Search Results - "Baum, L G"
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Ah, sweet mystery of death! Galectins and control of cell fate
Published in Glycobiology (Oxford) (01-10-2002)“…Control of cell death is critical in eukaryotic development, immune system homeostasis, and control of tumorigenesis. The galectin family of lectins is…”
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Multivalent Protein−Carbohydrate Interactions. A New Paradigm for Supermolecular Assembly and Signal Transduction
Published in Biochemistry (Easton) (13-03-2001)“…Many biological recognition processes involve the binding and clustering of ligand−receptor complexes and concomitant signal transduction events. Such…”
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Galectin-1 induces nuclear translocation of endonuclease G in caspase- and cytochrome c-independent T cell death
Published in Cell death and differentiation (01-12-2004)“…Galectin-1, a mammalian lectin expressed in many tissues, induces death of diverse cell types, including lymphocytes and tumor cells. The galectin-1 T cell…”
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Galectins : versatile modulators of cell adhesion, cell proliferation, and cell death
Published in Journal of molecular medicine (Berlin, Germany) (01-05-1998)“…Lectins, or carbohydrate binding proteins, recognize specific oligosaccharide structures on glycoproteins and glycolipids. Several families of animal lectins…”
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Conference Proceeding Journal Article -
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Apoptosis of T cells mediated by galectin-1
Published in Nature (London) (14-12-1995)“…Galectin-1, a member of the family of beta-galactoside binding proteins, has growth regulatory and immunomodulatory activities. We report here that galectin-1,…”
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CD45 Modulates Galectin-1-Induced T Cell Death: Regulation by Expression of Core 2 O-Glycans
Published in The Journal of immunology (1950) (15-11-2001)“…Galectin-1 induces death of immature thymocytes and activated T cells. Galectin-1 binds to T cell-surface glycoproteins CD45, CD43, and CD7, although the…”
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Journal Article -
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Human homologs of the Xenopus oocyte cortical granule lectin XL35
Published in Glycobiology (Oxford) (01-01-2001)“…The cDNAs encoding two human homologs of the Xenopus oocyte lectin, XL35, were isolated from a small intestine cDNA library and termed HL-1 and HL-2. The…”
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Journal Article -
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Galectin multimerization and lattice formation are regulated by linker region structure
Published in Glycobiology (Oxford) (01-01-2011)“…Galectins regulate cellular functions by binding to glycan ligands on cell surface glycoprotein receptors. Prototype galectins, such as galectin-1, are one…”
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CD45 Glycosylation controls T-cell life and death
Published in Immunology and cell biology (01-10-2008)“…CD45, an abundant and highly glycosylated cell‐surface protein, is a critical regulator of T‐cell development. CD45 is differentially glycosylated throughout…”
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A novel mammalian protein, p55CDC, present in dividing cells is associated with protein kinase activity and has homology to the Saccharomyces cerevisiae cell division cycle proteins Cdc20 and Cdc4
Published in Molecular and Cellular Biology (01-05-1994)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Influenza virus strains selectively recognize sialyloligosaccharides on human respiratory epithelium; the role of the host cell in selection of hemagglutinin receptor specificity
Published in Virus research (01-08-1993)“…The complement of sialyloligosaccharides present on the surface of human tracheal epithelium has been implicated as an important factor in the selection of…”
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Developing a Taste for Sweets
Published in Immunity (2002)“…Lymphocytes are covered with sugars. Some of the oligosaccharides on lymphocytes may be recognized by specific lectins such as the selectins, but what other…”
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Book Review Journal Article -
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Presentation of Galectin-1 by Extracellular Matrix Triggers T Cell Death
Published in The Journal of biological chemistry (06-02-2004)“…Apoptotic elimination of T cells at sites of inflammation or infiltration into tumors limits an effective immune response. T cell apoptosis can be initiated by…”
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Galectins and their ligands: amplifiers, silencers or tuners of the inflammatory response?
Published in Trends in Immunology (01-06-2002)“…Recent evidence has implicated galectins and their ligands as master regulators of immune cell homeostasis. Whereas some members of this family, such as…”
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Book Review Journal Article -
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The ST6Gal I sialyltransferase selectively modifies N-glycans on CD45 to negatively regulate galectin-1-induced CD45 clustering, phosphatase modulation, and T cell death
Published in The Journal of biological chemistry (28-02-2003)“…The addition of sialic acid to T cell surface glycoproteins influences essential T cell functions such as selection in the thymus and homing in the peripheral…”
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Regulation of alpha 2,3-sialyltransferase expression correlates with conversion of peanut agglutinin (PNA)+ to PNA- phenotype in developing thymocytes
Published in The Journal of biological chemistry (25-02-1993)“…Staining of thymus tissue with the plant lectin peanut agglutinin (PNA) is a classic technique for defining the cortical (PNA+) and medullary (PNA-) regions of…”
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The occurrence, recrudescence, and worsening of asthma in a population of young adults: impact of varying types of occupation
Published in Chest (01-09-1999)“…To describe the rates of exacerbation of existing asthma and incidence of new disease in Israeli men during military service. All 17-year-old Israeli nationals…”
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Molecular Basis for the Generation in Pigs of Influenza A Viruses with Pandemic Potential
Published in Journal of Virology (01-09-1998)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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