Search Results - "Bauer, Rudolf"
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1
A tribute to Prof. em. Dr. Dr. h.c. mult. Hildebert Wagner
Published in Pharmaceutical biology (01-12-2022)Get full text
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2
Challenges at the Time of COVID-19: Opportunities and Innovations in Antivirals from Nature
Published in Planta medica (01-07-2020)“…As viral infections are an increasing threat to human societies, the need for new therapeutic strategies is becoming even more obvious. As no vaccine is…”
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3
Discovery and resupply of pharmacologically active plant-derived natural products: A review
Published in Biotechnology advances (01-12-2015)“…Medicinal plants have historically proven their value as a source of molecules with therapeutic potential, and nowadays still represent an important pool for…”
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Natural product agonists of peroxisome proliferator-activated receptor gamma (PPARγ): a review
Published in Biochemical pharmacology (01-11-2014)“…Agonists of the nuclear receptor PPARγ are therapeutically used to combat hyperglycaemia associated with the metabolic syndrome and type 2 diabetes. In spite…”
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Antiviral activity of plant juices and green tea against SARS‐CoV‐2 and influenza virus
Published in Phytotherapy research (01-05-2022)“…Respiratory viruses pose a significant threat to global health. They initially infect the naso‐ and oropharyngeal regions, where they amplify, cause symptoms,…”
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The microbiome of medicinal plants: diversity and importance for plant growth, quality and health
Published in Frontiers in microbiology (20-12-2013)“…Past medicinal plant research primarily focused on bioactive phytochemicals, however, the focus is currently shifting due to the recognition that a significant…”
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Characterization of potentially health-promoting constituents in sea fennel (Crithmum maritimum) cultivated in the Conero Natural Park (Marche region, Central Italy)
Published in Pharmaceutical biology (01-12-2023)“…Sea fennel (Crithmum maritimum L. [Apiaceae]) is an aromatic herb rich in bioactive molecules, such as polyphenols, with potential positive effects on human…”
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Synthesis and Pharmacological In Vitro Investigations of Novel Shikonin Derivatives with a Special Focus on Cyclopropane Bearing Derivatives
Published in International journal of molecular sciences (09-03-2021)“…Melanoma is the deadliest form of skin cancer and accounts for about three quarters of all skin cancer deaths. Especially at an advanced stage, its treatment…”
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Shikonin derivatives cause apoptosis and cell cycle arrest in human chondrosarcoma cells via death receptors and MAPK regulation
Published in BMC cancer (12-07-2022)“…Abstract Background Although chondrosarcoma is the second most common primary malignant bone tumor, treatment options are limited due to its extensive…”
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Shikonin Derivatives Inhibit Inflammation Processes and Modulate MAPK Signaling in Human Healthy and Osteoarthritis Chondrocytes
Published in International journal of molecular sciences (21-03-2022)“…Osteoarthritis (OA) is the most common joint disorder and is characterized by the degeneration of articular cartilage. To develop new therapeutic approaches,…”
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HPLC-UV/HRMS methods for the unambiguous detection of adulterations of Ginkgo biloba leaves with Sophora japonica fruits on an extract level
Published in Pharmaceutical biology (01-01-2021)“…Ginkgo biloba L. (Ginkgoaceae) leaf extract is one of the most frequently sold herbal extracts. There have been reports on poor quality and adulteration of…”
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SK119, a Novel Shikonin Derivative, Leads to Apoptosis in Melanoma Cell Lines and Exhibits Synergistic Effects with Vemurafenib and Cobimetinib
Published in International journal of molecular sciences (19-05-2022)“…Melanoma is a complex and heterogenous disease, displays the deadliest form of skin cancer, and accounts for approx. 80% of all skin cancer deaths. In this…”
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13
Medicinal Plants and Their Impact on the Gut Microbiome in Mental Health: A Systematic Review
Published in Nutrients (18-05-2022)“…Various neurocognitive and mental health-related conditions have been associated with the gut microbiome, implicating a microbiome-gut-brain axis (MGBA). The…”
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Formation of 5-Aminomethyl-2,3-dihydropyridine-4(1H)-ones from 4-Amino-tetrahydropyridinylidene Salts
Published in Molecules (Basel, Switzerland) (29-09-2023)“…Various 4-aminotetrahydropyridinylidene salts were treated with aldehydes in an alkaline medium. Their conversion to 5-substituted β-hydroxyketones in a…”
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Cytotoxic and Anti-Inflammatory Activities of Dihydroisocoumarin and Xanthone Derivatives from Garcinia picrorhiza
Published in Molecules (Basel, Switzerland) (01-11-2021)“…, a woody plant native to Sulawesi and Maluku Islands, Indonesia, has been traditionally used as a wound healing ointment. In our continuous search for…”
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UHPLC-MS Phytochemical Profiling and Insight into Bioactivity of Rabelera holostea (Greater Stitchwort) Extract
Published in Molecules (Basel, Switzerland) (28-01-2023)“…(L.) M. T. Sharples & E. A. Tripp (Greater Stitchwort), formerly known as L., is widespread in the warm temperate areas of Europe and Western Asia, the…”
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Identification of Constituents Affecting the Secretion of Pro-Inflammatory Cytokines in LPS-Induced U937 Cells by UHPLC-HRMS-Based Metabolic Profiling of the Traditional Chinese Medicine Formulation Huangqi Jianzhong Tang
Published in Molecules (Basel, Switzerland) (27-08-2019)“…Within non-communicable diseases, chronic inflammatory conditions represent one of the biggest challenges for modern medicine. Traditional Chinese Medicine…”
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Salvadora persica leaves: phytochemical profile and in vitro -inhibitory activity on inflammatory mediators implicated in periodontal disease
Published in Pharmaceutical biology (01-12-2024)“…Virtually all parts of L. (Salvadoraceae) are used in traditional medicine. The twigs and leaves are used for oral health, but leaves are far less…”
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Synthesis of Novel Shikonin Derivatives and Pharmacological Effects of Cyclopropylacetylshikonin on Melanoma Cells
Published in Molecules (Basel, Switzerland) (30-10-2018)“…Despite much research in the last centuries, treatment of malignant melanoma is still challenging because of its mostly unnoticeable metastatic spreading and…”
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A novel concept for detoxification: Complexation between aconitine and liquiritin in a Chinese herbal formula (‘Sini Tang’)
Published in Journal of ethnopharmacology (16-09-2013)“…Sini Tang (SNT, ▪) is a traditional Chinese herbal formulation consisting of three different herbs: Aconitum carmichaelii (Fuzi, ▪), Zingiber officinale…”
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