Search Results - "Baur, Wendy E."

Angiotensin II-induced TLR4 mediated abdominal aortic aneurysm in apolipoprotein E knockout mice is dependent on STAT3 by Qin, Zhexue, Bagley, Jessamyn, Sukhova, Galina, Baur, Wendy E, Park, Ho-Jin, Beasley, Debbie, Libby, Peter, Zhang, Yali, Galper, Jonas B

“…Abstract Abdominal Aortic Aneurysm (AAA) is a major cause of mortality and morbidity in men over 65 years of age. Male apolipoprotein E knockout (ApoE−/− )…”
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Rapid Estrogen Receptor Signaling Is Essential for the Protective Effects of Estrogen Against Vascular Injury by BERNELOT MOENS, Sophie J, SCHNITZLER, Gavin R, IYER, Lakshmanan K, KARAS, Richard H, NICKERSON, Moriah, HUIMING GUO, UEDA, Kazutaka, QING LU, ARONOVITZ, Mark J, NICKERSON, Heather, BAUR, Wendy E, HANSEN, Ulla

“…Clinical trial and epidemiological data support that the cardiovascular effects of estrogen are complex, including a mixture of both potentially beneficial and…”
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Striatin Assembles a Membrane Signaling Complex Necessary for Rapid, Nongenomic Activation of Endothelial NO Synthase by Estrogen Receptor α by Lu, Qing, Pallas, David C., Surks, Howard K., Baur, Wendy E., Mendelsohn, Michael E., Karas, Richard H., Housman, David E.

“…Steroid hormone receptors (SHRs) are ligand-activated transcription factors that regulate gene expression. SHRs also mediate rapid, nongenomic cellular…”
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MicroRNA-Offset RNA Alters Gene Expression and Cell Proliferation by Zhao, Jin, Schnitzler, Gavin R, Iyer, Lakshmanan K, Aronovitz, Mark J, Baur, Wendy E, Karas, Richard H

“…MicroRNA-offset RNAs (moRs) were first identified in simple chordates and subsequently in mouse and human cells by deep sequencing of short RNAs. MoRs are…”
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Mixed lineage kinase-3 prevents cardiac dysfunction and structural remodeling with pressure overload by Calamaras, Timothy D, Baumgartner, Robert A, Aronovitz, Mark J, McLaughlin, Angela L, Tam, Kelly, Richards, Daniel A, Cooper, Craig W, Li, Nathan, Baur, Wendy E, Qiao, Xiaoying, Wang, Guang-Rong, Davis, Roger J, Kapur, Navin K, Karas, Richard H, Blanton, Robert M

“…Myocardial hypertrophy is an independent risk factor for heart failure (HF), yet the mechanisms underlying pathological cardiomyocyte growth are incompletely…”
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Estrogen Receptor–Mediated Regulation of MicroRNA Inhibits Proliferation of Vascular Smooth Muscle Cells by Zhao, Jin, Imbrie, Gregory A, Baur, Wendy E, Iyer, Lakshmanan K, Aronovitz, Mark J, Kershaw, Tanya B, Haselmann, Greta M, Lu, Qing, Karas, Richard H

“…OBJECTIVE—Estradiol (E2) regulates gene transcription by activating estrogen receptor-α and estrogen receptor-β. Many of the genes regulated by E2 via estrogen…”
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Vascular mineralocorticoid receptor regulates microRNA-155 to promote vasoconstriction and rising blood pressure with aging by DuPont, Jennifer J, McCurley, Amy, Davel, Ana P, McCarthy, Joseph, Bender, Shawn B, Hong, Kwangseok, Yang, Yan, Yoo, Jeung-Ki, Aronovitz, Mark, Baur, Wendy E, Christou, Demetra D, Hill, Michael A, Jaffe, Iris Z

“…Hypertension is nearly universal yet poorly controlled in the elderly despite proven benefits of intensive treatment. Mice lacking mineralocorticoid receptors…”
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MAP kinase mediates growth factor-induced nuclear translocation of estrogen receptor α by Lu, Qing, Ebling, Heather, Mittler, Jens, Baur, Wendy E, Karas, Richard H

“…In addition to mediating the classical transcriptional effects of estrogen, estrogen receptors (ERs) are now known to regulate gene expression in the absence…”
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Regulation of estrogen receptor alpha-mediated transcription by a direct interaction with protein phosphatase 2A by Lu, Qing, Surks, Howard K, Ebling, Heather, Baur, Wendy E, Brown, Donald, Pallas, David C, Karas, Richard H

“…Estrogen receptor alpha (ERalpha) mediates the effects of estrogen by altering gene expression following hormone binding. It has recently been shown that…”
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Endothelial progenitor cells delivered into the pericardial space incorporate into areas of ischemic myocardium by Saltzman, Adam J, Choi, Sung W, Dabreo, Alexandra, Baur, Wendy E, Weiss, Eric, Nguyen, Khan, Ishibashi, Fumiyuki, Celestin, Flore F, Karia, Darshak H, Pandian, Natesa G, Karas, Richard H, Waxman, Sergio

“…Abstract Objective Our objective was to determine whether autologous endothelial progenitor cells (EPCs) delivered into the pericardial space will migrate to…”
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Sex differences in the role of the smooth muscle cell mineralocorticoid receptor in cardiovascular aging by DuPont, Jennifer J., Kim, Seung K., Sun, Zhe, Aronovitz, Mark J., Baur, Wendy E., Meininger, Gerald A., Hill, Michael A., Jaffe, Iris Z.

“…Vascular aging is a process that involves the development of vasomotor dysfunction and vessel stiffening, which leads to cardiovascular disease (CVD). Clinical…”
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Estrogen receptor-mediated regulation of microRNA inhibits proliferation of vascular smooth muscle cells: Zhao_ Estrogen regulation of microRNA in the vasculature by Zhao, Jin, Imbrie, Gregory A, Baur, Wendy E, Iyer, Lakshmanan K., Aronovitz, Mark, Kershaw, Tanya B, Haselmann, Greta M, Lu, Qing, Karas, Richard H

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A complex role for the progesterone receptor in the response to vascular injury by Karas, R H, van Eickels, M, Lydon, J P, Roddy, S, Kwoun, M, Aronovitz, M, Baur, W E, Conneely, O, O'Malley, B W, Mendelsohn, M E

“…Clinical studies of hormone replacement therapy to prevent cardiovascular diseases have heightened interest in the cardiovascular effects of progestins…”
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Growth factor activation of the estrogen receptor in vascular cells occurs via a mitogen-activated protein kinase-independent pathway by Karas, R H, Gauer, E A, Bieber, H E, Baur, W E, Mendelsohn, M E

“…The classical estrogen receptor ERalpha mediates many of the known cardiovascular effects of estrogen and is expressed in male and female vascular cells…”
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Regulation of Estrogen Receptor α-mediated Transcription by a Direct Interaction with Protein Phosphatase 2A by Qing Lu, Howard K. Surks, Heather Ebling, Wendy E. Baur, Donald Brown, David C. Pallas, Richard H. Karas

“…Estrogen receptor α (ERα) mediates the effects of estrogen by altering gene expression following hormone binding. It has recently been shown that…”
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Human vascular smooth muscle cells express an estrogen receptor isoform by Karas, Richard H., Baur, Wendy E., van Eickles, Martin, Mendelsohn, Michael E.

“…In women, estrogen (E2) exerts a clinically relevant anti-atherogenic effect. The atheroprotective effects of E2 are mediated both by E2-induced changes in…”
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Differential-display polymerase chain reaction identifies nucleophosmin as an estrogen-regulated gene in human vascular smooth muscle cells by Koike, Hideo, Karas, Richard H., Baur, Wendy E., O'Donnell, Thomas F., Mendelsohn, Michael E.

“…Purpose: Atheroprotective effects of estrogen (E 2) are well documented and are due in part to direct effects of E 2 on vascular cells. We recently…”
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