Search Results - "Bayó, Nuria"

Combating virulence of Gram-negative bacilli by OmpA inhibition by Vila-Farrés, Xavier, Parra-Millán, Raquel, Sánchez-Encinales, Viviana, Varese, Monica, Ayerbe-Algaba, Rafael, Bayó, Nuria, Guardiola, Salvador, Pachón-Ibáñez, María Eugenia, Kotev, Martin, García, Jesús, Teixidó, Meritxell, Vila, Jordi, Pachón, Jerónimo, Giralt, Ernest, Smani, Younes

“…Preventing the adhesion of pathogens to host cells provides an innovative approach to tackling multidrug-resistant bacteria. In this regard, the identification…”
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AOA-2 Derivatives as Outer Membrane Protein A Inhibitors for Treatment of Gram-Negative Bacilli Infections by Ayerbe-Algaba, Rafael, Bayó, Nuria, Verdú, Ester, Parra-Millán, Raquel, Seco, Jesús, Teixidó, Meritxell, Pachón, Jerónimo, Giralt, Ernest, Smani, Younes

“…Previously, we identified that a cyclic hexapeptide AOA-2 inhibited the interaction of Gram-negative bacilli (GNB) like , , and to host cells thereby…”
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Synergistic activity of an OmpA inhibitor and colistin against colistin-resistant Acinetobacter baumannii: mechanistic analysis and in vivo efficacy by Parra-Millán, Raquel, Vila-Farrés, Xavier, Ayerbe-Algaba, Rafael, Varese, Monica, Sánchez-Encinales, Viviana, Bayó, Nuría, Pachón-Ibáñez, María Eugenia, Teixidó, Meritxell, Vila, Jordi, Pachón, Jerónimo, Giralt, Ernest, Smani, Younes

“…Preventing bacterial contact with host cells can provide an additional approach to tackling MDR Acinetobacter baumannii. Recently, we identified AOA-2 as a…”
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A new approach to 3-hydroxyquinoline-2-carboxylic acid by Riego, Estela, Bayó, Nuria, Cuevas, Carmen, Albericio, Fernando, Álvarez, Mercedes

“…Quinoline-2-carboxylic acid derivatives cap the N-terminal of several natural cyclic peptides with antitumoral activity. A new and convenient route for the…”
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Delivery of Nucleic Acids through the Controlled Disassembly of Multifunctional Nanocomplexes by Elsabahy, Mahmoud, Wazen, Nada, Bayó-Puxan, Núria, Deleavey, Glen, Servant, Marc, Damha, Masad J., Leroux, Jean-Christophe

“…In this study, novel pH‐responsive polyion complex micelles (PICMs) were developed for the efficient delivery of nucleic acid drugs, such as antisense…”
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Combined Use of Oligopeptides, Fragment Libraries, and Natural Compounds: A Comprehensive Approach To Sample the Druggability of Vascular Endothelial Growth Factor by Bayó-Puxan, Núria, Rodríguez-Mias, Ricard, Goldflam, Michael, Kotev, Martin, Ciudad, Sonia, Hipolito, Christopher J., Varese, Monica, Suga, Hiroaki, Campos-Olivas, Ramón, Barril, Xavier, Guallar, Víctor, Teixidó, Meritxell, García, Jesús, Giralt, Ernest

“…The modulation of protein–protein interactions (PPIs) is emerging as a highly promising tool to fight diseases. However, whereas an increasing number of…”
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Enzyme-Labile Protecting Groups for the Synthesis of Natural Products: Solid-Phase Synthesis of Thiocoraline by Tulla-Puche, Judit, Góngora-Benítez, Miriam, Bayó-Puxan, Núria, Francesch, Andrés M., Cuevas, Carmen, Albericio, Fernando

“…Another (orthogonal) dimension: The solid‐phase synthesis of thiocoraline was accomplished for the first time by a combined approach involving chemical and…”
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NMe Amide as a Synthetic Surrogate for the Thioester Moiety in Thiocoraline by Tulla-Puche, Judit, Marcucci, Eleonora, Prats-Alfonso, Elisabet, Bayó-Puxan, Núria, Albericio, Fernando

“…Bridged N-methyl amides are used as isosteres for depsi and thiodepsi bonds in thiocoraline. The introduction of NMe-amides in bridges mimics the thioester…”
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Oxathiocoraline: Lessons to be Learned from the Synthesis of Complex N‐Methylated Depsipeptides by Bayó‐Puxan, Núria, Tulla‐Puche, Judit, Albericio, Fernando

“…Investigations into the synthesis of oxathiocoraline, a bicyclic depsipeptide with C2 symmetry, revealed a number of unexpected side‐reactions that could not…”
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Solid-Phase Synthesis of Oxathiocoraline by a Key Intermolecular Disulfide Dimer by Tulla-Puche, Judit, Bayó-Puxan, Núria, Moreno, Juan A, Francesch, Andrés M, Cuevas, Carmen, Álvarez, Mercedes, Albericio, Fernando

“…Oxathiocoraline, a member of the quinoxaline antibiotic family, has been synthesized on solid-phase. The depsipeptide exhibits high synthetic complexity owing…”
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‘À La Carte’ Cyclic Hexapeptides: Fine Tuning Conformational Diversity while Preserving the Peptide Scaffold by Ciudad, Sonia, Bayó‐Puxán, Núria, Varese, Monica, Seco, Jesús, Teixidó, Meritxell, García, Jesús, Giralt, Ernest

“…Cyclic peptides have recently emerged as promising modulators of challenging protein‐protein interactions. Here we report on the design, synthesis and…”
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Protection by Conformationally Restricted Mobility: First Solid-Phase Synthesis of Triostin A by Tulla-Puche, Judit, Marcucci, Eleonora, Fermin, Manuel, Bayó-Puxan, Núria, Albericio, Fernando

“…Conformationally restricted mobility: The application of an efficient solid‐phase strategy based on protection by conformationally restricted mobility (see…”
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Total Solid-Phase Synthesis of the Azathiocoraline Class of Symmetric Bicyclic Peptides by Bayó-Puxan, Núria, Fernández, Ariadna, Tulla-Puche, Judit, Riego, Estela, Cuevas, Carmen, Álvarez, Mercedes, Albericio, Fernando

“…Thiocoraline is a potent antitumor agent isolated from the marine organism Micromonospora sp. This symmetric bicyclic depsipeptide binds the minor groove of…”
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Delivery of Nucleic Acids through the Controlled Disassembly of Multifunctional Nanocomplexes by Elsabahy, Mahmoud, Wazen, Nada, Bayó-Puxan, Núria, Deleavey, Glen, Servant, Marc, Damha, Masad J., Leroux, Jean-Christophe

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Preparation of polyion complex micelles from poly(ethylene glycol)- block-polyions by Bayó-Puxan, Núria, Dufresne, Marie-Hélène, Felber, Arnaud E., Castagner, Bastien, Leroux, Jean-Christophe

“…Polyion complex micelles (PICMs) arise from the spontaneous self-assembly of ionic polymers of opposite charges to form a condensate that is dispersed in…”
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The interactions of amphiphilic antisense oligonucleotides with serum proteins and their effects on in vitro silencing activity by Felber, Arnaud E, Bayó-Puxan, Núria, Deleavey, Glen F, Castagner, Bastien, Damha, Masad J, Leroux, Jean-Christophe

“…Abstract Antisense oligonucleotides (AONs) are a class of compounds with high therapeutic potential. One of the challenges facing this platform is the…”
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Beyond Azathiocoraline: Synthesis of Analogues by Bayó-Puxan, Núria, Fernández, Ariadna, Tulla-Puche, Judit, Riego, Estela, Álvarez, Mercedes, Albericio, Fernando

“…SummaryAzathiocoraline synthesis has been developed and optimized by using the solid-phase approach. This convenient solid-phase methodology, which involves…”
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Solid-Phase Synthesis of the Cyclic Lipononadepsipeptide [N-Mst(Ser1), D-Ser4, L-Thr6, L-Asp8, L-Thr9]Syringotoxin by Bayó, Nuria, Jiménez, Jose C., Rivas, Luis, Nicolás, Ernesto, Albericio, Fernando

“…An optimized solid‐phase strategy for the preparation of the cyclic lipononadepsipeptide [N‐Mst(L‐Ser1), D‐Ser4, L‐Thr6, L‐Asp8, L‐Thr9]syringotoxin is…”
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Enzyme-Labile Protecting Groups for the Synthesis of Natural Products: Solid-Phase Synthesis of Thiocoraline by Tulla-Puche, Judit, Góngora-Benítez, Miriam, Bayó-Puxan, Núria, Francesch, Andrés M., Cuevas, Carmen, Albericio, Fernando

“…Gut kombiniert! Durch eine Kombination aus chemischen und enzymatischen Methoden gelang erstmals die Festphasensynthese von Thiocoralin. Schlüsselschritte sind…”
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Chlorotrityl Chloride (CTC) Resin as a Reusable Carboxyl Protecting Group by García-Martín, Fayna, Bayó-Puxan, Núria, Cruz, Luis J., Bohling, James C., Albericio, Fernando

“…Chlorotrityl Chloride (CTC) resin is one of the most useful resins for the solid‐phase synthesis of C‐terminal acid peptides. CTC resin can be used for the…”
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