Search Results - "Bauer, Moises E."
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The theory of bipolar disorder as an illness of accelerated aging: Implications for clinical care and research
Published in Neuroscience and biobehavioral reviews (01-05-2014)“…Bipolar Disorder (BD) has been conceptualized as both a cyclic and a progressive disorder. Mechanisms involved in neuroprogression in BD remain largely unknown…”
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Inflammation in psychiatric disorders: what comes first?
Published in Annals of the New York Academy of Sciences (01-02-2019)“…Neuropsychiatric disorders (i.e., mood disorders and schizophrenia) and inflammation are closely intertwined, and possibly powering each other in a…”
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Plasma Levels of Tumor Necrosis Factor Superfamily Molecules Are Increased in Bipolar Disorder
Published in Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology (31-08-2017)“…Patients with bipolar disorder (BD) exhibit peripheral low-grade inflammation. The aim of the current study was to investigate the involvement of hitherto…”
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Accelerated immunosenescence in rheumatoid arthritis: impact on clinical progression
Published in Immunity & ageing (09-03-2020)“…Patients with rheumatoid arthritis (RA) develop features of accelerated ageing, including immunosenescence. These changes include decreased thymic…”
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Revisiting inflammation in bipolar disorder
Published in Pharmacology, biochemistry and behavior (01-02-2019)“…Bipolar disorder (BD) has been associated with immune changes, and yet their underlying mechanisms are still not fully understood. Here, we review the current…”
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Further evidence of accelerated aging in bipolar disorder: Focus on GDF-15
Published in Translational neuroscience (01-01-2018)“…Bipolar disorder (BD) is a mood disorder associated with cardiovascular and metabolic diseases and premature aging. Growth differentiation factor 15 (GDF-15)…”
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The interplay between immunosenescence and age-related diseases
Published in Seminars in immunopathology (01-10-2020)“…The aging immune system (immunosenescence) has been implicated with increased morbidity and mortality in the elderly. Of note, T cell aging and low-grade…”
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Neuroimmunology and ageing - the state of the art
Published in Immunity & ageing (10-01-2024)“…Inflammaging is a low level pro-inflammatory state which is believed to be a major contributor to biological aging which underlies many age-associated…”
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Is steroid resistance related to multidrug resistance-I (MDR-I) in rheumatoid arthritis?
Published in International immunopharmacology (01-06-2007)“…Both healthy ageing and rheumatoid arthritis (RA) are frequently associated with acquired steroid resistance. Here, we investigated the potential involvement…”
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Neuroendocrine and viral correlates of premature immunosenescence
Published in Annals of the New York Academy of Sciences (01-09-2015)“…Aging continuously remodels the immune system, a process known as immunosenescence. Here, we review evidence of premature immunosenescence in younger…”
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The Role of Stress Factors during Aging of the Immune System
Published in Annals of the New York Academy of Sciences (01-02-2009)“…This manuscript reviews current evidence suggesting that aging of the immune system (immunosenescence) may be closely related to chronic stress and stress…”
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Cocaine Use Disorder Is Associated With Changes in Th1/Th2/Th17 Cytokines and Lymphocytes Subsets
Published in Frontiers in immunology (15-10-2019)“…Cocaine is a psychostimulant drug with high addictive proprieties. Evidence suggests that cocaine use leads to critical changes in the immune system, with…”
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Peripheral leukocyte profile in people with temporal lobe epilepsy reflects the associated proinflammatory state
Published in Brain, behavior, and immunity (01-03-2016)“…Highlights • Immune cells of temporal lobe epilepsy (TLE) people show an activation profile. • Regulatory T cells produced significantly more IL-10 in people…”
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Distress conditions during pregnancy may lead to pre-eclampsia by increasing cortisol levels and altering lymphocyte sensitivity to glucocorticoids
Published in Medical hypotheses (01-08-2011)“…Abstract Psychological stress may affect up to 18% of all pregnant women, altering the function of both neuroendocrine and immune systems. Distress conditions…”
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Cocaine-use disorder and childhood maltreatment are associated with the activation of neutrophils and increased inflammation
Published in Acta neuropsychiatrica (01-04-2024)“…Cocaine-use disorder (CUD) has been associated with early life adversity and activated cellular immune responses. Women are most vulnerable to complications…”
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HLA-G and CD8+ regulatory T cells in the inflammatory environment of pre-eclampsia
Published in Reproduction (Cambridge, England) (01-12-2016)“…During pregnancy, the maternal immune system is tolerant to foetal antigens via the engagement of immune regulatory mechanisms. Failure in regulating the…”
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Early abstinence of crack-cocaine is effective to attenuate oxidative stress and to improve antioxidant defences
Published in Psychopharmacology (01-04-2015)“…Rationale Preclinical studies have shown that cocaine exposure and withdrawal are associated with cellular oxidative stress damage. However, the impact of…”
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Early life stress and tumor necrosis factor superfamily in crack cocaine withdrawal
Published in Journal of psychiatric research (01-06-2014)“…Abstract Background Both early life stress (ELS) and substance abuse, especially cocaine, have robust effects on the inflammatory system. Considering the role…”
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An immunological age index in bipolar disorder: A confirmatory factor analysis of putative immunosenescence markers and associations with clinical characteristics
Published in International journal of methods in psychiatric research (01-12-2018)“…Objectives The study aims to generate an immunological age (IA) trait on the basis of immune cell differentiation parameters, and to test whether the IA is…”
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Increased soluble tumor necrosis factor‐α receptors in patients with major depressive disorder
Published in Psychiatry and clinical neurosciences (01-04-2009)“…Aim: Several lines of evidence suggest that major depressive disorder is associated with an inflammatory status. Tumor necrosis factor‐α has been investigated…”
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