Search Results - "Baybutt, Richard"
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Cod Liver Oil, but Not Retinoic Acid, Treatment Restores Bone Thickness in a Vitamin A-Deficient Rat
Published in Nutrients (22-01-2022)“…Vitamin A plays a prominent role for maintaining optimal bone status, but its impact upon the bone in response to vitamin A deficiency is not well defined. The…”
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Vitamin A depletion induced by cigarette smoke is associated with an increase in lung cancer-related markers in rats
Published in Journal of biomedical science (14-10-2015)“…We have previously demonstrated that cigarette smoke is associated with a significant reduction of retinoic acid in rat lungs and the formation of tracheal…”
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Lignans are involved in the antitumor activity of wheat bran in colon cancer SW480 cells
Published in The Journal of nutrition (01-03-2005)“…Wheat bran was shown to provide protection against colorectal cancer in human intervention and animal studies. Our recent study showed, however, that antitumor…”
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Reduced signaling of PI3K-Akt and RAS-MAPK pathways is the key target for weight-loss-induced cancer prevention by dietary calorie restriction and/or physical activity
Published in The Journal of nutritional biochemistry (01-12-2014)“…Weight control through either dietary calorie restriction (DCR) or exercise has been associated with cancer prevention in animal models. However, the…”
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Effects of Dietary Calorie Restriction or Exercise on the PI3K and Ras Signaling Pathways in the Skin of Mice
Published in The Journal of biological chemistry (21-09-2007)“…Weight control by exercise and dietary calorie restriction (DCR) has been associated with reduced cancer risk, but the underlying mechanisms are not well…”
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Effects on cytokines and histology by treatment with the ACE inhibitor captopril and the antioxidant retinoic acid in the monocrotaline model of experimentally induced lung fibrosis
Published in Current pharmaceutical design (01-05-2007)“…Monocrotaline (MCT), a pyrrolizidine alkaloid extracted from the shrub Crotalaria spectabilis, induces in the lungs of many mammalian species severe…”
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Vitamin A deficiency injures lung and liver parenchyma and impairs function of rat type II pneumocytes
Published in The Journal of nutrition (01-05-2000)“…The purpose of this research was to determine the effects of vitamin A deficiency on liver and lung morphology and type II pneumocyte function. Weanling rats…”
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Decreases in bone mineral content by dietary all-trans retinoic acid precede decreases in bone mineral density in a weanling rat model of cigarette smoke-induced lung injuries
Published in International journal for vitamin and nutrition research (01-01-2011)“…Research has indicated that excessive vitamin A can have deleterious impacts on bone. Retinoic acid (RA), the most active metabolite of vitamin A, has been…”
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proliferative effects of retinoic acid on primary cultures of adult rat type II pneumocytes depend upon cell density
Published in In vitro cellular & developmental biology. Animal (01-01-2010)“…Retinoic acid (RA) is important for maintaining integrity of alveolar epithelial cells, but the mechanism has not been defined. We cultured type II pneumocytes…”
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Dietary Flaxseed Oil Protects against Bleomycin-Induced Pulmonary Fibrosis in Rats
Published in Pulmonary Medicine (01-01-2012)“…Bleomycin, a widely used antineoplastic agent, has been associated with severe pulmonary toxicity, primarily fibrosis. Previous work has shown a reduction in…”
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Vitamin A depletion induced by cigarette smoke is associated with the development of emphysema in rats
Published in The Journal of nutrition (01-08-2003)“…We showed previously that vitamin A deficiency per se causes emphysema. Benzo(a)pyrene, a constituent in cigarette smoke, induces vitamin A depletion when…”
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Dietary fish oil protects against lung and liver inflammation and fibrosis in monocrotaline treated rats
Published in Toxicology (Amsterdam) (14-06-2002)“…The purpose of the present study was to evaluate the effectiveness of fish oil in preventing tissue pathologies associated with monocrotaline (MCT) toxicity…”
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Vitamin A and Emphysema
Published in Vitamin A (2007)“…Within the last several years, research scientists and clinicians have been intrigued with the potential use of an active form of vitamin A, retinoic acid…”
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Dietary β-carotene protects lung and liver parenchyma of rats treated with monocrotaline
Published in Toxicology (Amsterdam) (20-09-1999)“…Some studies have indicated that the injury induced by the hepato- and pneumotoxin monocrotaline (MCT) is in part mediated by oxidation. Because β-carotene is…”
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Type II pneumocytes modulate surfactant production in response to cigarette smoke constituents: Restoration by vitamins A and E
Published in Toxicology in vitro (01-12-2005)“…This study was to evaluate the effects of cigarette smoke constituents upon type II pneumocyte surfactant production in vitro, and how vitamins A and E may…”
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Skin Carotenoid Status Over Time and Differences by Age and Sex Among Head Start Children (3–5 Years)
Published in Journal of nutrition education and behavior (01-02-2021)“…Examine differences in skin carotenoid status (SCS) based on time, age, and sex of preschool-aged children enrolled in Head Start (HS) in North Carolina. Data…”
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Dietary retinol inhibits inflammatory responses of rats treated with monocrotaline
Published in The Journal of nutrition (01-07-1999)“…This study was designed to test the effectiveness of dietary retinol in protecting the heart and lung parenchyma in a monocrotaline model for lung injury and…”
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Deletion of Notch signaling in the developing mouse kidney results in a disruption of planar cell polarity in tubule epithelial cells
Published in The FASEB journal (01-04-2016)“…Abstract only Cux1 is the murine homologue of the Drosophila gene cut . In Drosophila, multiple genetic interactions between Cut and the Notch and Wingless…”
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Cux1 regulation of the cyclin kinase inhibitor p27kip1 in polycystic kidney disease is attenuated by HDAC inhibitors
Published in Gene (01-01-2019)“…Cux1 is a homeodomain protein involved in cell cycle regulation and kidney development. Cux1 represses the cyclin kinase inhibitor p27 during early kidney…”
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