Search Results - "Baumann, Daniel C."
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1
Placental mTOR complex 1 regulates fetal programming of obesity and insulin resistance in mice
Published in JCI insight (08-07-2021)“…Fetal growth restriction, or low birth weight, is a strong determinant for eventual obesity and type 2 diabetes. Clinical studies suggest placental mechanistic…”
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Journal Article -
2
Serine racemase is expressed in islets and contributes to the regulation of glucose homeostasis
Published in Islets (01-11-2016)“…NMDA receptors (NMDARs) have recently been discovered as functional regulators of pancreatic β-cell insulin secretion. While these excitatory receptor channels…”
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Journal Article -
3
Afferent renal denervation attenuates DOCA‐salt hypertension in the mouse: Potential role of an IL‐1β afferent renal nerve interaction
Published in The FASEB journal (01-05-2022)“…Catheter based renal denervation (RDN) has emerged as a novel treatment for hypertension in patients. However, the mechanisms by which RDN lowers arterial…”
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Journal Article -
4
TRPV1+ Sensory Fibers in the Mouse Renal Cortex ‐ Juxtaglomerular Anatomy and Optogenetic Stimulation
Published in The FASEB journal (01-05-2022)“…Hypertension is the leading contributor to cardiovascular‐related deaths worldwide. To overcome obstacles presented by traditional drug‐based therapies for…”
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Journal Article -
5
Targeted afferent renal denervation reduces arterial pressure but not renal inflammation in established DOCA-salt hypertension in the rat
Published in American journal of physiology. Regulatory, integrative and comparative physiology (01-06-2018)“…Recent preclinical studies show renal denervation (RDNx) may be an effective treatment for hypertension; however, the mechanism remains unknown. We have…”
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Journal Article -
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SPARC: Renal Denervation Attenuates DOCA‐salt Hypertension in the Mouse
Published in The FASEB journal (01-04-2020)“…Abstract only Hypertension affects approximately one third of the adult population in the United States. Catheter based renal denervation (RDN) has emerged as…”
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Journal Article -
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Abstract 032: Afferent Renal Denervation And IL-1 Receptor Blockade Attenuate The Pathogenesis Of Hypertension In DOCA-salt Mice Similarly: Evidence For A Common Mechanism?
Published in Hypertension (Dallas, Tex. 1979) (01-09-2022)“…Abstract only Emerging evidence suggests an interaction between renal inflammation and afferent renal nerves in some preclinical models of hypertension. In…”
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Journal Article -
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Interaction of Afferent Renal Nerve Activity and IL-1R Signaling in Hypertension
Published 01-01-2024“…Renal denervation was recently approved by the FDA for the treatment of hypertension, but the mechanism by which it reduces blood pressure is unclear. Studies…”
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Dissertation