Search Results - "Bayer, Florian P"

Defining the carrier proteome limit for single-cell proteomics by Cheung, Tommy K., Lee, Chien-Yun, Bayer, Florian P., McCoy, Atticus, Kuster, Bernhard, Rose, Christopher M.

“…Single-cell proteomics by mass spectrometry (SCoPE-MS) is a recently introduced method to quantify multiplexed single-cell proteomes. While this technique has…”
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Robust, reproducible and quantitative analysis of thousands of proteomes by micro-flow LC–MS/MS by Bian, Yangyang, Zheng, Runsheng, Bayer, Florian P., Wong, Cassandra, Chang, Yun-Chien, Meng, Chen, Zolg, Daniel P., Reinecke, Maria, Zecha, Jana, Wiechmann, Svenja, Heinzlmeir, Stephanie, Scherr, Johannes, Hemmer, Bernhard, Baynham, Mike, Gingras, Anne-Claude, Boychenko, Oleksandr, Kuster, Bernhard

“…Nano-flow liquid chromatography tandem mass spectrometry (nano-flow LC–MS/MS) is the mainstay in proteome research because of its excellent sensitivity but…”
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Data, Reagents, Assays and Merits of Proteomics for SARS-CoV-2 Research and Testing by Zecha, Jana, Lee, Chien-Yun, Bayer, Florian P., Meng, Chen, Grass, Vincent, Zerweck, Johannes, Schnatbaum, Karsten, Michler, Thomas, Pichlmair, Andreas, Ludwig, Christina, Kuster, Bernhard

“…As the COVID-19 pandemic continues to spread, research on SARS-CoV-2 is also rapidly evolving and the number of associated manuscripts on preprint servers is…”
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CurveCurator: a recalibrated F-statistic to assess, classify, and explore significance of dose–response curves by Bayer, Florian P., Gander, Manuel, Kuster, Bernhard, The, Matthew

“…Dose-response curves are key metrics in pharmacology and biology to assess phenotypic or molecular actions of bioactive compounds in a quantitative fashion…”
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SIMSI-Transfer: Software-Assisted Reduction of Missing Values in Phosphoproteomic and Proteomic Isobaric Labeling Data Using Tandem Mass Spectrum Clustering by Hamood, Firas, Bayer, Florian P., Wilhelm, Mathias, Kuster, Bernhard, The, Matthew

“…Isobaric stable isotope labeling techniques such as tandem mass tags (TMTs) have become popular in proteomics because they enable the relative quantification…”
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Decrypting lysine deacetylase inhibitor action and protein modifications by dose-resolved proteomics by Chang, Yun-Chien, Gnann, Christian, Steimbach, Raphael R., Bayer, Florian P., Lechner, Severin, Sakhteman, Amirhossein, Abele, Miriam, Zecha, Jana, Trendel, Jakob, The, Matthew, Lundberg, Emma, Miller, Aubry K., Kuster, Bernhard

“…Lysine deacetylase inhibitors (KDACis) are approved drugs for cutaneous T cell lymphoma (CTCL), peripheral T cell lymphoma (PTCL), and multiple myeloma, but…”
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A new mass analyzer shakes up the proteomics field by Kuster, Bernhard, Tüshaus, Johanna, Bayer, Florian P

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Robust Microflow LC-MS/MS for Proteome Analysis: 38 000 Runs and Counting by Bian, Yangyang, Bayer, Florian P, Chang, Yun-Chien, Meng, Chen, Hoefer, Stefanie, Deng, Nan, Zheng, Runsheng, Boychenko, Oleksandr, Kuster, Bernhard

“…Microflow liquid chromatography tandem mass spectrometry (μLC–MS/MS) is becoming a viable alternative to nanoflow LC–MS/MS for the analysis of proteomes. We…”
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Unified Workflow for the Rapid and In-Depth Characterization of Bacterial Proteomes by Abele, Miriam, Doll, Etienne, Bayer, Florian P., Meng, Chen, Lomp, Nina, Neuhaus, Klaus, Scherer, Siegfried, Kuster, Bernhard, Ludwig, Christina

“…Bacteria are the most abundant and diverse organisms among the kingdoms of life. Due to this excessive variance, finding a unified, comprehensive, and safe…”
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Evaluation of Disposable Trap Column nanoLC–FAIMS–MS/MS for the Proteomic Analysis of FFPE Tissue by Eckert, Stephan, Chang, Yun-Chien, Bayer, Florian P, The, Matthew, Kuhn, Peer-Hendrik, Weichert, Wilko, Kuster, Bernhard

“…Proteomic biomarker discovery using formalin-fixed paraffin-embedded (FFPE) tissue requires robust workflows to support the analysis of large cohorts of…”
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Decrypting drug actions and protein modifications by dose- and time-resolved proteomics by Zecha, Jana, Bayer, Florian P, Wiechmann, Svenja, Woortman, Julia, Berner, Nicola, Müller, Julian, Schneider, Annika, Kramer, Karl, Abril-Gil, Mar, Hopf, Thomas, Reichart, Leonie, Chen, Lin, Hansen, Fynn M, Lechner, Severin, Samaras, Patroklos, Eckert, Stephan, Lautenbacher, Ludwig, Reinecke, Maria, Hamood, Firas, Prokofeva, Polina, Vornholz, Larsen, Falcomatà, Chiara, Dorsch, Madeleine, Schröder, Ayla, Venhuizen, Anton, Wilhelm, Stephanie, Médard, Guillaume, Stoehr, Gabriele, Ruland, Jürgen, Grüner, Barbara M, Saur, Dieter, Buchner, Maike, Ruprecht, Benjamin, Hahne, Hannes, The, Matthew, Wilhelm, Mathias, Kuster, Bernhard

“…Although most cancer drugs modulate the activities of cellular pathways by changing posttranslational modifications (PTMs), little is known regarding the…”
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Illuminating phenotypic drug responses of sarcoma cells to kinase inhibitors by phosphoproteomics by Lee, Chien-Yun, The, Matthew, Meng, Chen, Bayer, Florian P, Putzker, Kerstin, Müller, Julian, Streubel, Johanna, Woortman, Julia, Sakhteman, Amirhossein, Resch, Moritz, Schneider, Annika, Wilhelm, Stephanie, Kuster, Bernhard

“…Kinase inhibitors (KIs) are important cancer drugs but often feature polypharmacology that is molecularly not understood. This disconnect is particularly…”
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Mass spectrometry-based draft of the mouse proteome by Giansanti, Piero, Samaras, Patroklos, Bian, Yangyang, Meng, Chen, Coluccio, Andrea, Frejno, Martin, Jakubowsky, Hannah, Dobiasch, Sophie, Hazarika, Rashmi R., Rechenberger, Julia, Calzada-Wack, Julia, Krumm, Johannes, Mueller, Sebastian, Lee, Chien-Yun, Wimberger, Nicole, Lautenbacher, Ludwig, Hassan, Zonera, Chang, Yun-Chien, Falcomatà, Chiara, Bayer, Florian P., Bärthel, Stefanie, Schmidt, Tobias, Rad, Roland, Combs, Stephanie E., The, Matthew, Johannes, Frank, Saur, Dieter, de Angelis, Martin Hrabe, Wilhelm, Mathias, Schneider, Günter, Kuster, Bernhard

“…The laboratory mouse ranks among the most important experimental systems for biomedical research and molecular reference maps of such models are essential…”
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Prosit-TMT: Deep Learning Boosts Identification of TMT-Labeled Peptides by Gabriel, Wassim, The, Matthew, Zolg, Daniel P., Bayer, Florian P., Shouman, Omar, Lautenbacher, Ludwig, Schnatbaum, Karsten, Zerweck, Johannes, Knaute, Tobias, Delanghe, Bernard, Huhmer, Andreas, Wenschuh, Holger, Reimer, Ulf, Médard, Guillaume, Kuster, Bernhard, Wilhelm, Mathias

“…The prediction of fragment ion intensities and retention time of peptides has gained significant attention over the past few years. However, the progress shown…”
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Data, Reagents, Assays and Merits of Proteomics for SARS-CoV-2 Research and Testing by Zecha, Jana, Lee, Chien-Yun, Bayer, Florian P, Meng, Chen, Grass, Vincent, Zerweck, Johannes, Schnatbaum, Karsten, Michler, Thomas, Pichlmair, Andreas, Ludwig, Christina, Kuster, Bernhard

“…As the COVID-19 pandemic continues to spread, thousands of scientists around the globe have changed research direction to understand better how the virus works…”
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