Search Results - "Bauer, Karin E."

Isoenzyme-specific glutathione-S-transferase inhibitors: design and synthesis by Lyttle, Matthew H, Hocker, Michael D, Hui, Hon C, Caldwell, Colby G, Aaron, Decius T, Engqvist-Goldstein, Asa, Flatgaard, Jeffrey E, Bauer, Karin E

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Glutathione-S-transferase Activates Novel Alkylating Agents by Lyttle, Matthew H, Satyam, Apparao, Hocker, Michael D, Bauer, Karin E, Caldwell, Colby G, Hui, Hon C, Morgan, Amy S, Mergia, Alemayehu, Kauvar, Lawrence M

“…Alkylating agents which are activated by glutathion-S-transferases (GSTs) have been designed and synthesized. The model compound…”
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Ligand-based protein alignment and isozyme specificity of glutathione S-transferase inhibitors by Koehler, Ryan T., Villar, Hugo O., Bauer, Karin E., Higgins, Deborah L.

“…Glutathione S‐transferases (GST, E.C.2.5.1.18) comprise a family of detoxification enzymes. Elevated levels of specific GST isozymes in tumor cells are thought…”
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Ligand-based protein alignment and isozyme specificity of glutathioneS-transferase inhibitors by Koehler, Ryan T., Villar, Hugo O., Bauer, Karin E., Higgins, Deborah L.

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Isozyme specificity of novel glutathione-S-transferase inhibitors by FLATGAARD, J. E, BAUER, K. E, KAUVAR, L. M

“…A systematically diversified set of peptide analogs of the reaction product of glutathione with an electrophilic substrate have been tested as isozyme-specific…”
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Predicting ligand binding to proteins by affinity fingerprinting by Kauvar, Lawrence M., Higgins, Deborah L., Villar, Hugo O., Sportsman, J.Richard, Engqvist-Goldstein, Åsa, Bukar, Robert, Bauer, Karin E., Dilley, Hara, Rocke, David M.

“…Background: There are many ways to represent a molecule's properties, including atomic-connectivity drawings. NMR spectra, and molecular orbital models. Prior…”
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