Search Results - "Baumert, Mark"

Proteomics Characterization of Extracellular Space Components in the Human Aorta by Didangelos, Athanasios, Yin, Xiaoke, Mandal, Kaushik, Baumert, Mark, Jahangiri, Marjan, Mayr, Manuel

“…The vascular extracellular matrix (ECM) is essential for the structural integrity of the vessel wall and also serves as a substrate for the binding and…”
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Localization of sterols and oxysterols in mouse brain reveals distinct spatial cholesterol metabolism by Yutuc, Eylan, Angelini, Roberto, Baumert, Mark, Mast, Natalia, Pikuleva, Irina, Newton, Jillian, Clench, Malcolm R., Skibinski, David O. F., Howell, Owain W., Wang, Yuqin, Griffiths, William J.

“…Dysregulated cholesterol metabolism is implicated in a number of neurological disorders. Many sterols, including cholesterol and its precursors and…”
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Shotgun lipidomics on a LTQ Orbitrap mass spectrometer by successive switching between acquisition polarity modes by Schuhmann, Kai, Almeida, Reinaldo, Baumert, Mark, Herzog, Ronny, Bornstein, Stefan R., Shevchenko, Andrej

“…Top–down shotgun lipidomics relies on direct infusion of total lipid extracts into a high‐resolution tandem mass spectrometer and implies that individual…”
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Integration of Ion Mobility MSE after Fully Automated, Online, High-Resolution Liquid Extraction Surface Analysis Micro-Liquid Chromatography by Lamont, Lieke, Baumert, Mark, Ogrinc Potočnik, Nina, Allen, Mark, Vreeken, Rob, Heeren, Ron M. A, Porta, Tiffany

“…Direct analysis by mass spectrometry (imaging) has become increasingly deployed in preclinical and clinical research due to its rapid and accurate readouts…”
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Comparative Lipidomics Profiling of Human Atherosclerotic Plaques by Stegemann, Christin, Drozdov, Ignat, Shalhoub, Joseph, Humphries, Julia, Ladroue, Christophe, Didangelos, Athanasios, Baumert, Mark, Allen, Mark, Davies, Alun H, Monaco, Claudia, Smith, Alberto, Xu, Qingbo, Mayr, Manuel

“…BACKGROUND—We sought to perform a systematic lipid analysis of atherosclerotic plaques using emerging mass spectrometry techniques. METHODS AND RESULTS—A…”
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Using a single, high mass resolution mass spectrometry platform to investigate ion suppression effects observed during tissue imaging by Tomlinson, Laura, Fuchser, Jens, Fütterer, Arne, Baumert, Mark, Hassall, David G., West, Andrew, Marshall, Peter S.

“…RATIONALE The signal intensity of a given molecule across a tissue section when measured using mass spectrometry imaging (MSI) is prone to changes caused by…”
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Rapid profiling of triglycerides in human breast milk using liquid extraction surface analysis Fourier transform mass spectrometry reveals new very long chain fatty acids and differences within individuals by Koulman, Albert, Furse, Samuel, Baumert, Mark, Goldberg, Gail, Bluck, Les

“…Rationale We describe a novel method for preparing milk samples and profiling their triglyceride (TG) fractions. This method was used to explore how the TG…”
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Hemoglobin Variant Analysis via Direct Surface Sampling of Dried Blood Spots Coupled with High-Resolution Mass Spectrometry by Edwards, Rebecca L, Creese, Andrew J, Baumert, Mark, Griffiths, Paul, Bunch, Josephine, Cooper, Helen J

“…Hemoglobinopathies are the most common inherited disorders. Newborn blood screening for clinically significant hemoglobin variants, including sickle (HbS),…”
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Integration of Ion Mobility MS E after Fully Automated, Online, High-Resolution Liquid Extraction Surface Analysis Micro-Liquid Chromatography by Lamont, Lieke, Baumert, Mark, Ogrinc Potočnik, Nina, Allen, Mark, Vreeken, Rob, Heeren, Ron M A, Porta, Tiffany

“…Direct analysis by mass spectrometry (imaging) has become increasingly deployed in preclinical and clinical research due to its rapid and accurate readouts…”
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Correlation of Skin Blanching and Percutaneous Absorption for Glucocorticoid Receptor Agonists by Matrix-Assisted Laser Desorption Ionization Mass Spectrometry Imaging and Liquid Extraction Surface Analysis with Nanoelectrospray Ionization Mass Spectrometry by Marshall, Peter, Toteu-Djomte, Valerie, Bareille, Philippe, Perry, Hayley, Brown, Gillian, Baumert, Mark, Biggadike, Keith

“…Matrix-assisted laser desorption/ionization-mass spectrometry imaging (MALDI-MSI) and liquid extraction surface analysis (LESA) with nanoelectrospray…”
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Application of the Exactive Plus EMR for automated protein-ligand screening by non-covalent mass spectrometry by Maple, Hannah J., Scheibner, Olaf, Baumert, Mark, Allen, Mark, Taylor, Richard J., Garlish, Rachel A., Bromirski, Maciej, Burnley, Rebecca J.

“…RATIONALE Non‐covalent mass spectrometry (MS) offers considerable potential for protein‐ligand screening in drug discovery programmes. However, there are some…”
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Simultaneous selected reaction monitoring, MS/MS and MS3 quantitation for the analysis of pharmaceutical compounds in human plasma using chip-based infusion by Leuthold, Luc Alexis, Grivet, Chantal, Allen, Mark, Baumert, Mark, Hopfgartner, Gérard

“…An assay method with mass spectrometric detection was developed for the quantitative analysis of a pharmaceutical compound and its major metabolite in human…”
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Use of a Microchip Device Coupled with Mass Spectrometry for Ligand Screening of a Multi-Protein Target by Keetch, Catherine A, Hernández, Helena, Sterling, Alistair, Baumert, Mark, Allen, Mark H, Robinson, Carol V

“…Nanoflow electrospray mass spectrometry has been applied previously to investigate noncovalent protein−protein and protein−ligand interactions. Here we…”
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Simultaneous selected reaction monitoring, MS/MS and MS 3 quantitation for the analysis of pharmaceutical compounds in human plasma using chip‐based infusion by Leuthold, Luc Alexis, Grivet, Chantal, Allen, Mark, Baumert, Mark, Hopfgartner, Gérard

“…An assay method with mass spectrometric detection was developed for the quantitative analysis of a pharmaceutical compound and its major metabolite in human…”
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