Search Results - "Bauzo, Rayna M."

Implication of the melanocortin-3 receptor in the regulation of food intake by Irani, Boman G., Xiang, Zhimin, Yarandi, Hossein N., Holder, Jerry R., Moore, Marcus C., Bauzo, Rayna M., Proneth, Bettina, Shaw, Amanda M., Millard, William J., Chambers, James B., Benoit, Stephen C., Clegg, Deborah J., Haskell-Luevano, Carrie

“…The melanocortin system is well recognized to be involved in the regulation of food intake, body weight, and energy homeostasis. To probe the role of the MC 3…”
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Structure−Activity Relationships of the Melanocortin Tetrapeptide Ac-His-DPhe-Arg-Trp-NH2 at the Mouse Melanocortin Receptors:  Part 2 Modifications at the Phe Position by Holder, Jerry Ryan, Bauzo, Rayna M, Xiang, Zhimin, Haskell-Luevano, Carrie

“…The melanocortin pathway is an important participant in skin pigmentation, steroidogenesis, obesity, energy homeostasis and exocrine gland function. The…”
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Structure−Activity Relationships of the Melanocortin Tetrapeptide Ac-His-DPhe-Arg-Trp-NH2 at the Mouse Melanocortin Receptors. 1. Modifications at the His Position by Holder, Jerry Ryan, Bauzo, Rayna M, Xiang, Zhimin, Haskell-Luevano, Carrie

“…The melanocortin pathway is an important participant in obesity and energy homeostasis. The centrally located melanocortin-3 and melanocortin-4 receptors…”
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Structure−Activity Relationships of the Melanocortin Tetrapeptide Ac-His-d-Phe-Arg-Trp-NH2 at the Mouse Melanocortin Receptors. 4. Modifications at the Trp Position by Holder, Jerry Ryan, Xiang, Zhimin, Bauzo, Rayna M, Haskell-Luevano, Carrie

“…The melanocortin pathway is involved in the regulation of several physiological functions including skin pigmentation, steroidogenesis, obesity, energy…”
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Identification of Putative Agouti-Related Protein(87−132)-Melanocortin-4 Receptor Interactions by Homology Molecular Modeling and Validation Using Chimeric Peptide Ligands by Wilczynski, Andrzej, Wang, Xiang S, Joseph, Christine G, Xiang, Zhimin, Bauzo, Rayna M, Scott, Joseph W, Sorensen, Nicholas B, Shaw, Amanda M, Millard, William J, Richards, Nigel G, Haskell-Luevano, Carrie

“…Agouti-related protein (AGRP) is one of only two naturally known antagonists of G-protein-coupled receptors (GPCRs) identified to date. Specifically, AGRP…”
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Characterization of Melanocortin NDP-MSH Agonist Peptide Fragments at the Mouse Central and Peripheral Melanocortin Receptors by Haskell-Luevano, Carrie, Holder, Jerry Ryan, Monck, Eileen K, Bauzo, Rayna M

“…The central melanocortin receptors, melanocortin-4 (MC4R) and melanocortin-3 (MC3R), are involved in the regulation of satiety and energy homeostasis. The MC4R…”
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Design and pharmacology of peptoids and peptide-peptoid hybrids based on the melanocortin agonists core tetrapeptide sequence by HOLDER, Jerry Ryan, BAUZO, Rayna M, ZHIMIN XIANG, SCOTT, Joseph, HASKELL-LUEVANO, Carrie

“…A series of N-substituted glycine oligomers (peptoids) and peptide-peptoid hybrids were synthesized based on the Ac-His-Phe-Arg-Trp-NH(2) tetrapeptide…”
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Characterization of aliphatic, cyclic, and aromatic N-terminally capped His-D-Phe-Arg-Trp-NH2 tetrapeptides at the melanocortin receptors by HOLDER, Jerry Ryan, MARQUES, Fernanda F, ZHIMIN XIANG, BAUZO, Rayna M, HASKELL-LUEVANO, Carrie

“…The melanocortin system is implicated in multiple physiological pathways including pigmentation, inflammation, erectile function, feeding behavior, energy…”
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The cystine–glutamate transporter enhancer N-acetyl-l-cysteine attenuates cocaine-induced changes in striatal dopamine but not self-administration in squirrel monkeys by Bauzo, Rayna M., Kimmel, Heather L., Howell, Leonard L.

“…Extrasynaptic glutamate has been shown to regulate dopamine function in the mesocorticolimbic pathway, which plays an important role in the behavioral…”
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A critical role for the melanocortin 4 receptor in stress-induced relapse to nicotine seeking in rats by Qi, Xiaoli, Yamada, Hidetaka, Corrie, Lu W., Ji, Yue, Bauzo, Rayna M., Alexander, Jon C., Bruijnzeel, Adrie W.

“…Tobacco addiction is characterized by a lack of control over smoking and relapse after periods of abstinence. Smoking cessation leads to a dysphoric state that…”
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Tobacco smoke diminishes neurogenesis and promotes gliogenesis in the dentate gyrus of adolescent rats by Bruijnzeel, Adrie W, Bauzo, Rayna M, Munikoti, Vikram, Rodrick, Gene B, Yamada, Hidetaka, Fornal, Casimir A, Ormerod, Brandi K, Jacobs, Barry L

“…Abstract Brain disorders and environmental factors can affect neurogenesis and gliogenesis in the hippocampus. These studies investigated the effects of…”
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Repeated pre-exposure to tobacco smoke potentiates subsequent locomotor responses to nicotine and tobacco smoke but not amphetamine in adult rats by Bruijnzeel, Adrie W., Rodrick, Gene, Singh, Rajendra P., Derendorf, Hartmut, Bauzo, Rayna M.

“…These studies investigated if pre-exposure to tobacco smoke affects the locomotor response to tobacco smoke, nicotine, and amphetamine in adult rats. The rats…”
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Interactions between the mGluR2/3 agonist, LY379268, and cocaine on in vivo neurochemistry and behavior in squirrel monkeys by Bauzo, Rayna M., Kimmel, Heather L., Howell, Leonard L.

“…Recent evidence indicates that group II metabotropic glutamate receptors (mGluR2 and mGluR3) may play a role in the pathology of cocaine addiction. The purpose…”
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Preadolescent tobacco smoke exposure leads to acute nicotine dependence but does not affect the rewarding effects of nicotine or nicotine withdrawal in adulthood in rats by Yamada, Hidetaka, Bishnoi, Mahendra, Keijzers, Kim F.M., van Tuijl, Irma A., Small, Elysia, Shah, Hina P., Bauzo, Rayna M., Kobeissy, Firas H., Sabarinath, Sreedharan N., Derendorf, Hartmut, Bruijnzeel, Adrie W.

“…Epidemiological studies indicate that parental smoking increases the risk for smoking in children. However, the underlying mechanisms by which parental smoking…”
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Role of dopamine transporters in the behavioral effects of 3,4-methylenedioxymethamphetamine (MDMA) in nonhuman primates by Fantegrossi, William E., Bauzo, Rayna M., Manvich, Daniel M., Morales, Jose C., Votaw, John R., Goodman, Mark M., Howell, Leonard L.

“…Rationale The interoceptive and reinforcing effects of 3,4-methylenedioxymethamphetamine (MDMA) are similar to those of psychostimulants, but the role of…”
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A Solid-Phase Approach to Mouse Melanocortin Receptor Agonists Derived from a Novel Thioether Cyclized Peptidomimetic Scaffold by Bondebjerg, Jon, Xiang, Zhimin, Bauzo, Rayna M, Haskell-Luevano, Carrie, Meldal, Morten

“…The solid-phase synthesis of a novel thioether cyclized peptidomimetic scaffold, displaying functionality at the i to i + 3 positions, is reported. The…”
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Structure-activity relationships of the melanocortin tetrapeptide Ac-His-DPhe-Arg-Trp-NH2 at the mouse melanocortin receptors. Part 3: modifications at the Arg position by HOLDER, Jerry Ryan, ZHIMIN XIANG, BAUZO, Rayna M, HASKELL-LUEVANO, Carrie

“…The melanocortin pathway is involved in the regulation of several physiological functions including skin pigmentation, steroidogenesis, obesity, energy…”
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N-Terminal Fatty Acylated His-dPhe-Arg-Trp-NH2 Tetrapeptides:  Influence of Fatty Acid Chain Length on Potency and Selectivity at the Mouse Melanocortin Receptors and Human Melanocytes by Todorovic, Aleksandar, Holder, Jerry Ryan, Bauzo, Rayna M, Scott, Joseph Walker, Kavanagh, Renny, Abdel-Malek, Zalfa, Haskell-Luevano, Carrie

“…The melanocortin system is involved in the regulation of a diverse number of physiologically important pathways including pigmentation, feeding behavior,…”
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Stereochemical Studies of the Monocyclic Agouti-Related Protein (103−122) Arg-Phe-Phe Residues:  Conversion of a Melanocortin-4 Receptor Antagonist into an Agonist and Results in the Discovery of a Potent and Selective Melanocortin-1 Agonist by Joseph, Christine G, Wang, Xiang S, Scott, Joseph W, Bauzo, Rayna M, Xiang, Zhimin, Richards, Nigel G, Haskell-Luevano, Carrie

“…The agouti-related protein (AGRP) is an endogenous antagonist of the centrally expressed melanocortin receptors. The melanocortin-4 receptor (MC4R) is involved…”
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Animal models of nicotine withdrawal: intracranial self-stimulation and somatic signs of withdrawal by Bauzo, Rayna M, Bruijnzeel, Adrie W

“…Tobacco addiction is one of the leading causes of preventable death worldwide. Despite the negative health outcomes of tobacco use and a desire to quit, there…”
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