Howe, J A, Bayley, S T

“…We have examined the ability of Ad5 E1A 12S viruses with deletions in E1A exon 1 to induce quiescent baby rat kidney cells to progress through the cell cycle…”
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Binding of the Rb1 protein to E1A products is required for adenovirus transformation by Egan, C, Bayley, S T, Branton, P E

“…Several cellular proteins, including polypeptides of 300, 107 and 105kDa, associate with the products of the E1A gene of adenovirus type 5. Here we show that…”
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Induction of gene expression by exon 2 of the major E1A proteins of adenovirus type 5 by MYMRYK, J. S, BAYLEY, S. T

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Induction of the cell cycle in baby rat kidney cells by adenovirus type 5 E1A in the absence of E1B and a possible influence of p53 by SHEPHERD, S. E, HOWE, J. A, MYMRYK, J. S, BAYLEY, S. T

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Sequences in E1A proteins of human adenovirus 5 required for cell transformation, repression of a transcriptional enhancer, and induction of proliferating cell nuclear antigen by Jelsma, T N, Howe, J A, Mymryk, J S, Evelegh, C M, Cunniff, N F, Bayley, S T

“…A range of deletion and other mutants in the coding region of the E1A gene of Ad5 has been assayed for transformation of baby rat kidney (BRK) cells in…”
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Induction of AP-1 DNA-binding activity and c-fos mRNA by the adenovirus 243R E1A protein and cyclic AMP requires domains necessary for transformation by GEDRICH, R. W, BAYLEY, S. T, ENGEL, D. A

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Multiple pathways for gene activation in rodent cells by the smaller adenovirus 5 E1A protein and their relevance to growth and transformation by Mymryk, Joe S, Bayley, Stanley T

“…1 Department of Biochemistry and 2 Department of Biology, McMaster University, Hamilton, Ontario, Canada L8S 4K1 By immunoprecipitating protein products from…”
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Role of phosphorylation near the amino terminus of adenovirus type 5 early region 1A proteins by Dumont, Daniel J, Marcellus, Richard C, Bayley, Stanley T, Branton, Philip E

“…1 Molecular Virology and Immunology Programme, Department of Pathology and 2 Department of Biology, McMaster University, Hamilton, Ontario, Canada L8N 3Z5 and…”
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Use of deletion and point mutants spanning the coding region of the adenovirus 5 E1A gene to define a domain that is essential for transcriptional activation by Jelsma, T N, Howe, J A, Evelegh, C M, Cunniff, N F, Skiadopoulos, M H, Floroff, M R, Denman, J E, Bayley, S T

“…To help in identifying functional domains within Ad5 E1A proteins, we have constructed a series of mutants that create deletions throughout these products. We…”
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Multiple pathways for activation of E2A expression in human KB cells by the 243R E1A protein of adenovirus type 5 by Mymryk, J S, Bayley, S T

“…Adenovirus type 5 (Ad5) mutant dl520, which produces only the smaller 243 residue (243R) E1A protein, induced efficient production of the viral E2A 72-kDa DNA…”
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Transformation by human adenoviruses by Branton, P E, Bayley, S T, Graham, F L

“…When, approximately 10 years ago, it was shown that the functions essential for cell transformation were localized in a small region of the adenovirus genome,…”
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Peptide maps and N-terminal sequences of polypeptides from early region 1A of human adenovirus 5 by DOWNEY, J. F, EVELEGH, C. M, BRANTON, P. E, BAYLEY, S. T

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Mapping of a 14,000-dalton antigen to early region 4 of the human adenovirus 5 genome by Downey, J F, Rowe, D T, Bacchetti, S, Graham, F L, Bayley, S T

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Quantitative analysis of regions of adenovirus E1A products involved in interactions with cellular proteins by Barbeau, D, Marcellus, R C, Bacchetti, S, Bayley, S T, Branton, P E

“…Human adenovirus E1A proteins and oncogene products of several other DNA tumour viruses derive much of their oncogenic potential from interactions with…”
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Protein kinase activity immunoprecipitated from adenovirus infected cells by sera from tumor-bearing hamsters by Branton, P E, Lassam, N J, Downey, J F, Yee, S P, Graham, F L, Mak, S, Bayley, S T

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Disruption of the coordinate expression of muscle genes in a transfected BC3H1 myoblast cell line producing a low level of the adenovirus E1A transforming protein by Mymryk, J S, Oakes, J D, Muthuswamy, S K, D'Amico, P, Bayley, S T, Lee, R W

“…Mouse BC3H1 myoblasts were stably transfected with the adenovirus 5 E1A gene. One clonal line, BC3E7, was found to differ in some important respects from those…”
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