Search Results - "Baum, Marc M."

Acute antagonism in three-drug combinations for vaginal HIV prevention in humanized mice by Gallay, Philippe A., Ramirez, Christina M., Baum, Marc M.

“…Adolescent girls and young women in low- to middle-income countries are disproportionately at risk of becoming HIV-1 infected. New non-vaccine biomedical…”
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Artificial photosynthesis: semiconductor photocatalytic fixation of CO2 to afford higher organic compounds by Hoffmann, Michael R, Moss, John A, Baum, Marc M

“…Carbon dioxide is an appealing renewable feedstock for industrial chemical processes. This does not mean, however, that all chemical processes using CO(2) are…”
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Parenteral platforms for tunable, long-acting administration of a highly hydrophobic antiretroviral drug by Akhavein, Nima, Baum, Marc M., Gunawardana, Manjula, Moss, John A., Calvez, Sandrine, Remedios-Chan, Mariana, Fanter, Rob, Lenhard, Steve, Rusk, Samantha, Azzarano, Leonard, McCoy, Deborah, Jucker, Beat, Johns, Brian, Burke, Matt, Velthuisen, Emile

“…GSK2838232 (GSK8232) is a second-generation maturation inhibitor (MI) developed for the treatment of HIV with excellent broad-spectrum virological profiles…”
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The combination of the NS5A and cyclophilin inhibitors results in an additive anti-HCV inhibition in humanized mice without development of resistance by Bobardt, Michael, Ramirez, Christina M, Baum, Marc M, Ure, Daren, Foster, Robert, Gallay, Philippe A

“…We and others previously reported that the direct-acting agents (DAA) NS5A inhibitors (NS5Ai) and the host-targeting agents cyclophilin inhibitors (CypIs)…”
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CAPRISA 018: a phase I/II clinical trial study protocol to assess the safety, acceptability, tolerability and pharmacokinetics of a sustained-release tenofovir alafenamide subdermal implant for HIV prevention in women by Gengiah, Tanuja Narayansamy, Abdool Karim, Quarraisha, Harkoo, Ishana, Mansoor, Leila, Zuma, Nonhlanhla Yende, Radebe, Precious, Samsunder, Natasha, Baxter, Cheryl, Maharaj, B, Baum, Marc M, Moss, John A, Pozzetto, Bruno, Hankins, Catherine, Abdool Karim, Salim

“…IntroductionYoung African women bear a disproportionately high risk for HIV acquisition. HIV technologies that empower women to protect themselves are needed…”
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Novel multipurpose pod-intravaginal ring for the prevention of HIV, HSV, and unintended pregnancy: Pharmacokinetic evaluation in a macaque model by Smith, James M, Moss, John A, Srinivasan, Priya, Butkyavichene, Irina, Gunawardana, Manjula, Fanter, Rob, Miller, Christine S, Sanchez, Debbie, Yang, Flora, Ellis, Shanon, Zhang, Jining, Marzinke, Mark A, Hendrix, Craig W, Kapoor, Amita, Baum, Marc M

“…Globally, women bear an uneven burden for sexual HIV acquisition. Results from two clinical trials evaluating intravaginal rings (IVRs) delivering the…”
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Beta- lactam antibiotics stimulate biofilm formation in non-typeable haemophilus influenzae by up-regulating carbohydrate metabolism by Wu, Siva, Li, Xiaojin, Gunawardana, Manjula, Maguire, Kathleen, Guerrero-Given, Debbie, Schaudinn, Christoph, Wang, Charles, Baum, Marc M, Webster, Paul

“…Non-typeable Haemophilus influenzae (NTHi) is a common acute otitis media pathogen, with an incidence that is increased by previous antibiotic treatment. NTHi…”
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Fundamental aspects of long-acting tenofovir alafenamide delivery from subdermal implants for HIV prophylaxis by Gunawardana, Manjula, Remedios-Chan, Mariana, Sanchez, Debbie, Webster, Simon, Castonguay, Amalia E., Webster, Paul, Buser, Christopher, Moss, John A., Trinh, MyMy, Beliveau, Martin, Hendrix, Craig W., Marzinke, Mark A., Tuck, Michael, Caprioli, Richard M., Reyzer, Michelle L., Kuo, Joseph, Gallay, Philippe A., Baum, Marc M.

“…Global efforts aimed at preventing human immunodeficiency virus type one (HIV-1) infection in vulnerable populations appear to be stalling, limiting our…”
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Prevention of vaginal and rectal HIV transmission by antiretroviral combinations in humanized mice by Gallay, Philippe A, Chatterji, Udayan, Kirchhoff, Aaron, Gandarilla, Angel, Gunawardana, Manjula, Pyles, Richard B, Marzinke, Mark A, Moss, John A, Baum, Marc M

“…With more than 7,000 new HIV infections daily worldwide, there is an urgent need for non-vaccine biomedical prevention (nBP) strategies that are safe,…”
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Phase I trial of pod-intravaginal rings delivering antiretroviral agents for HIV-1 prevention: Rectal drug exposure from vaginal dosing with tenofovir disoproxil fumarate, emtricitabine, and maraviroc by Vincent, Kathleen Listiak, Moss, John A, Marzinke, Mark A, Hendrix, Craig W, Anton, Peter A, Gunawardana, Manjula, Dawson, Lauren N, Olive, Trevelyn J, Pyles, Richard B, Baum, Marc M

“…Intravaginal rings (IVRs) can deliver antiretroviral (ARV) agents for HIV pre-exposure prophylaxis (PrEP), theoretically overcoming adherence concerns…”
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Simultaneous Delivery of Tenofovir and Acyclovir via an Intravaginal Ring by MOSS, John A, MALONE, Amanda M, FRIEND, David R, CLARK, Meredith R, BAUM, Marc M, SMITH, Thomas J, KENNEDY, Sean, KOPIN, Etana, NGUYEN, Cali, GILMAN, Josh, BUTKYAVICHENE, Irina, VINCENT, Kathleen L, MOTAMEDI, Massoud

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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User evaluations offer promise for pod-intravaginal ring as a drug delivery platform: A mixed methods study of acceptability and use experiences by Guthrie, Kate M, Rosen, Rochelle K, Vargas, Sara E, Getz, Melissa L, Dawson, Lauren, Guillen, Melissa, Ramirez, Jaime J, Baum, Marc M, Vincent, Kathleen L

“…Effective HIV prevention requires efficient delivery of safe and efficacious drugs and optimization of user adherence. The user's experiences with the drug,…”
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Pharmacokinetics of a Multipurpose Pod-Intravaginal Ring Simultaneously Delivering Five Drugs in an Ovine Model by MOSS, John A, MALONE, Amanda M, SMITH, Thomas J, KENNEDY, Sean, NGUYEN, Cali, VINCENT, Kathleen L, MOTAMEDI, Massoud, BAUM, Marc M

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Multispecies Evaluation of a Long-Acting Tenofovir Alafenamide Subdermal Implant for HIV Prophylaxis by Gunawardana, Manjula, Remedios-Chan, Mariana, Sanchez, Debbie, Webster, Simon, Galvan, Patricia, Fanter, Rob, Castonguay, Amalia E, Webster, Paul, Moss, John A, Kuo, Joseph, Gallay, Philippe A, Vincent, Kathleen L, Motamedi, Massoud, Weinberger, Dana, Marzinke, Mark A, Hendrix, Craig W, Baum, Marc M

“…New HIV-1 infection rates far outpace the targets set by global health organizations, despite important progress in curbing the progression of the epidemic…”
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Cultivated vaginal microbiomes alter HIV-1 infection and antiretroviral efficacy in colonized epithelial multilayer cultures by Pyles, Richard B, Vincent, Kathleen L, Baum, Marc M, Elsom, Barry, Miller, Aaron L, Maxwell, Carrie, Eaves-Pyles, Tonyia D, Li, Guangyu, Popov, Vsevolod L, Nusbaum, Rebecca J, Ferguson, Monique R

“…There is a pressing need for modeling of the symbiotic and at times dysbiotic relationship established between bacterial microbiomes and human mucosal…”
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Topical Delivery of Tenofovir Disoproxil Fumarate and Emtricitabine from Pod-Intravaginal Rings Protects Macaques from Multiple SHIV Exposures by Srinivasan, Priya, Moss, John A, Gunawardana, Manjula, Churchman, Scott A, Yang, Flora, Dinh, Chuong T, Mitchell, James M, Zhang, Jining, Fanter, Rob, Miller, Christine S, Butkyavichene, Irina, McNicholl, Janet M, Smith, Thomas J, Baum, Marc M, Smith, James M

“…Topical preexposure prophylaxis (PrEP) against HIV has been marginally successful in recent clinical trials with low adherence rates being a primary factor for…”
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An intravaginal ring for real-time evaluation of adherence to therapy by Moss, John A, Baum, Marc M, Easley, Jeremiah T, Cox, Darren M, Smith, Thomas J

“…Two recent Phase III clinical trials to investigate an intravaginal ring for preventing HIV infection demonstrated that adherence to prescribed device use was…”
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Clinical SARS-CoV-2 Kinetic Profiles Are Dependent on the Viral Strain and Host Vaccination Status by Gunawardana, Manjula, Cortez, Jr, John M, Breslin, Jessica, Webster, Simon, Rochman, Nash D, Anton, Peter A, Baum, Marc M

“…The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection kinetics in a real-world, clinical setting represent a knowledge gap in…”
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Determination of phosphate/arsenate by a modified molybdenum blue method and reduction of arsenate by S2O42 by TSANG, Susanna, PHU, Frank, BAUM, Marc M, POSKREBYSHEV, Gregory A

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Characterization of structures in biofilms formed by a Pseudomonas fluorescens isolated from soil by Baum, Marc M, Kainović, Aleksandra, O'Keeffe, Teresa, Pandita, Ragini, McDonald, Kent, Wu, Siva, Webster, Paul

“…Microbial biofilms represent an incompletely understood, but fundamental mode of bacterial growth. These sessile communities typically consist of stratified,…”
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