Search Results - "Bauer, Johann Wolfgang"

Identifying drug allergies by means of exposure testing - the frequency and nature of hypersensitivity reactions by Welponer, Tobias, Brandlmaier, Matthias, Feuerstein, Bernd, Bauer, Johann W

“…Drug hypersensitivity reactions are dose-independent, unpredictable, and immune-mediated type B adverse drug reactions (ADR) in patients sensitized to a…”
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A non-viral and selection-free COL7A1 HDR approach with improved safety profile for dystrophic epidermolysis bullosa by Kocher, Thomas, Bischof, Johannes, Haas, Simone Alexandra, March, Oliver Patrick, Liemberger, Bernadette, Hainzl, Stefan, Illmer, Julia, Hoog, Anna, Muigg, Katharina, Binder, Heide-Marie, Klausegger, Alfred, Strunk, Dirk, Bauer, Johann Wolfgang, Cathomen, Toni, Koller, Ulrich

“…Gene editing via homology-directed repair (HDR) currently comprises the best strategy to obtain perfect corrections for pathogenic mutations of monogenic…”
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COL17A1 editing via homology-directed repair in junctional epidermolysis bullosa by Petković, Igor, Bischof, Johannes, Kocher, Thomas, March, Oliver Patrick, Liemberger, Bernadette, Hainzl, Stefan, Strunk, Dirk, Raninger, Anna Maria, Binder, Heide-Marie, Reichelt, Julia, Guttmann-Gruber, Christina, Wally, Verena, Piñón Hofbauer, Josefina, Bauer, Johann Wolfgang, Koller, Ulrich

“…Background Epidermolysis bullosa (EB), a severe genetic disorder characterized by blister formation in skin, is caused by mutations in genes encoding…”
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Recessive Dystrophic Epidermolysis bullosa due to Hemizygous 40 kb Deletion of COL7A1 and the Proximate PFKFB4 Gene Focusing on the Mutation c.425A>G Mimicking Homozygous Status by Klausegger, Alfred, Jeschko, Niklas, Grammer, Markus, Cemper-Kiesslich, Jan, Neuhuber, Franz, Diem, Anja, Breitenbach-Koller, Hannelore, Sander, Gabriele, Kotzot, Dieter, Bauer, Johann Wolfgang, Laimer, Martin

“…Background: Dystrophic Epidermolysis bullosa (DEB) is a rare inherited mechanobullous disease characterised by the hyperfragility of the skin and mucous…”
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Loss of efficacy of topical 5% permethrin for treating scabies: an Austrian single-center study by Meyersburg, Damian, Kaiser, Andreas, Bauer, Johann Wolfgang

“…Scabies is a contagious, itchy, parasitic infection of the skin. It is transmitted by skin-to-skin contact or by contact with contaminated material. Recent…”
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Predictable CRISPR/Cas9-Mediated COL7A1 Reframing for Dystrophic Epidermolysis Bullosa by Kocher, Thomas, March, Oliver Patrick, Bischof, Johannes, Liemberger, Bernadette, Hainzl, Stefan, Klausegger, Alfred, Hoog, Anna, Strunk, Dirk, Bauer, Johann Wolfgang, Koller, Ulrich

“…End-joining‒based gene editing is frequently used for efficient reframing and knockout of target genes. However, the associated random, unpredictable, and…”
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Cut and Paste: Efficient Homology-Directed Repair of a Dominant Negative KRT14 Mutation via CRISPR/Cas9 Nickases by Kocher, Thomas, Peking, Patricia, Klausegger, Alfred, Murauer, Eva Maria, Hofbauer, Josefina Piñón, Wally, Verena, Lettner, Thomas, Hainzl, Stefan, Ablinger, Michael, Bauer, Johann Wolfgang, Reichelt, Julia, Koller, Ulrich

“…With the ability to induce rapid and efficient repair of disease-causing mutations, CRISPR/Cas9 technology is ideally suited for gene therapy approaches for…”
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How to analyze continuous and discrete repeated measures in small‐sample cross‐over trials? by Verbeeck, Johan, Geroldinger, Martin, Thiel, Konstantin, Hooker, Andrew Craig, Ueckert, Sebastian, Karlsson, Mats, Bathke, Arne Cornelius, Bauer, Johann Wolfgang, Molenberghs, Geert, Zimmermann, Georg

“…To optimize the use of data from a small number of subjects in rare disease trials, an at first sight advantageous design is the repeated measures cross‐over…”
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Paired nicking-mediated COL17A1 reframing for junctional epidermolysis bullosa by Bischof, Johannes, March, Oliver Patrick, Liemberger, Bernadette, Haas, Simone Alexandra, Hainzl, Stefan, Petković, Igor, Leb-Reichl, Victoria, Illmer, Julia, Korotchenko, Evgeniia, Klausegger, Alfred, Hoog, Anna, Binder, Heide-Marie, Garcia, Marta, Duarte, Blanca, Strunk, Dirk, Larcher, Fernando, Reichelt, Julia, Guttmann-Gruber, Christina, Wally, Verena, Hofbauer, Josefina Piñón, Bauer, Johann Wolfgang, Cathomen, Toni, Kocher, Thomas, Koller, Ulrich

“…Junctional epidermolysis bullosa (JEB) is a debilitating hereditary skin disorder caused by mutations in genes encoding laminin-332, type XVII collagen (C17),…”
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Recessive Dystrophic IEpidermolysis bullosa/I due to Hemizygous 40 kb Deletion of ICOL7A1/I and the Proximate IPFKFB4/I Gene Focusing on the Mutation c.425AG Mimicking Homozygous Status by Klausegger, Alfred, Jeschko, Niklas, Grammer, Markus, Cemper-Kiesslich, Jan, Neuhuber, Franz, Diem, Anja, Breitenbach-Koller, Hannelore, Sander, Gabriele, Kotzot, Dieter, Bauer, Johann Wolfgang, Laimer, Ma

“…Background: Dystrophic Epidermolysis bullosa (DEB) is a rare inherited mechanobullous disease characterised by the hyperfragility of the skin and mucous…”
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