Search Results - "Baumeister, Hans"

Synthesis, storage, and release of vascular endothelial growth factor/vascular permeability factor (VEGF/VPF) by human mast cells: implications for the biological significance of VEGF206 by Grützkau, A, Krüger-Krasagakes, S, Baumeister, H, Schwarz, C, Kögel, H, Welker, P, Lippert, U, Henz, B M, Möller, A

“…Mast cells have been implicated in various diseases that are accompanied by neovascularization. The exact mechanisms by which mast cells might mediate an…”
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CetuGEX and cetuximab in recurrent/metastatic squamous cell carcinoma of the head and neck (RM-HNSCC): PK/PD results from the phase II RESGEX study by Baumeister, Hans, Zurlo, Alfredo, Fayette, Jerome, Dietrich, Bruno, Keilholz, Ulrich

“…Abstract only 61 Background: Standard treatment for RM-HNSCC is a combination of cisplatin (P), 5-FU (F), and the EGFR blocking monoclonal antibody (mAb)…”
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Safety and tolerability results of the GATTO study, a phase Ib study combining the anti-TA-MUC1 antibody gatipotuzumab with the anti-EGFR tomuzotuximab or panitumumab in patients with refractory solid tumors by Ochsenreither, Sebastian, Zurlo, Alfredo, Garralda, Elena, Matos, Ignacio, Klinghammer, Konrad Friedrich, Del Conte, Gianluca, Macchini, Marina, Rolling, Christina C, Kebenko, Maxim, Saavedra Santa Gadea, Omar, Raspagliesi, Francesco, Larusso, Domenica, ahrens-Fath, Isabelle, Habel, Beate, Baumeister, Hans, Fiedler, Walter M.

“…Abstract only 2524 Background: The phase I GATTO study explored the feasibility, tolerability and preliminary activity of combining gatipotuzumab (GAT), a…”
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Activity results of the GATTO study, a phase Ib study combining the anti-TA-MUC1 antibody gatipotuzumab with the anti-EGFR tomuzotuximab or panitumumab in patients with refractory solid tumors by Garralda, Elena, Del Conte, Gianluca, Macchini, Marina, Matos, Ignacio, Klinghammer, Konrad Friedrich, Saavedra Santa Gadea, Omar, Fiedler, Walter M., Rolling, Christina C, Kebenko, Maxim, Raspagliesi, Francesco, Larusso, Domenica, ahrens-Fath, Isabelle, Habel, Beate, Baumeister, Hans, Zurlo, Alfredo, Ochsenreither, Sebastian

“…Abstract only 2522 Background: The phase I GATTO study explored the feasibility, tolerability and preliminary activity of combining Gatipotuzumab (GAT), a…”
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Method for the immunological detection of silver-stained proteins on nitrocellulose membranes by Schärfke, M, Baumeister, H, Meyerhof, W

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Cloning, Expression, Pharmacology and Tissue Distribution of the Mouse Somatostatin Receptor Subtype 5 by Baumeister, Hans, Kreuzer, Oliver J., Roosterman, Dirk, Schäfer, Judith, Meyerhof, Wolfgang

“…The gene encoding the mouse somatostatin receptor subtype 5 has been isolated from a genomic library and the mRNA start point mapped to position −95 relative…”
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Rat insulin-degrading enzyme: cleavage pattern of the natriuretic peptide hormones ANP, BNP, and CNP revealed by HPLC and mass spectrometry by Mueller, Dieter, Schulze, Christian, Baumeister, Hans, Buck, Friedrich, Richter, Dietmar

“…The degradation of atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP), and C-type natriuretic peptide (CNP) by insulin-degrading enzyme (IDE)…”
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The GATTO study: A phase I of the anti-MUC1 Gatipotuzumab (GAT) in combination with the anti-EGFR Tomuzotuximab (TO) in patients with EGFR positive solid tumors by Ochsenreither, Sebastian, Keilholz, Ulrich, Klinghammer, Konrad Friedrich, Dicke, Christina, Kebenko, Maxim, Garralda, Elena, Tabernero, Josep, Matos, Ignacio, Lorusso, Domenica, Raspagliesi, Francesco, Gianni, Luca, Del Conte, Gianluca, Habel, Beate, Baumeister, Hans, Belli, Riccardo, Zurlo, Alfredo, Fiedler, Walter M.

“…Abstract only…”
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Glyco-optimized trastuzumab-GEX, a novel anti-HER2 monoclonal antibody with ADCC activity: A phase I clinical study in patients with HER2-positive tumors by Samonigg, Hellmut, De Dosso, Sara, Perotti, Antonella, Fiedler, Walter, Gastl, Guenther, Dietrich, Bruno, Eckert, Kelvin, Baumeister, Hans, Salzberg, Marc Oliver, Goletz, Steffen

“…Abstract only…”
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The rat insulin‐degrading enzyme by Baumeister, Hans, Müller, Dieter, Rehbein, Monika, Richter, Dietmar

“…The primary structure of the rat insulin‐degrading enzyme (IDE) was determined by cDNA analysis. Rat IDE, as well as the previously characterized homologs from…”
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Phase I study of TrasGEX, a glyco-optimised anti-HER2 monoclonal antibody, in patients with HER2-positive solid tumours by Fiedler, Walter, Stoeger, Herbert, Perotti, Antonella, Gastl, Guenther, Weidmann, Jens, Dietrich, Bruno, Baumeister, Hans, Danielczyk, Antje, Goletz, Steffen, Salzberg, Marc, De Dosso, Sara

“…PurposeTrasGEX is a second-generation monoclonal antibody of trastuzumab, glyco-optimised to enhance antibody-dependent cellular cytotoxicity while fully…”
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Phase I study of tomuzotuximab, a glycoengineered therapeutic antibody against the epidermal growth factor receptor, in patients with advanced carcinomas by Fiedler, Walter, Cresta, Sara, Schulze-Bergkamen, Henning, De Dosso, Sara, Weidmann, Jens, Tessari, Anna, Baumeister, Hans, Danielczyk, Antje, Dietrich, Bruno, Goletz, Steffen, Zurlo, Alfredo, Salzberg, Marc, Sessa, Cristiana, Gianni, Luca

“…BackgroundChanges in glycosylation of the constant domain (Fc) of monoclonal antibodies (mAbs) enhance antibody-dependent cell-mediated cytotoxicity…”
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Atrial natriuretic peptide (ANP) is a high‐affinity substrate for rat insulin‐degrading enzyme by MÜLLER, Dieter, BAUMEISTER, Hans, BUCK, Friedrich, RICHTER, Dietmar

“…A cytosolic protein specifically binding to and degrading atrial natriuretic peptide (ANP) was purified from rat brain homogenate. Based on partial amino acid…”
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First-in-human phase I study of CetuGEX, a novel anti-EGFR monoclonal antibody (mAb) with optimized glycosylation and antibody dependent cellular cytotoxicity by Fiedler, Walter, Sessa, Cristiana, Gianni, Luca, Cresta, Sara, Schulze-Bergkamen, Henning, Weidmann, Jens, De Dosso, Sara, Tessari, Anna, Salzberg, Marc Oliver, Baumeister, Hans, Danielczyk, Antje, Dietrich, Bruno, Nippgen, Johannes, Goletz, Steffen

“…Abstract only 3008 Background: Epidermal growth factor receptor (EGFR) is a validated target in cancer. EGFR antagonists in clinical use do not exploit the…”
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The POU Domain Transcription Factor Tst-1 Activates Somatostatin Receptor 1 Gene Expression in Pancreatic β-Cells by Hans Baumeister, Wolfgang Meyerhof

“…The peptide hormone somatostatin inhibits the release of insulin. The gene encoding somatostatin receptor 1 is expressed in pancreatic β-cells and insulinoma…”
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In vitro priming of tumor-specific cytotoxic T lymphocytes using allogeneic dendritic cells derived from the human MUTZ-3 cell line by SANTEGOETS, Saskia J. A. M, SCHREURS, Marco W. J, HOOIJBERG, Erik, DE GRUIJL, Tanja D, MASTERSON, Allan J, LIU, Ying Poi, GOLETZ, Steffen, BAUMEISTER, Hans, KUETER, Esther W. M, LOUGHEED, Sinéad M, VAN DEN EERTWEGH, Alfons J. M, SCHEPER, Rik J

“…The adoptive transfer of in vitro-induced and expanded tumor-specific cytotoxic T lymphocytes (CTL) presents a promising immunotherapeutic approach for the…”
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Somatostatin receptor subtype 1 modulates basal inhibition of growth hormone release in somatotrophs by Kreienkamp, Hans-Jürgen, Akgün, Ercan, Baumeister, Hans, Meyerhof, Wolfgang, Richter, Dietmar

“…Somatostatin (SST) inhibits the secretion of many peptide hormones including growth hormone (GH). The various functions of SST are mediated through at least…”
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The POU domain transcription factor Tst-1 activates somatostatin receptor 1 gene expression in pancreatic beta -cells by Baumeister, H, Meyerhof, W

“…The peptide hormone somatostatin inhibits the release of insulin. The gene encoding somatostatin receptor 1 is expressed in pancreatic beta-cells and…”
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Dual Regulation Of Somatostatin Receptor Subtype 1 Gene Expression By Pit-1 In Anterior Pituitary GH3 Cells by Baumeister, Hans, Wegner, Michael, Richter, Dietmar, Meyerhof, Wolfgang

“…Somatostatin represents a major release inhibiting factor for hypophyseal hormones and mediates its action via five receptor subtypes, sst1–sst5, that are all…”
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Gene regulation of somatostatin receptors in rats by Baumeister, Hans, Meyerhof, Wolfgang

“…Using the rat as a model, the present article summarises the spatial, temporal and hormonal regulation of the somatostatin receptor subtypes and their mRNAs in…”
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