Search Results - "Bawden, L J"

Inhibition of tumour growth by marimastat in a human xenograft model of gastric cancer: relationship with levels of circulating CEA by WATSON, S. A, MORRIS, T. M, COLLINS, H. M, BAWDEN, L. J, HAWKINS, K, BONE, E. A

“…Inhibition of matrix metalloproteinases (MMPs) is an attractive approach to adjuvant therapy in the treatment of cancer. Marimastat is the first orally…”
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Inhibition of the metastatic spread and growth of B16-BL6 murine melanoma by a synthetic matrix metalloproteinase inhibitor by Chirivi, R G, Garofalo, A, Crimmin, M J, Bawden, L J, Stoppacciaro, A, Brown, P D, Giavazzi, R

“…The synthetic matrix metalloproteinase inhibitor batimastat was tested for its ability to inhibit growth and metastatic spread of the B16-BL6 murine melanoma…”
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Two PDGF‐B chain residues, arginine 27 and isoleucine 30, mediate receptor binding and activation by Clements, J.M., Bawden, L.J., Bloxidge, R.E., Catlin, G., Cook, A.L., Craig, S., Drummond, A.H., Edwards, R.M., Fallon, A., Green, D.R.

“…PDGF may be involved in the pathogenesis of a variety of disorders including atherosclerosis and certain types of cancer. There is currently little…”
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Purification and analysis of proteinase-resistant mutants of recombinant platelet-derived growth factor-BB exhibiting improved biological activity by COOK, A. L, KIRWIN, P. M, CLEMENTS, J. M, CRAIG, S, BAWDEN, L. J, GREEN, D. R, PRICE, M. J, RICHARDSON, S. J, FALLON, A, DRUMMOND, A. H, EDWARDS, R. M

“…Recombinant platelet-derived growth factor (PDGF)-BB was expressed and secreted from yeast in order to study the structure-function relationships of this…”
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The antiproliferative activity of interferons assayed by measuring growth medium color changes related to cell number by Dawson, K M, Bawden, L J, Featherstone, D A

“…A simple colorimetric assay for estimating cell numbers has been developed based on the observation that the indicator color in cell culture medium is…”
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