Search Results - "Baxter, Douglas"

How Can Memories Last for Days, Years, or a Lifetime? Proposed Mechanisms for Maintaining Synaptic Potentiation and Memory by Smolen, Paul, Baxter, Douglas A, Byrne, John H

“…With memory encoding reliant on persistent changes in the properties of synapses, a key question is how can memories be maintained from days to months or a…”
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Voltage- and Calcium-Gated Membrane Currents Tune the Plateau Potential Properties of Multiple Neuron Types by Neveu, Curtis L, Smolen, Paul, Baxter, Douglas A, Byrne, John H

“…Many neurons exhibit regular firing that is limited to the duration and intensity of depolarizing stimuli. However, some neurons exhibit all-or-nothing plateau…”
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ISiCLE: A Quantum Chemistry Pipeline for Establishing in Silico Collision Cross Section Libraries by Colby, Sean M, Thomas, Dennis G, Nuñez, Jamie R, Baxter, Douglas J, Glaesemann, Kurt R, Brown, Joseph M, Pirrung, Meg A, Govind, Niranjan, Teeguarden, Justin G, Metz, Thomas O, Renslow, Ryan S

“…High-throughput, comprehensive, and confident identifications of metabolites and other chemicals in biological and environmental samples will revolutionize our…”
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Application of double-focusing sector field ICP-MS for determination of ultratrace constituents in samples characterized by complex composition of the matrix by Rodushkin, Ilia, Paulukat, Cora, Pontér, Simon, Engström, Emma, Baxter, Douglas C., Sörlin, Dieke, Pallavicini, Nicola, Rodushkina, Katerina

“…The performance of double focusing, sector field mass spectrometry (ICP-SFMS) for determination of analytes, including technology critical elements (TCE), at…”
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Computational Model of the Distributed Representation of Operant Reward Memory: Combinatoric Engagement of Intrinsic and Synaptic Plasticity Mechanisms by Costa, Renan M, Baxter, Douglas A, Byrne, John H

“…Operant reward learning of feeding behavior in "Aplysia" increases the frequency and regularity of biting, as well as biases buccal motor patterns (BMPs)…”
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Molecular constraints on synaptic tagging and maintenance of long-term potentiation: a predictive model by Smolen, Paul, Baxter, Douglas A, Byrne, John H

“…Protein synthesis-dependent, late long-term potentiation (LTP) and depression (LTD) at glutamatergic hippocampal synapses are well characterized examples of…”
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Specific Plasticity Loci and Their Synergism Mediate Operant Conditioning by Momohara, Yuto, Neveu, Curtis L, Chen, Hsin-Mei, Baxter, Douglas A, Byrne, John H

“…Despite numerous studies examining the mechanisms of operant conditioning (OC), the diversity of OC plasticity loci and their synergism have not been examined…”
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Computational analysis of memory consolidation following inhibitory avoidance (IA) training in adult and infant rats: Critical roles of CaMKIIα and MeCP2 by Zhang, Yili, Smolen, Paul, Alberini, Cristina M., Baxter, Douglas A., Byrne, John H.

“…Key features of long-term memory (LTM), such as its stability and persistence, are acquired during processes collectively referred to as consolidation. The…”
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Sources of contamination and remedial strategies in the multi-elemental trace analysis laboratory by Rodushkin, Ilia, Engström, Emma, Baxter, Douglas C

“…In theory, state of the art inductively coupled plasma mass spectrometry (ICP-MS) instrumentation has the prerequisite sensitivity to carry out multi-elemental…”
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Paradoxical LTP maintenance with inhibition of protein synthesis and the proteasome suggests a novel protein synthesis requirement for early LTP reversal by Smolen, Paul, Baxter, Douglas A., Byrne, John H.

“…•Late LTP is not blocked when protein synthesis and degradation are inhibited together.•To investigate this paradox, we developed a minimal model describing…”
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Inferring neuronal network functional connectivity with directed information by Cai, Zhiting, Neveu, Curtis L, Baxter, Douglas A, Byrne, John H, Aazhang, Behnaam

“…A major challenge in neuroscience is to develop effective tools that infer the circuit connectivity from large-scale recordings of neuronal activity patterns…”
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Modeling suggests combined-drug treatments for disorders impairing synaptic plasticity via shared signaling pathways by Smolen, Paul, Wood, Marcelo A., Baxter, Douglas A., Byrne, John H.

“…Genetic disorders such as Rubinstein-Taybi syndrome (RTS) and Coffin-Lowry syndrome (CLS) cause lifelong cognitive disability, including deficits in learning…”
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ScalaBLAST 2.0: rapid and robust BLAST calculations on multiprocessor systems by Oehmen, Christopher S, Baxter, Douglas J

“…BLAST remains one of the most widely used tools in computational biology. The rate at which new sequence data is available continues to grow exponentially,…”
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Simultaneous measurements of As, Mo, Sb, V and W using a ferrihydrite diffusive gradients in thin films (DGT) device by Österlund, Heléne, Chlot, Sara, Faarinen, Mikko, Widerlund, Anders, Rodushkin, Ilia, Ingri, Johan, Baxter, Douglas C.

“…The ferrihydrite-backed DGT (diffusive gradients in thin films), recently developed for arsenic and phosphate measurements was, for the first time,…”
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Computational analyses of synergism in small molecular network motifs by Zhang, Yili, Smolen, Paul, Baxter, Douglas A, Byrne, John H

“…Cellular functions and responses to stimuli are controlled by complex regulatory networks that comprise a large diversity of molecular components and their…”
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Comparing Theories for the Maintenance of Late LTP and Long-Term Memory: Computational Analysis of the Roles of Kinase Feedback Pathways and Synaptic Reactivation by Smolen, Paul, Baxter, Douglas A, Byrne, John H

“…A fundamental neuroscience question is how memories are maintained from days to a lifetime, given turnover of proteins that underlie expression of long-term…”
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Computational design of enhanced learning protocols by Zhang, Yili, Liu, Rong-Yu, Heberton, George A, Smolen, Paul, Baxter, Douglas A, Cleary, Leonard J, Byrne, John H

“…The authors use computational modeling to design an optimized learning protocol that takes into account the precise timing of molecular signaling cascades that…”
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Temporal isotopic variations of dissolved silicon in a pristine boreal river by Engström, Emma, Rodushkin, Ilia, Ingri, Johan, Baxter, Douglas C., Ecke, Frauke, Österlund, Heléne, Öhlander, Björn

“…It has previously been concluded that the stable Si isotopes are fractionated during geochemical and biogeochemical elemental transfers, such as weathering and…”
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Computational Model of a Positive BDNF Feedback Loop in Hippocampal Neurons Following Inhibitory Avoidance Training by Zhang, Yili, Smolen, Paul, Alberini, Cristina M, Baxter, Douglas A, Byrne, John H

“…Inhibitory avoidance (IA) training in rodents initiates a molecular cascade within hippocampal neurons. This cascade contributes to the transition of short- to…”
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Molecular Mechanisms Underlying a Cellular Analog of Operant Reward Learning by Lorenzetti, Fred D., Baxter, Douglas A., Byrne, John H.

“…Operant conditioning is a ubiquitous but mechanistically poorly understood form of associative learning in which an animal learns the consequences of its…”
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