Search Results - "Bavari, S"

Risk assessment and quantitative measurement along with monitoring of Legionella in hospital water sources by Bavari, S., Mirkalantari, S., Masjedian Jazi, F., Darban-Sarokhalil, D., Golnari Marani, B.

“…Legionella spp. as a causative agent of Legionnaires' disease (LD) and an opportunistic pathogen creates a public health problem. Isolation and quantification…”
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Considerations for the development of Zika virus vaccines by Martins, K.A.O, Dye, J.M, Bavari, S

“…The authors observed that successive exposure to closely related viral variants induced a preferential response to the initially encountered variant. [...]with…”
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Association of Bacillus anthracis Capsule with Lethal Toxin during Experimental Infection by EZZELL, J. W, ABSHIRE, T. G, PANCHAL, R, CHABOT, D, BAVARI, S, LEFFEL, E. K, PURCELL, B, FRIEDLANDER, A. M, RIBOT, W. J

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Pharmacophore-guided lead optimization: The rational design of a non-zinc coordinating, sub-micromolar inhibitor of the botulinum neurotoxin serotype a metalloprotease by Burnett, J.C., Wang, C., Nuss, J.E., Nguyen, T.L., Hermone, A.R., Schmidt, J.J., Gussio, R., Wipf, P., Bavari, S.

“…The 3-zone pharmacophore for botulinum neurotoxin serotype A metalloprotease inhibition guided the design of a potent regioisomeric pair possessing a K i = 600…”
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Application of carbohydrate microarray technology for the detection of Burkholderia pseudomallei, Bacillus anthracis and Francisella tularensis antibodies by Parthasarathy, N., Saksena, R., Kováč, P., DeShazer, D., Peacock, S.J., Wuthiekanun, V., Heine, H.S., Friedlander, A.M., Cote, C.K., Welkos, S.L., Adamovicz, J.J., Bavari, S., Waag, D.M.

“…We developed a microarray platform by immobilizing bacterial ‘signature’ carbohydrates onto epoxide modified glass slides. The carbohydrate microarray platform…”
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Macrophage-Derived Cell Lines Do Not Express Proinflammatory Cytokines after Exposure to Bacillus anthracis Lethal Toxin by ERWIN, James L, DASILVA, Luis M, BAVARI, Sina, LITTLE, Stephen F, FRIEDLANDER, Arthur M, CHANH, Tran C

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Toxicity of staphylococcal enterotoxins potentiated by lipopolysaccharide: major histocompatibility complex class II molecule dependency and cytokine release by Stiles, B G, Bavari, S, Krakauer, T, Ulrich, R G

“…The biological effects of staphylococcal enterotoxins (SE), potentiated by bacterial lipopolysaccharide (LPS), were studied with mice. Control animals survived…”
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Identification of novel microRNA biomarkers of viral infection by Naraghi-Arani, P, Bavari, S, Gardner, S, Jaing, C, Thissen, J

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High-Affinity, Protective Antibodies to the Binding Domain of Botulinum Neurotoxin Type A by PLESS, Dorothy D, TORRES, Edna R, REINKE, Emily K, BAVARI, Sina

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Human Antibodies to Bacterial Superantigens and Their Ability To Inhibit T-Cell Activation and Lethality by LECLAIRE, Ross D, BAVARI, Sina

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Superantigen Vaccines: A Comparative Study of Genetically Attenuated Receptor-Binding Mutants of Staphylococcal Enterotoxin A by Bavari, Sina, Dyas, Beverly, Ulrich, Robert G.

“…Superantigens exert their pathologic effects by direct binding to major histocompatibility complex (MHC) class II molecules and T cell antigen receptors (TCR),…”
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Staphylococcal enterotoxin A and toxic shock syndrome toxin compete with CD4 for human major histocompatibility complex class II binding by BAVARI, S, ULRICH, R. G

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Identifying the principal protective antigenic determinants of type A botulinum neurotoxin by Bavari, S., Pless, Dorothy D., Torres, Edna R., Lebeda, Frank J., Olson, Mark A.

“…The neurotoxins from Clostridium botulinum (BoNT serotypes A-G) exert their lethal effect by preventing the release of acetylcholine at the neuromuscular…”
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Repurposing potential of 1st generation H1-specific antihistamines as anti-filovirus therapeutics by Schafer, Adam, Cheng, Han, Xiong, Rui, Soloveva, Veronica, Retterer, Cary, Mo, Feiyan, Bavari, Sina, Thatcher, Gregory, Rong, Lijun

“…Ebola and Marburg are filoviruses and biosafety level 4 pathogens responsible for causing severe hemorrhagic fevers in humans with mortality rates up to 90%…”
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Identification of Oxidative Stress and Toll-like Receptor 4 Signaling as a Key Pathway of Acute Lung Injury by Imai, Yumiko, Kuba, Keiji, Neely, G. Greg, Yaghubian-Malhami, Rubina, Perkmann, Thomas, van Loo, Geert, Ermolaeva, Maria, Veldhuizen, Ruud, Leung, Y.H. Connie, Wang, Hongliang, Liu, Haolin, Sun, Yang, Pasparakis, Manolis, Kopf, Manfred, Mech, Christin, Bavari, Sina, Peiris, J.S. Malik, Slutsky, Arthur S., Akira, Shizuo, Hultqvist, Malin, Holmdahl, Rikard, Nicholls, John, Jiang, Chengyu, Binder, Christoph J., Penninger, Josef M.

“…Multiple lung pathogens such as chemical agents, H5N1 avian flu, or SARS cause high lethality due to acute respiratory distress syndrome. Here we report that…”
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Reemergence of Monkeypox: Prevalence, Diagnostics, and Countermeasures by Weinstein, Robert A., Nalca, Aysegul, Rimoin, Anne W., Bavari, Sina, Whitehouse, Chris A.

“…Human monkeypox is a viral zoonotic disease that occurs mostly in the rain forests of central and western Africa. However, the disease recently emerged in the…”
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Lactobacilli Activate Human Dendritic Cells That Skew T Cells toward T Helper 1 Polarization by Mohamadzadeh, Mansour, Olson, Scott, Kalina, Warren V., Ruthel, Gordon, Demmin, Gretchen L., Warfield, Kelly L., Bavari, Sina, Klaenhammer, Todd R.

“…Professional antigen-presenting dendritic cells (DCs) are critical in regulating T cell immune responses at both systemic and mucosal sites. Many Lactobacillus…”
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Second generation of diazachrysenes: Protection of Ebola virus infected mice and mechanism of action by Selaković, Života, Tran, Julie P., Kota, Krishna P., Lazić, Marija, Retterer, Cary, Besch, Robert, Panchal, Rekha G., Soloveva, Veronica, Sean, Vantongreen A., Jay, Wells B., Pavić, Aleksandar, Verbić, Tatjana, Vasiljević, Branka, Kuehl, Kathleen, Duplantier, Allen J., Bavari, Sina, Mudhasani, Rajini, Šolaja, Bogdan A.

“…Ebola virus (EBOV) causes a deadly hemorrhagic fever in humans and non-human primates. There is currently no FDA-approved vaccine or medication to counter this…”
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Discovery and early development of AVI-7537 and AVI-7288 for the treatment of Ebola virus and Marburg virus infections by Iversen, Patrick L, Warren, Travis K, Wells, Jay B, Garza, Nicole L, Mourich, Dan V, Welch, Lisa S, Panchal, Rekha G, Bavari, Sina

“…There are no currently approved treatments for filovirus infections. In this study we report the discovery process which led to the development of antisense…”
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The evolving field of biodefence: therapeutic developments and diagnostics by Bavari, Sina, Burnett, James C, Henchal, Erik A, Schmaljohn, Alan L

“…The threat of bioterrorism and the potential use of biological weapons against both military and civilian populations has become a major concern for…”
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