Search Results - "Baulieu, E.E."
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The Prevention of Post-Partum Relapses with Progestin and Estradiol in Multiple Sclerosis (POPART'MUS) trial: Rationale, objectives and state of advancement
Published in Journal of the neurological sciences (15-11-2009)“…Abstract Multiple sclerosis (MS) affects 1 in 1000 people in western countries, mainly women in their childbearing years. It is an autoimmune disease of the…”
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3β-Methoxypregnenolone, a pregnenolone analogue, enhances neurite outgrowth and neuronal plasticity in neuronal culture
Published in European neuropsychopharmacology (01-03-2017)Get full text
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P.2.b.026 Psychosocial stress affects core body temperature in tree shrews: a new statistical model
Published in European neuropsychopharmacology (2011)Get full text
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Steroid hormone receptors and steroid action in rat glial cells of the central and peripheral nervous system
Published in Journal of steroid biochemistry and molecular biology (01-04-1998)“…The nervous system is a target for sex steroid hormones which have profound actions on the growth, maturation, differentiation and functioning of brain cells…”
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Biosynthesis and assay of neurosteroids in rats and mice: Functional correlates
Published in Journal of steroid biochemistry and molecular biology (01-06-1995)“…Pregnenolone (PREG), synthesized de novo in rodent brain, is the precursor of PREG sulfate (S) and progesterone (PROG). PROG is further converted to…”
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The common 90‐kd protein component of non‐transformed ‘8S’ steroid receptors is a heat‐shock protein
Published in The EMBO journal (01-12-1985)“…Non‐transformed steroid receptors have an approximately 8S sedimentation coefficient that corresponds to an oligomeric structure of 250‐300 kd which includes a…”
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Overexpression of p59-HBI (FKBP59), full length and domains, and characterization of PPlase activity
Published in Biochemical and biophysical research communications (15-10-1993)“…It has been previously proposed that the rabbit p59-HBI (Heat shock protein Binding Immunophilin) or rFKBP59 (FK506 Binding Protein), found associated with the…”
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P.1.023 - 3β-Methoxypregnenolone, a pregnenolone analogue, enhances neurite outgrowth and neuronal plasticity in neuronal culture
Published in European neuropsychopharmacology (01-03-2017)Get full text
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Neurosteroids: biosynthesis, metabolism and function of pregnenolone and dehydroepiandrosterone in the brain
Published in The Journal of steroid biochemistry and molecular biology (1991)“…Pregnenolone (P) and dehydroepiandrosterone (D) accumulate in the brain as unconjugated steroids and their sulfate (S) and fatty acid (L) esters. The…”
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NEUROSTEROIDS: A NOVEL FUNCTION OF THE BRAIN
Published in Psychoneuroendocrinology (01-11-1998)“…Neurosteroids are synthetized in the central and peripheral nervous system, particularly but not exclusively in myelinating glial cells, from cholesterol or…”
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Isomerization and Oligomerization of Truncated and Mutated Tau Forms by FKBP52 are Independent Processes
Published in Journal of molecular biology (27-03-2016)“…The aggregation of the neuronal Tau protein is one molecular hallmark of Alzheimer's disease and other related tauopathies, but the precise molecular…”
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Neuraxial analgesia is not associated with an increased risk of post-partum relapses in MS
Published in Multiple sclerosis (01-04-2019)“…Background: Obstetrical analgesia remains a matter of controversy because of the fear of neurotoxicity of local anesthetics on demyelinated fibers or their…”
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Progesterone increases oligodendroglial cell proliferation in rat cerebellar slice cultures
Published in Neuroscience (2005)“…We have previously demonstrated that progesterone significantly increases the rate of myelination in organotypic slice cultures of 7-day-old rat and mouse…”
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Progesterone as a neurosteroid: synthesis and actions in rat glial cellsProceedings of Xth International Congress on Hormonal Steroids, Quebec, Canada, 17–21 June 1998
Published in The Journal of steroid biochemistry and molecular biology (01-04-1999)“…The central nervous system (CNS) and the peripheral nervous system (PNS) are targets for steroid hormones where they regulate important neuronal functions…”
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Neurosteroids: beginning of the story
Published in International review of neurobiology (2001)“…Neurosteroids are synthetisized in the central and the peripheral nervous system, in glial cells, and also in neurons, from cholesterol or steroidal precursors…”
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