Search Results - "Baxter, Alex"

The effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection): a randomised placebo-controlled trial by Baigent, Colin, Prof, Landray, Martin J, FRCP, Reith, Christina, MRCP, Emberson, Jonathan, PhD, Wheeler, David C, FRCP, Tomson, Charles, DM, Wanner, Christoph, Prof, Krane, Vera, MD, Cass, Alan, Prof, Craig, Jonathan, Prof, Neal, Bruce, Prof, Jiang, Lixin, MD, Hooi, Lai Seong, FRCP, Levin, Adeera, Prof, Agodoa, Lawrence, Prof, Gaziano, Mike, Prof, Kasiske, Bertram, Prof, Walker, Robert, Prof, Massy, Ziad A, Prof, Feldt-Rasmussen, Bo, Prof, Krairittichai, Udom, MD, Ophascharoensuk, Vuddidhej, MD, Fellström, Bengt, Prof, Holdaas, Hallvard, MD, Tesar, Vladimir, Prof, Wiecek, Andrzej, Prof, Grobbee, Diederick, Prof, de Zeeuw, Dick, Prof, Grönhagen-Riska, Carola, Prof, Dasgupta, Tanaji, MRCP, Lewis, David, MRCP, Herrington, William, MRCP, Mafham, Marion, MD, Majoni, William, FRACP, Wallendszus, Karl, MSc, Grimm, Richard, Prof, Pedersen, Terje, Prof, Tobert, Jonathan, PhD, Armitage, Jane, Prof, Baxter, Alex, BA, Bray, Christopher, PhD, Chen, Yiping, DPhil, Chen, Zhengming, Prof, Hill, Michael, DPhil, Knott, Carol, MSc, Parish, Sarah, DPhil, Simpson, David, Sleight, Peter, Prof, Young, Alan, DPhil, Collins, Rory, Prof

“…Summary Background Lowering LDL cholesterol with statin regimens reduces the risk of myocardial infarction, ischaemic stroke, and the need for coronary…”
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Effects of Lowering LDL Cholesterol on Progression of Kidney Disease by HAYNES, Richard, LEWIS, David, LEVIN, Adeera, WHEELER, David C, WALKER, Rob, HERRINGTON, William G, BAIGENT, Colin, LANDRAY, Martin J, EMBERSON, Jonathan, REITH, Christina, AGODOA, Lawrence, CASS, Alan, CRAIG, Jonathan C, DE ZEEUW, Dick, FELDT-RASMUSSEN, Bo, FELLSTRÖM, Bengt

“…Lowering LDL cholesterol reduces the risk of developing atherosclerotic events in CKD, but the effects of such treatment on progression of kidney disease…”
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First United Kingdom Heart and Renal Protection (UK-HARP-I) study: Biochemical efficacy and safety of simvastatin and safety of low-dose aspirin in chronic kidney disease by Baigent, Colin, Landray, Martin, Leaper, Craig, Altmann, Paul, Armitage, Jane, Baxter, Alex, Cairns, Hugh S., Collins, Rory, Foley, Robert N., Frighi, Valeria, Kourellias, Karen, Ratcliffe, Peter J., Rogerson, Mary, Scoble, John E., Tomson, Charles R.V., Wheeler, David C., Warwick, Graham

“…Background: Patients with chronic kidney disease are at increased risk for cardiovascular disease, but the efficacy and safety of simvastatin and aspirin are…”
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Functional neurological disorder in children and young people: Incidence, clinical features, and prognosis by Yong, Kenneith, Chin, Richard F. M., Shetty, Jay, Hogg, Kirsty, Burgess, Kieran, Lindsay, Max, McLellan, Ailsa, Stone, Jon, KamathTallur, Krishnaraya, Baxter, Alex, McWilliam, Kenneth, Pilley, Elizabeth

“…Aim To report incidence, demographic and clinical characteristics, and symptom outcome of functional neurological disorder (FND) in children. Method Children…”
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Aspirin in the primary and secondary prevention of vascular disease: collaborative meta-analysis of individual participant data from randomised trials by Baigent, Colin, Blackwell, Lisa, Collins, Rory, Emberson, Jonathan, Godwin, Jon, Peto, Richard, Buring, Julie, Hennekens, Charles, Kearney, Patricia, Meade, Tom, Patrono, Carlo, Roncaglioni, Maria Carla, Zanchetti, Alberto

“…Summary Background Low-dose aspirin is of definite and substantial net benefit for many people who already have occlusive vascular disease. We have assessed…”
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Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial by Shakur, Haleema, Roberts, Ian, Bautista, Raúl, Caballero, José, Coats, Tim, Dewan, Yashbir, El-Sayed, Hesham, Gogichaishvili, Tamar, Gupta, Sanjay, Herrera, Jorge, Hunt, Beverley, Iribhogbe, Pius, Izurieta, Mario, Khamis, Hussein, Komolafe, Edward, Marrero, María-Acelia, Mejía-Mantilla, Jorge, Miranda, Jaime, Morales, Carlos, Olaomi, Oluwole, Olldashi, Fatos, Perel, Pablo, Peto, Richard, Ramana, P V, Ravi, R R, Yutthakasemsunt, Surakrant

“…Summary Background Tranexamic acid can reduce bleeding in patients undergoing elective surgery. We assessed the effects of early administration of a short…”
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Fractures and bone health monitoring in boys with Duchenne muscular dystrophy managed within the Scottish Muscle Network by Joseph, Shuko, Wang, Cunyi, Di Marco, Marina, Horrocks, Iain, Abu-Arafeh, Ishaq, Baxter, Alex, Cordeiro, Nuno, McLellan, Linda, McWilliam, Kenneth, Naismith, Karen, Stephen, Elma, Ahmed, S. Faisal, Wong, Sze Choong

“…•A high rate of radiologically confirmed symptomatic fractures (48%) was identified.•Non-vertebral fractures occurred predominantly at femur and tibia after…”
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Peak functional ability and age at loss of ambulation in Duchenne muscular dystrophy by Zambon, Alberto A., Ayyar Gupta, Vandana, Ridout, Deborah, Manzur, Adnan Y., Baranello, Giovanni, Trucco, Federica, Muntoni, Francesco, Tirupath, Sandya, Douglas, Melanie, McFetridge, Jaci, Parasuraman, Deepak, Alhaswani, Zoya, McMurchie, Heather, Rabb, Rosanna, Majumdar, Anirban, Vijayakumar, Kayal, Amin, Sam, Mason, Faye, Frimpong‐Ansah, Claire, Gibbon, Frances, Parson, Bethan, Naismith, Karen, Burslem, Julie, Baxter, Alex, Eadie, Clare, Horrocks, Iain, Di Marco, Marina, Childs, Anne‐Marie, Pallant, Lindsey, Spinty, Stefan, Shillington, Alison, Gregson, Sarah, Cheshman, Laura, Wraige, Elizabeth, Gowda, Vasantha, Jungbluth, Heinz, Sheehan, Jennie, Hughes, Imelda, Warner, Sinead, Straub, Volker, Guglieri, Michela, Mayhew, Anna, Chow, Gabby, Williamson, Sarah, Willis, Tracey, Kulshrestha, Richa, Emery, Nicholas, Ramdas, Sithara, Ramjattan, Hayley, de Goede, Christian, Selley, Andrea, Ong, Min, White, Kay, Illingworth, Marjorie, Geary, Michelle, Palmer, Jenni, White, Cathy, Greenfield, Kate, Hewawitharana, Gemunu, Julien, Yvonne, Stephens, Elma, Tewnion, Jane, Ambegaonkar, Gautam, Krishnakumar, Deepa, Taylor, Jacqui, Ward, Catherine, Willis, Tracey, Wright, Elizabeth, Rylance, Claire

“…Aim To correlate the North Star Ambulatory Assessment (NSAA) and timed rise from floor (TRF) recorded at age of expected peak with age at loss of ambulation…”
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Smoking and Adverse Outcomes in Patients With CKD: The Study of Heart and Renal Protection (SHARP) by Staplin, Natalie, PhD, Haynes, Richard, DM, Herrington, William G., MD, Reith, Christina, FRCP, Cass, Alan, FRACP, Fellström, Bengt, MD, Jiang, Lixin, MD, Kasiske, Bertram L., MD, Krane, Vera, MD, Levin, Adeera, FRCPC, Walker, Robert, FRACP, Wanner, Christoph, MD, Wheeler, David C., FRCP, Landray, Martin J., PhD, Baigent, Colin, FRCP, Emberson, Jonathan, PhD

“…Background The absolute and relative importance of smoking to vascular and nonvascular outcomes in people with chronic kidney disease (CKD), as well its…”
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Design, recruitment and baseline characteristics of the LENS trial by Preiss, David, Logue, Jennifer, Zayed, Mohammed, Emberson, Jon, Wallendszus, Karl, Stevens, Will, Harding, Simon, Armitage, Jane, Williamson, Paula, Cairns, Allan, Adigwe, Gozie Joe, Lyons, Timothy, Mackenzie, Isla, Young, Ian, Staplin, Natalie, Sawyer, Kate, Taylor, Karen, Achiri, Patricia, Burke, Andy, Hurley, Susan, McChlery, Gareth, Murphy, Kevin, Pickworth, Sandra, Vandenberg, Kate, Willett, Monique, Beesley, Matthew, Roure, Ian, Bagley, Graham, Whitehouse, Anne, Young, Isobel, Brown, Gavin, Bird, Kate, Cretney, Rosanna, Cui, Guanguo, Daniels, Charles, Field, Angela, Syed, Samee, Chamberlain, Angela, Meek, Juliette, Wilson, Andrea, Zettegren, Patrick, Barton, Ian, Thompson, James, Spata, Enti, Howard, Crispian, Connelly, Paul, Varikkara, Mohan, Locke, Jacqueline, Herlihy, Olive, Bell, Ewan, Boytha, Susan, Neill, Paula, Styles, Caroline, Blaikie, Andrew, Beveridge, Laura, Fowler, Susan, Lister, Linda, McGregor, Amanda, Pirie, Sandra, White, Anna, Doig, John, Brogan, Stephanie, Duncan, Margie, Gilmour, Angela, Todd, Anne, Philip, Sam, Cadzow, Ann, Murray, Lynne, Toye, Julie, Zachariah, Sonia, Bailey, Lindsey, Begg, Alison, Brown, Katherine, Duffy, Katharine, Gill, Adam, Jenkins, David, Martin, Laila, McAllister, Christine, MciIntyre, Mhairi, Milne, Leeanne, Peddie, Hilary, Speirs, Susan, Thompson, Joyce, Finlayson, Jim, Virdi, Meena, Park, Soo, Brown, Maureen, Macliver, Linda, Quigley, Jackie, Madill, Karen, Burgess, Freddie, McDonald, Margaret, Sedstrem, Karen, Thomson, Alice, Malcolm, Ellen, Lindsay, Jackie, Colhoun, Helen, Lindsay, Robert, Sattar, Naveed, Scotland, Graham

“…Background Findings from cardiovascular outcome trials suggest that treatment with fenofibrate may reduce the progression of diabetic retinopathy. However, no…”
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Lowering LDL cholesterol reduces cardiovascular risk independently of presence of inflammation by Storey, Benjamin C, Staplin, Natalie, Haynes, Richard, Reith, Christina, Emberson, Jonathan, Herrington, William G, Wheeler, David C, Walker, Robert, Fellström, Bengt, Wanner, Christoph, Landray, Martin J, Baigent, Colin

“…Markers of inflammation, including plasma C-reactive protein (CRP), are associated with an increased risk of cardiovascular disease, and it has been suggested…”
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Efficacy and Safety of Vamorolone in Duchenne Muscular Dystrophy: A 30-Month Nonrandomized Controlled Open-Label Extension Trial by Mah, Jean K, Clemens, Paula R, Guglieri, Michela, Smith, Edward C, Finkel, Richard S, Tulinius, Mar, Nevo, Yoram, Ryan, Monique M, Webster, Richard, Castro, Diana, Kuntz, Nancy L, McDonald, Craig M, Damsker, Jesse M, Schwartz, Benjamin D, Mengle-Gaw, Laurel J, Jackowski, Stefan, Stimpson, Georgia, Ridout, Deborah A, Ayyar-Gupta, Vandana, Baranello, Giovanni, Manzur, Adnan Y, Muntoni, Francesco, Gordish-Dressman, Heather, Leinonen, Mika, Ward, Leanne M, Hoffman, Eric P, Dang, Utkarsh J

“…Vamorolone is a synthetic steroidal drug with potent anti-inflammatory properties. Initial open-label, multiple ascending dose-finding studies of vamorolone…”
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Growth pattern trajectories in boys with Duchenne muscular dystrophy by Stimpson, Georgia, Raquq, Sarah, Chesshyre, Mary, Fewtrell, Mary, Ridout, Deborah, Sarkozy, Anna, Manzur, Adnan, Ayyar Gupta, Vandana, De Amicis, Ramona, Muntoni, Francesco, Baranello, Giovanni

“…The objective of this study is to analyse retrospective, observational, longitudinal growth (weight, height and BMI) data in ambulatory boys aged 5-12 years…”
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The Second United Kingdom Heart and Renal Protection (UK-HARP-II) Study: A Randomized Controlled Study of the Biochemical Safety and Efficacy of Adding Ezetimibe to Simvastatin as Initial Therapy Among Patients With CKD by Landray, Martin, Baigent, Colin, Leaper, Craig, Adu, Dwomoa, Altmann, Paul, Armitage, Jane, Ball, Simon, Baxter, Alex, Blackwell, Lisa, Cairns, Hugh S., Carr, Sue, Collins, Rory, Kourellias, Karen, Rogerson, Mary, Scoble, John E., Tomson, Charles R.V., Warwick, Graham, Wheeler, David C.

“…Background: Evaluating the effects of decreasing low-density lipoprotein (LDL) cholesterol levels requires large randomized trials. In preparation for such a…”
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The effect of lowering LDL cholesterol on vascular access patency: post hoc analysis of the Study of Heart and Renal Protection by Herrington, William, Emberson, Jonathan, Staplin, Natalie, Blackwell, Lisa, Fellström, Bengt, Walker, Robert, Levin, Adeera, Hooi, Lai Seong, Massy, Ziad A, Tesar, Vladimir, Reith, Christina, Haynes, Richard, Baigent, Colin, Landray, Martin J

“…Reducing LDL cholesterol (LDL-C) with statin-based therapy reduces the risk of major atherosclerotic events among patients with CKD, including dialysis…”
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Positive impact of Tai Chi Chuan participation on biopsychosocial quality of life compared to exercise and sedentary controls: a cross-sectional survey by Baxter, Alex, J P Francis, Andrew

“…Tai Chi Chuan (TCC) is a traditional Chinese medicine practice and martial art with biopsychosocial aspects. This study aimed to examine the impact of…”
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Campath, calcineurin inhibitor reduction and chronic allograft nephropathy (3C) study: background, rationale, and study protocol by Haynes, Richard, Baigent, Colin, Harden, Paul, Landray, Martin, Akyol, Murat, Asderakis, Argiris, Baxter, Alex, Bhandari, Sunil, Chowdhury, Paramit, Clancy, Marc, Emberson, Jonathan, Gibbs, Paul, Hammad, Abdul, Herrington, Will, Jayne, Kathy, Jones, Gareth, Krishnan, Nithya, Lay, Michael, Lewis, David, Macdougall, Iain, Nathan, Chidambaram, Neuberger, James, Newstead, Chas, Pararajasingam, Ravi, Puliatti, Carmelo, Rigg, Keith, Rowe, Peter, Sharif, Adnan, Sheerin, Neil, Sinha, Sanjay, Watson, Chris, Friend, Peter

“…Kidney transplantation is the best treatment for patients with end-stage renal failure, but uncertainty remains about the best immunosuppression strategy…”
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