Search Results - "Baulcombe, David C."

Transposon age and non-CG methylation by Wang, Zhengming, Baulcombe, David C.

“…Silencing of transposable elements (TEs) is established by small RNA-directed DNA methylation (RdDM). Maintenance of silencing is then based on a combination…”
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DNA Methylation Signatures of the Plant Chromomethyltransferases by Gouil, Quentin, Baulcombe, David C

“…DNA methylation in plants is traditionally partitioned into CG, CHG and CHH contexts (with H any nucleotide but G). By investigating DNA methylation patterns…”
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Small RNAs and heritable epigenetic variation in plants by Bond, Donna M, Baulcombe, David C

“…Highlights • sRNAs play a key role in the maintenance of DNA methylation from parent to progeny. • sRNA-mediated mechanisms have the ability to unlock the…”
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Epigenetic transitions leading to heritable, RNA-mediated de novo silencing in Arabidopsis thaliana by Bond, Donna M, Baulcombe, David C

“…In plants, RNA-directed DNA methylation (RdDM), a mechanism where epigenetic modifiers are guided to target loci by small RNAs, plays a major role in silencing…”
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Intercellular and systemic movement of RNA silencing signals by Melnyk, Charles W, Molnar, Attila, Baulcombe, David C

“…In most eukaryotes, double‐stranded RNA is processed into small RNAs that are potent regulators of gene expression. This gene silencing process is known as RNA…”
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Mobile 24 nt Small RNAs Direct Transcriptional Gene Silencing in the Root Meristems of Arabidopsis thaliana by Melnyk, Charles W., Molnar, Attila, Bassett, Andrew, Baulcombe, David C.

“…RNA silencing in flowering plants generates a signal that moves between cells and through the phloem [1, 2]. Nucleotide sequence specificity of the signal is…”
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Small Silencing RNAs in Plants Are Mobile and Direct Epigenetic Modification in Recipient Cells by Molnar, Attila, Melnyk, Charles W, Bassett, Andrew, Hardcastle, Thomas J, Dunn, Ruth, Baulcombe, David C

“…A silencing signal in plants with an RNA specificity determinant moves through plasmodesmata and the phloem. To identify the mobile RNA, we grafted Arabidopsis…”
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Enhanced resistance to bacterial and oomycete pathogens by short tandem target mimic RNAs in tomato by Canto-Pastor, Alex, Santos, Bruno A. M. C., Valli, Adrian A., Summers, William, Schornack, Sebastian, Baulcombe, David C.

“…Nucleotide binding site leucine-rich repeat (NLR) proteins of the plant innate immune system are negatively regulated by the miR482/2118 family miRNAs that are…”
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Mobile small RNAs regulate genome-wide DNA methylation by Lewsey, Mathew G., Hardcastle, Thomas J., Melnyk, Charles W., Molnar, Attila, Valli, Adrián, Urich, Mark A., Nery, Joseph R., Baulcombe, David C., Ecker, Joseph R.

“…RNA silencing at the transcriptional and posttranscriptional levels regulates endogenous gene expression, controls invading transposable elements (TEs), and…”
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Interspecific hybridization in tomato influences endogenous viral sRNAs and alters gene expression by Lopez-Gomollon, Sara, Müller, Sebastian Y, Baulcombe, David C

“…Hybridization is associated with the activation of transposable elements and changes in the patterns of gene expression leading to phenotypic changes. However,…”
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A novel DCL2-dependent miRNA pathway in tomato affects susceptibility to RNA viruses by Wang, Zhengming, Hardcastle, Thomas J, Canto Pastor, Alex, Yip, Wing Hin, Tang, Shuoya, Baulcombe, David C

“…Tomato Dicer-like2 (slDCL2) is a key component of resistance pathways against potato virus X (PVX) and tobacco mosaic virus (TMV). It is also required for…”
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Paramutation-like features of multiple natural epialleles in tomato by Gouil, Quentin, Baulcombe, David C

“…Freakish and rare or the tip of the iceberg? Both phrases have been used to refer to paramutation, an epigenetic drive that contravenes Mendel's first law of…”
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Identification and characterization of small RNAs from the phloem of Brassica napus by Buhtz, Anja, Springer, Franziska, Chappell, Louise, Baulcombe, David C, Kehr, Julia

“…Systemic signalling is indispensable for the coordination of diverse physiological processes during development, defence and nutrient allocation. Indirect…”
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22-nucleotide RNAs trigger secondary siRNA biogenesis in plants by Chen, Ho-Ming, Chen, Li-Teh, Patel, Kanu, Li, Yi-Hang, Baulcombe, David C., Wu, Shu-Hsing, Weigel, Detlef

“…The effect of RNA silencing in plants can be amplified if the production of secondary small interfering RNAs (siRNAs) is triggered by the interaction of…”
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Maternal siRNAs as regulators of parental genome imbalance and gene expression in endosperm of Arabidopsis seeds by Lu, Jie, Zhang, Changqing, Baulcombe, David C, Chen, Z. Jeffrey

“…Seed size is important to crop domestication and natural selection and is affected by the balance of maternal and paternal genomes in endosperm. Endosperm,…”
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Stepwise artificial evolution of a plant disease resistance gene by Harris, C. Jake, Slootweg, Erik J., Goverse, Aska, Baulcombe, David C.

“…Genes encoding plant nucleotide-binding leucine-rich repeat (NB-LRR) proteins confer dominant resistance to diverse pathogens. The wild-type potato NB-LRR…”
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PolIVb influences RNA-directed DNA methylation independently of its role in siRNA biogenesis by Mosher, Rebecca A, Schwach, Frank, Studholme, David, Baulcombe, David C

“…DNA-dependent RNA polymerase (Pol)IV in Arabidopsis exists in two isoforms (PolIVa and PolIVb), with NRPD1a and NRPD1b as their respective largest subunits…”
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The use of duplex-specific nuclease in ribosome profiling and a user-friendly software package for Ribo-seq data analysis by Chung, Betty Y, Hardcastle, Thomas J, Jones, Joshua D, Irigoyen, Nerea, Firth, Andrew E, Baulcombe, David C, Brierley, Ian

“…Ribosome profiling is a technique that permits genome-wide, quantitative analysis of translation and has found broad application in recent years. Here we…”
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The Polerovirus Silencing Suppressor P0 Targets ARGONAUTE Proteins for Degradation by Baumberger, Nicolas, Tsai, Ching-Hsui, Lie, Miranda, Havecker, Ericka, Baulcombe, David C.

“…Plant and animal viruses encode suppressor proteins of an adaptive immunity mechanism [1] in which viral double-stranded RNA is processed into 21–25 nt short…”
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Extraordinary transgressive phenotypes of hybrid tomato are influenced by epigenetics and small silencing RNAs by Shivaprasad, Padubidri V, Dunn, Ruth M, Santos, Bruno ACM, Bassett, Andrew, Baulcombe, David C

“…Hybrid organisms may fail to develop, be sterile or they may be more vigorous than either of the parents. Examples of hybrid vigour or hybrid necrosis in the…”
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