Search Results - "Baumann, Florian M."
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Early CD8 T-cell memory precursors and terminal effectors exhibit equipotent in vivo degranulation
Published in Cellular & molecular immunology (01-07-2015)“…Early after priming, effector CD8 T cells are distinguished into memory precursor and short-lived effector cell subsets (MPECs and SLECs). Here, we delineated…”
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Dicer Regulates the Balance of Short-Lived Effector and Long-Lived Memory CD8 T Cell Lineages
Published in PloS one (14-09-2016)“…MicroRNAs constitute a major post-transcriptional mechanism for controlling protein expression, and are emerging as key regulators during T cell development…”
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Programming of CD8 T Cell Quantity and Polyfunctionality by Direct IL-1 Signals
Published in The Journal of immunology (1950) (15-12-2018)“…IL-1, generally considered an amplifier of adaptive immune responses, has been proposed for use as adjuvant during immunization with weak immunogens. However,…”
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Vitamin D receptor signals regulate effector and memory CD8 T cell responses to infections in mice
Published in The Journal of nutrition (01-12-2014)“…Vitamin D insufficiency is associated with broad-ranging human disease sequelae such as bone disease, cancer, cardiovascular disease, allergy, autoimmune…”
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PD-1 signals instruct a critical metabolic switch for maintenance of T cell memory
Published in The Journal of immunology (1950) (01-05-2017)“…PD-1 is highly expressed on CD8 T cells during activation, both in acute and chronic viral infections. Inhibitory signaling in cytotoxic T cells through the…”
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