Search Results - "Bauer, Maria A."
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Spermidine: a physiological autophagy inducer acting as an anti-aging vitamin in humans?
Published in Autophagy (02-01-2019)“…Spermidine is a natural polyamine that stimulates cytoprotective macroautophagy/autophagy. External supplementation of spermidine extends lifespan and health…”
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2
Fungal infections in humans: the silent crisis
Published in Microbial cell (01-06-2020)“…Annually, over 150 million severe cases of fungal infections occur worldwide, resulting in approximately 1.7 million deaths per year. Alarmingly, these numbers…”
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3
Microbial wars: Competition in ecological niches and within the microbiome
Published in Microbial cell (07-05-2018)“…Many microbial communities live in highly competitive surroundings, in which the fight for resources determines their survival and genetic persistence. Humans…”
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Nutritional Aspects of Spermidine
Published in Annual review of nutrition (23-09-2020)“…Natural polyamines (spermidine and spermine) are small, positively charged molecules that are ubiquitously found within organisms and cells. They exert…”
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5
Digesting the crisis: autophagy and coronaviruses
Published in Microbial cell (04-05-2020)“…Autophagy is a catabolic pathway with multifaceted roles in cellular homeostasis. This process is also involved in the antiviral response at multiple levels,…”
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The rise of Candida auris: from unique traits to co-infection potential
Published in Microbial cell (01-08-2022)“…Candida auris is a multidrug resistant (MDR) fungal pathogen with a crude mortality rate of 30-60%. First identified in 2009, C. auris has been rapidly rising…”
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7
Studying Huntington's Disease in Yeast: From Mechanisms to Pharmacological Approaches
Published in Frontiers in molecular neuroscience (04-09-2018)“…Huntington's disease (HD) is a neurodegenerative disorder that leads to progressive neuronal loss, provoking impaired motor control, cognitive decline, and…”
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Murals meet microbes: at the crossroads of microbiology and cultural heritage
Published in Microbial cell (06-12-2021)“…Our cultural heritage consists of manifold cultural expressions and represents a defining feature of our societies that needs to be further inherited to future…”
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A hundred spotlights on microbiology: how microorganisms shape our lives
Published in Microbial cell (04-04-2022)“…Viral, bacterial, fungal and protozoal biology is of cardinal importance for the evolutionary history of life, ecology, biotechnology and infectious diseases…”
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10
When less is more: hormesis against stress and disease
Published in Microbial cell (05-05-2014)“…All living organisms need to adapt to ever changing adverse conditions in order to survive. The phenomenon termed hormesis describes an evolutionarily…”
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Targeting GATA transcription factors - a novel strategy for anti-aging interventions?
Published in Microbial cell (06-05-2019)“…GATA transcription factors (TFs) are a conserved family of zinc-finger TFs that fulfill diverse functions across eukaryotes. Accumulating evidence suggests…”
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12
Ceramide triggers metacaspase-independent mitochondrial cell death in yeast
Published in Cell cycle (Georgetown, Tex.) (15-11-2011)“…The activation of ceramide-generating enzymes, the blockade of ceramide degradation, or the addition of ceramide analogues can trigger apoptosis or necrosis in…”
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Transcriptional and epigenetic control of regulated cell death in yeast
Published in International review of cell and molecular biology (2020)“…Unicellular organisms like yeast can undergo controlled demise in a manner that is partly reminiscent of mammalian cell death. This is true at the levels of…”
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Assessing chronological aging in Saccharomyces cerevisiae
Published in Cellular Senescence and Aging (2024)“…Chronological age represents the time that passes between birth and a given date. To understand the complex network of factors contributing to chronological…”
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Book Chapter Journal Article -
15
4,4'Dimethoxychalcone: a natural flavonoid that promotes health through autophagy-dependent and -independent effects
Published in Autophagy (02-09-2019)“…The age-induced deterioration of the organism results in detrimental and ultimately lethal pathologies. The process of aging itself involves a plethora of…”
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The flavonoid 4,4′-dimethoxychalcone promotes autophagy-dependent longevity across species
Published in Nature communications (19-02-2019)“…Ageing constitutes the most important risk factor for all major chronic ailments, including malignant, cardiovascular and neurodegenerative diseases. However,…”
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