Search Results - "Bauer, Karl E."

RNA supply drives physiological granule assembly in neurons by Bauer, Karl E., Bargenda, Niklas, Schieweck, Rico, Illig, Christin, Segura, Inmaculada, Harner, Max, Kiebler, Michael A.

“…Membraneless cytoplasmic condensates of mRNAs and proteins, known as RNA granules, play pivotal roles in the regulation of mRNA fate. Their maintenance…”
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Synaptically-targeted long non-coding RNA SLAMR promotes structural plasticity by increasing translation and CaMKII activity by Espadas, Isabel, Wingfield, Jenna L., Nakahata, Yoshihisa, Chanda, Kaushik, Grinman, Eddie, Ghosh, Ilika, Bauer, Karl E., Raveendra, Bindu, Kiebler, Michael A., Yasuda, Ryohei, Rangaraju, Vidhya, Puthanveettil, Sathyanarayanan

“…Long noncoding RNAs (lncRNAs) play crucial roles in maintaining cell homeostasis and function. However, it remains largely unknown whether and how neuronal…”
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Live cell imaging reveals 3′-UTR dependent mRNA sorting to synapses by Bauer, Karl E., Segura, Inmaculada, Gaspar, Imre, Scheuss, Volker, Illig, Christin, Ammer, Georg, Hutten, Saskia, Basyuk, Eugénia, Fernández-Moya, Sandra M., Ehses, Janina, Bertrand, Edouard, Kiebler, Michael A.

“…mRNA transport restricts translation to specific subcellular locations, which is the basis for many cellular functions. However, the precise process of mRNA…”
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Interactome of Two Diverse RNA Granules Links mRNA Localization to Translational Repression in Neurons by Fritzsche, Renate, Karra, Daniela, Bennett, Keiryn L., Ang, Foong yee, Heraud-Farlow, Jacki E., Tolino, Marco, Doyle, Michael, Bauer, Karl E., Thomas, Sabine, Planyavsky, Melanie, Arn, Eric, Bakosova, Anetta, Jungwirth, Kerstin, Hörmann, Alexandra, Palfi, Zsofia, Sandholzer, Julia, Schwarz, Martina, Macchi, Paolo, Colinge, Jacques, Superti-Furga, Giulio, Kiebler, Michael A.

“…Transport of RNAs to dendrites occurs in neuronal RNA granules, which allows local synthesis of specific proteins at active synapses on demand, thereby…”
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Meet the players: local translation at the synapse by Fernandez-Moya, Sandra M, Bauer, Karl E, Kiebler, Michael A

“…It is widely believed that activity-dependent synaptic plasticity is the basis for learning and memory. Both processes are dependent on new protein synthesis…”
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RGS4 RNA Secondary Structure Mediates Staufen2 RNP Assembly in Neurons by Fernández-Moya, Sandra M, Ehses, Janina, Bauer, Karl E, Schieweck, Rico, Chakrabarti, Anob M, Lee, Flora C Y, Illig, Christin, Luscombe, Nicholas M, Harner, Max, Ule, Jernej, Kiebler, Michael A

“…RNA-binding proteins (RBPs) act as posttranscriptional regulators controlling the fate of target mRNAs. Unraveling how RNAs are recognized by RBPs and in turn…”
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RNA granules in flux: dynamics to balance physiology and pathology by Kiebler, Michael A., Bauer, Karl E.

“…The life cycle of an mRNA is a complex process that is tightly regulated by interactions between the mRNA and RNA-binding proteins, forming molecular machines…”
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RNA granules in neuronal plasticity and disease by Bauer, Karl E., de Queiroz, Bruna R., Kiebler, Michael A., Besse, Florence

“…Selected RNA-binding proteins self-assemble together with their cognate RNAs in a dynamic and controlled manner into neuronal RNA granules.These RNA…”
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Visualizing RNA granule transport and translation in living neurons by Bauer, Karl E., Kiebler, Michael A., Segura, Inmaculada

“…•Visualization of RNA granule transport in living cells.•Simultaneous detection of co-migrating RNAs and proteins.•Visualization of dendritic translation…”
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Pumilio2 and Staufen2 selectively balance the synaptic proteome by Schieweck, Rico, Riedemann, Therese, Forné, Ignasi, Harner, Max, Bauer, Karl E., Rieger, Daniela, Ang, Foong yee, Hutten, Saskia, Demleitner, Antonia F., Popper, Bastian, Derdak, Sophia, Sutor, Bernd, Bilban, Martin, Imhof, Axel, Kiebler, Michael A.

“…Neurons have the capacity to adapt to environmental stimuli, a phenomenon termed cellular plasticity. The underlying processes are controlled by a network of…”
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