Search Results - "Bawa, Bhupinder"

Potential mechanisms of target-independent uptake and toxicity of antibody-drug conjugates by Mahalingaiah, Prathap Kumar, Ciurlionis, Rita, Durbin, Kenneth R., Yeager, Ronnie L., Philip, Binu K., Bawa, Bhupinder, Mantena, Srinivasa R., Enright, Brian P., Liguori, Michael J., Van Vleet, Terry R.

“…Antibody-drug conjugates (ADCs) are a promising therapeutic modality for oncology indications. The concept of an ADC platform is to increase the therapeutic…”
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An Intact Sialoadhesin (Sn/SIGLEC1/CD169) Is Not Required for Attachment/Internalization of the Porcine Reproductive and Respiratory Syndrome Virus by Prather, Randall S, Rowland, Raymond R R, Ewen, Catherine, Trible, Benjamin, Kerrigan, Maureen, Bawa, Bhupinder, Teson, Jennifer M, Mao, Jiude, Lee, Kiho, Samuel, Melissa S, Whitworth, Kristin M, Murphy, Clifton N, Egen, Tina, Green, Jonathan A

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Impacts of different expressions of PA-X protein on 2009 pandemic H1N1 virus replication, pathogenicity and host immune responses by Lee, Jinhwa, Yu, Hai, Li, Yonghai, Ma, Jingjiao, Lang, Yuekun, Duff, Michael, Henningson, Jamie, Liu, Qinfang, Li, Yuhao, Nagy, Abdou, Bawa, Bhupinder, Li, Zejun, Tong, Guangzhi, Richt, Juergen A, Ma, Wenjun

“…Abstract Although several studies have investigated the functions of influenza PA-X, the impact of different expressions of PA-X protein including full-length,…”
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Combination of PB2 271A and SR Polymorphism at Positions 590/591 Is Critical for Viral Replication and Virulence of Swine Influenza Virus in Cultured Cells and In Vivo by QINFANG LIU, CHUANLING QIAO, MARJUKI, Henju, BAWA, Bhupinder, JINGQUN MA, GUILLOSSOU, Stephane, WEBBY, Richard J, RICHT, Jürgen A, WENJUN MA

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Characterization of uncultivable bat influenza virus using a replicative synthetic virus by Zhou, Bin, Ma, Jingjiao, Liu, Qinfang, Bawa, Bhupinder, Wang, Wei, Shabman, Reed S, Duff, Michael, Lee, Jinhwa, Lang, Yuekun, Cao, Nan, Nagy, Abdou, Lin, Xudong, Stockwell, Timothy B, Richt, Juergen A, Wentworth, David E, Ma, Wenjun

“…Bats harbor many viruses, which are periodically transmitted to humans resulting in outbreaks of disease (e.g., Ebola, SARS-CoV). Recently, influenza…”
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Neural cell proliferation and survival in the hippocampus of adult CaV 2.1 calcium ion channel mutant mice by Nigussie, Fikru, Huang, Pei-San, Lukauskis, Kris, Bawa, Bhupinder, Moussa, Eid, Abbott, Louise C

“…Abstract Tottering mutant mice carry a mutation in the pore-forming subunit (α1A) of CaV 2.1 (P/Q-type) voltage-gated calcium ion (Ca2+ ) channels resulting in…”
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Deep Learning Approaches and Applications in Toxicologic Histopathology: Current Status and Future Perspectives by Mehrvar, Shima, Himmel, Lauren E., Babburi, Pradeep, Goldberg, Andrew L., Guffroy, Magali, Janardhan, Kyathanahalli, Krempley, Amanda L., Bawa, Bhupinder

“…Whole slide imaging enables the use of a wide array of digital image analysis tools that are revolutionizing pathology. Recent advances in digital pathology…”
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Analysis of Calcium Ion homeostasis and mitochondrial function in cerebellar granule cells of adult Cav 2.1 Calcium Ion channel mutant mice by Bawa, Bhupinder, Abbott, Louise C.

“…Ca v 2.1 voltage-gated calcium channels (VGCC) are highly expressed by cerebellar neurons, and their dysfunction is linked to human disorders including…”
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Changes in Biochemical Processes in Cerebellar Granule Cells of Mice Exposed To Methylmercury by Bellum, Sairam, Bawa, Bhupinder, Thuett, Kerry A., Stoica, Gheorghe, Abbott, Louise C.

“…At postnatal day 34, male and female C57BL/6J mice were exposed orally once a day to a total of five doses totaling 1.0 or 5.0 mg/kg of methylmercuric chloride…”
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Newcastle Disease Virus-Vectored H7 and H5 Live Vaccines Protect Chickens from Challenge with H7N9 or H5N1 Avian Influenza Viruses by Liu, Qinfang, Mena, Ignacio, Ma, Jingjiao, Bawa, Bhupinder, Krammer, Florian, Lyoo, Young S, Lang, Yuekun, Morozov, Igor, Mahardika, Gusti Ngurah, Ma, Wenjun, García-Sastre, Adolfo, Richt, Juergen A

“…Sporadic human infections by a novel H7N9 virus occurred over a large geographic region in China. In this study, we show that Newcastle disease virus…”
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NSAIDs inhibit cell migration and calpain expression in rat duodenum (784.1) by Silver, Kristopher, Bawa, Bhupinder, Lillich, James

“…Nonsteroidal anti‐inflammatory drugs (NSAIDs) are one of the most commonly used drugs for the alleviation of pain and inflammation. Unfortunately, daily use of…”
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Results of the European Society of Toxicologic Pathology Survey on the Use of Artificial Intelligence in Toxicologic Pathology by Palazzi, Xavier, Barale-Thomas, Erio, Bawa, Bhupinder, Carter, Jonathan, Janardhan, Kyathanahalli, Marxfeld, Heike, Nyska, Abraham, Saravanan, Chandrassegar, Schaudien, Dirk, Schumacher, Vanessa L., Spaet, Robert H., Tangermann, Simone, Turner, Oliver C, Vezzali, Enrico

“…The European Society of Toxicologic Pathology (ESTP) initiated a survey through its Pathology 2.0 workstream in partnership with sister professional societies…”
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Domestic pigs are susceptible to infection with influenza B viruses by Ran, Zhiguang, Shen, Huigang, Lang, Yuekun, Kolb, Elizabeth A, Turan, Nuri, Zhu, Laihua, Ma, Jingjiao, Bawa, Bhupinder, Liu, Qinfang, Liu, Haixia, Quast, Megan, Sexton, Gabriel, Krammer, Florian, Hause, Ben M, Christopher-Hennings, Jane, Nelson, Eric A, Richt, Juergen, Li, Feng, Ma, Wenjun

“…Influenza B virus (IBV) causes seasonal epidemics in humans. Although IBV has been isolated from seals, humans are considered the primary host and reservoir of…”
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Society of Toxicologic Pathology Digital Pathology and Image Analysis Special Interest Group Article: Opinion on the Application of Artificial Intelligence and Machine Learning to Digital Toxicologic Pathology by Turner, Oliver C., Aeffner, Famke, Bangari, Dinesh S., High, Wanda, Knight, Brian, Forest, Tom, Cossic, Brieuc, Himmel, Lauren E., Rudmann, Daniel G., Bawa, Bhupinder, Muthuswamy, Anantharaman, Aina, Olulanu H., Edmondson, Elijah F., Saravanan, Chandrassegar, Brown, Danielle L., Sing, Tobias, Sebastian, Manu M.

“…Toxicologic pathology is transitioning from analog to digital methods. This transition seems inevitable due to a host of ongoing social and medical…”
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Suppression of Calpain Expression by NSAIDs is Associated with Inhibition of Cell Migration in Rat Duodenum by Silver, Kristopher, Littlejohn, A, Thomas, Laurel, Bawa, Bhupinder, Lillich, James D

“…Highlights • Suppression of calpain protein expression with siRNA inhibited IEC-6 cell migration. • NSAIDs, but not calpain siRNA, suppressed calpain activity…”
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Description of a novel fatigue syndrome of finished feedlot cattle following transportation by Thomson, Daniel U, Loneragan, Guy H, Henningson, Jamie N, Ensley, Steve, Bawa, Bhupinder

“…Ensuring appropriate animal welfare is a high priority for the beef industry, and poorly defined abnormalities in the mobility of cattle at abattoirs have…”
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Urinary MicroRNA biomarkers of nephrotoxicity in Macaca fascicularis by Dasgupta, Subham, Sharapova, Tatiana, Mahalingaiah, Prathap K., Chorley, Brian N., Shoieb, Ahmed, Tsuji, Takayuki, dos Santos, Alef A.C., Chari, Rohit, Ebrahimi, Ali, Dalmas Wilk, Deidre A., Pettit, Syril, Bawa, Bhupinder, Vaughan, Erin, van Vleet, Terry R., Mitchell, Constance A., Yuen, Peter S.T.

“…Drug-induced kidney injury (DIKI) refers to kidney damage resulting from the administration of medications. The aim of this project was to identify reliable…”
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Analysis of recombinant H7N9 wild-type and mutant viruses in pigs shows that the Q226L mutation in HA is important for transmission by Liu, Qinfang, Zhou, Bin, Ma, Wenjun, Bawa, Bhupinder, Ma, Jingjiao, Wang, Wei, Lang, Yuekun, Lyoo, Young, Halpin, Rebecca A, Lin, Xudong, Stockwell, Timothy B, Webby, Richard, Wentworth, David E, Richt, Juergen A

“…The fact that there have been more than 300 human infections with a novel avian H7N9 virus in China indicates that this emerging strain has pandemic potential…”
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Pathogenicity and transmissibility of novel reassortant H3N2 influenza viruses with 2009 pandemic H1N1 genes in pigs by Ma, Jingjiao, Shen, Huigang, Liu, Qinfang, Bawa, Bhupinder, Qi, Wenbao, Duff, Michael, Lang, Yuekun, Lee, Jinhwa, Yu, Hai, Bai, Jianfa, Tong, Guangzhi, Hesse, Richard A, Richt, Jürgen A, Ma, Wenjun

“…At least 10 different genotypes of novel reassortant H3N2 influenza viruses with 2009 pandemic H1N1 [A(H1N1)pdm09] gene(s) have been identified in U.S. pigs,…”
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A Recombinant Rift Valley Fever Virus Glycoprotein Subunit Vaccine Confers Full Protection against Rift Valley Fever Challenge in Sheep by Faburay, Bonto, Wilson, William C., Gaudreault, Natasha N., Davis, A. Sally, Shivanna, Vinay, Bawa, Bhupinder, Sunwoo, Sun Young, Ma, Wenjun, Drolet, Barbara S., Morozov, Igor, McVey, D. Scott, Richt, Juergen A.

“…Rift Valley fever virus (RVFV) is a mosquito-borne zoonotic pathogen causing disease outbreaks in Africa and the Arabian Peninsula. The virus has great…”
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