Search Results - "Bauer, Pál I."

Staurosporine induces necroptotic cell death under caspase-compromised conditions in U937 cells by Dunai, Zsuzsanna A, Imre, Gergely, Barna, Gabor, Korcsmaros, Tamas, Petak, Istvan, Bauer, Pal I, Mihalik, Rudolf

“…For a long time necrosis was thought to be an uncontrolled process but evidences recently have revealed that necrosis can also occur in a regulated manner…”
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The guanine-quadruplex structure in the human c-myc gene's promoter is converted into B-DNA form by the human poly(ADP-ribose)polymerase-1 by Fekete, Anna, Kenesi, Erzsebet, Hunyadi-Gulyas, Eva, Durgo, Hajnalka, Berko, Barbara, Dunai, Zsuzsanna A, Bauer, Pal I

“…The important regulatory role of the guanine-quadruplex (GQ) structure, present in the nuclease hypersensitive element (NHE) III(1) region of the human c-myc…”
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Necroptosis: Biochemical, Physiological and Pathological Aspects by Dunai, Zsuzsanna, Bauer, Pal I., Mihalik, Rudolf

“…Programmed cell death is a key component of tissue homeostasis, normal development and wide variety of diseases. Conventional view refers to programmed cell…”
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The somatostatin analogue TT-232 induces apoptosis in A431 cells: Sustained activation of stress-activated kinases and inhibition of signalling to extracellular signal-regulated kinases by Vántus, Tibor, Kéri, György, Krivickiene, Zita, Valius, Mindaugas, Steták, Attila, Keppens, Stefaan, Csermely, Péter, Bauer, Pál I, Bökönyi, Gyöngyi, Declercq, Wim, Vandenabeele, Peter, Merlevede, Wilfried, Vandenheede, Jackie R

“…TT-232 is a somatostatin analogue containing a five-residue ring structure. The present report describes TT-232-induced signalling events in A431 cells, where…”
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Dependence of trans‐ADP‐ribosylation and nuclear glycolysis on the Arg 34–ATP complex of Zn2+ finger I of poly‐ADP‐ribose polymerase‐1 by Kun, Ernest, Kirsten, Eva, Hakam, Alaeddin, Bauer, Pal I., Mendeleyev, Jerome

“…The supernatant of non‐malignant cells was replaced by glycolytic enzymes as ADP‐ribose acceptor. The hexokinase activity of the supernatant increased when…”
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Peptidyl β-homo-aspartals (3-amino-4-carboxybutyraldehydes): New specific inhibitors of caspases by Bajusz, Sándor, Fauszt, Irén, Németh, Klára, Barabás, Éva, Juhász, Attila, Patthy, Miklós, Bauer, Pál I.

“…Interleukin‐1β (IL‐1β)‐converting enzyme (ICE, caspase‐1) processes the IL‐1β precursor to mature inflammatory cytokine IL‐1β. ICE has been identified as a…”
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Regulation of malignant phenotype and bioenergetics by a π-electron donor-inducible mitochondrial MgATPase by Kun, Ernest, Mendeleyev, Jerome, Kirsten, Eva, Hakam, Alaeddin, Kun, Albert, Fekete, Anna, Bauer, Pal, Dunai, Zsuzsanna, Mihalik, Rudolf

“…The recognition of poly ADP-ribose transferase-1 (PARP-1) as an ATP sensor receiving this energy source by way of a specific adenylate kinase ATP wire (AK)…”
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Identification of poly(ADP-ribose) polymerase-1 as the OXPHOS-generated ATP sensor of nuclei of animal cells by Kun, Ernest, Kirsten, Eva, Hakam, Alaeddin, Bauer, Pal I., Mendeleyev, Jerome

“…Our results show that in the intact normal animal cell mitochondrial ATP is directly connected to nuclear PARP-1 by way of a specific adenylate kinase…”
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Quantitative correlation between cellular proliferation and nuclear poly (ADP-ribose) polymerase (PARP-1) by Kun, Ernest, Kirsten, Eva, Bauer, Pal, Ordahl, Charles

“…Treatment of cells with lysophosphatidyl choline and centrifugal extraction can separate poly (ADP-ribose) synthetase (PARP-1) and DNA synthetase activities,…”
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The influence of ATP on poly(ADP-ribose) metabolism by Bauer, Pal I, Kenesi, Erzsebet, Mendeleyev, Jerome, Kun, Ernest

“…ATP affects poly(ADP-ribose) metabolism at two distinct sites: it inhibits poly(ADP-ribose) polymerase-1 and activates the glycohydrolase directly. The…”
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Activation of deoxycytidine kinase by deoxyadenosine: Implications in deoxyadenosine-mediated cytotoxicity by Keszler, Gergely, Virga, Szula, Spasokoukotskaja, Tatjana, Bauer, Pal I., Sasvari-Szekely, Maria, Staub, Maria

“…The inborn deficiency of adenosine deaminase is characterised by accumulation of excess amounts of cytotoxic deoxyadenine nucleotides in lymphocytes. Formation…”
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Mechanisms of antitumor action of methyl-3,5-diiodo-4-(4'-methoxyphenoxy)benzoate: drug-induced protein dephosphorylations and inhibition of the permissive action of ceramide on growth factor induced cell proliferation by Bauer, Pal I, Kirsten, Eva, Kun, Ernest

“…The tumoricidal mechanism of methyl-3,5-diiodo-4-(4'-methoxypropoxy)benzoate (DIME), or DIPE, has been analyzed beyond its first recognized cellular site,…”
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Anti-cancer action of 4-iodo-3-nitrobenzamide in combination with buthionine sulfoximine: inactivation of poly(ADP-ribose) polymerase and tumor glycolysis and the appearance of a poly(ADP-ribose) polymerase protease by Bauer, Pal I, Mendeleyeva, Jerome, Kirsten, Eva, Comstock, John A, Hakam, Alaeddin, Buki, Kalman G, Kun, Ernest

“…E-ras 20 tumorigenic malignant cells and CV-1 non-tumorigenic cells were treated with a drug combination of 4-iodo-3-nitrobenzamide (INO 2BA) and buthionine…”
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Identification of Domains of Poly(ADP-ribose) Polymerase for Protein Binding and Self-association (∗) by Buki, Kalman G., Bauer, Pal I., Hakam, Alaeddin, Kun, Ernest

“…Cellular proteins extracted from normal and cancer cells bind polymerizing ADP-ribose transferase (pADPRT) on nitrocellulose membrane transblots. Histones at 1…”
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BCNU is a caspase-mediated inhibitor of drug-induced apoptosis by PETAK, I, MIHALIK, R, BAUER, P. I, SÜLI-VARGHA, H, SEBESTYEN, A, KOPPER, L

“…BCNU [1,3-bis(2-chloroethyl)-1-nitrosourea], a bifunctional (alkylating/carbamoylating) anticancer agent, in noncytotoxic doses (12-50 microM) inhibited…”
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The Guanine-Quadruplex Structure in the Human c-myc Gene's Promoter Is Converted into B-DNA Form by the Human Poly by Fekete, Anna, Kenesi, Erzsebet, Hunyadi-Gulyas, Eva, Durgo, Hajnalka, Berko, Barbara, Dunai, Zsuzsanna A, Bauer, Pal I

“…The important regulatory role of the guanine-quadruplex (GQ) structure, present in the nuclease hypersensitive element (NHE) III.sub.1 region of the human…”
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The Guanine-Quadruplex Structure in the Human c-myc Gene's Promoter Is Converted into B-DNA Form by the Human PolyPolymerase-1 by Fekete, Anna, Kenesi, Erzsebet, Hunyadi-Gulyas, Eva, Durgo, Hajnalka, Berko, Barbara, Dunai, Zsuzsanna A, Bauer, Pal I

“…The important regulatory role of the guanine-quadruplex (GQ) structure, present in the nuclease hypersensitive element (NHE) III.sub.1 region of the human…”
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The somatostatin analogue TT-232 induces apoptosis in A431 cells by Vántus, Tibor, Kéri, György, Krivickiene, Zita, Valius, Mindaugas, Steták, Attila, Keppens, Stefaan, Csermely, Péter, Bauer, Pál I, Bökönyi, Gyöngyi, Declercq, Wim, Vandenabeele, Peter, Merlevede, Wilfried, Vandenheede, Jackie R

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Dependence of trans-ADP-ribosylation and nuclear glycolysis on the Arg 34–ATP complex of Zn 2+ finger I of poly-ADP-ribose polymerase-1 by Kun, Ernest, Kirsten, Eva, Hakam, Alaeddin, Bauer, Pal I., Mendeleyev, Jerome

“…The H-bonded complex of ATP with Arg 34 of Zn 2+ finger I of poly-ADP-ribose polymerase-1 (PARP-1) determines trans-oligo-ADP-ribosylation from NAD + to…”
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Apoptotic cell death induced by inhibitors of energy conservation--Bcl-2 inhibits apoptosis downstream of a fall of ATP level by Marton, A, Mihalik, R, Bratincsák, A, Adleff, V, Peták, I, Végh, M, Bauer, P I, Krajcsi, P

“…Energy charge controls intermediary metabolism and cellular regulation. Here we show that inhibition of energy conservation at the level of glucose uptake,…”
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