Search Results - "Baud, Stéphanie"
-
1
Proteoglycan Chemical Diversity Drives Multifunctional Cell Regulation and Therapeutics
Published in Chemical reviews (26-09-2018)“…The extracellular matrix (ECM) constitutes a highly dynamic three-dimensional structural network comprised of macromolecules, such as…”
Get full text
Journal Article -
2
Structural impact of a new spike Y170W mutation detected in early emerging SARS-CoV-2 Omicron variants in France
Published in Virus research (01-05-2024)“…•NGS detection of a new mutations in early emerging SARS-CoV-2 Omicron variant.•Weakly and transient Y170W spike mutation during emergence of Omicron…”
Get full text
Journal Article -
3
Small leucine-rich proteoglycans and matrix metalloproteinase-14: Key partners?
Published in Matrix biology (01-01-2019)“…Small leucine-rich proteoglycans (SLRPs) are important regulators of extracellular matrix assembly and cell signaling. They are a family of proteoglycans that…”
Get full text
Journal Article -
4
Elastin-Derived Peptides Are New Regulators of Insulin Resistance Development in Mice
Published in Diabetes (New York, N.Y.) (01-11-2013)“…Although it has long been established that the extracellular matrix acts as a mechanical support, its degradation products, which mainly accumulate during…”
Get full text
Journal Article -
5
AMIDE v2: High-Throughput Screening Based on AutoDock-GPU and Improved Workflow Leading to Better Performance and Reliability
Published in International journal of molecular sciences (13-07-2021)“…Molecular docking is widely used in computed drug discovery and biological target identification, but getting fast results can be tedious and often requires…”
Get full text
Journal Article -
6
Early Alterations of Intra-Mural Elastic Lamellae Revealed by Synchrotron X-ray Micro-CT Exploration of Diabetic Aortas
Published in International journal of molecular sciences (17-03-2022)“…Diabetes is a major concern of our society as it affects one person out of 11 around the world. Elastic fiber alterations due to diabetes increase the…”
Get full text
Journal Article -
7
Sialic acids cleavage induced by elastin-derived peptides impairs the interaction between insulin and its receptor in adipocytes 3T3-L1
Published in Journal of physiology and biochemistry (01-05-2024)“…The insulin receptor (IR) plays an important role in insulin signal transduction, the defect of which is believed to be the root cause of type 2 diabetes. In…”
Get full text
Journal Article -
8
Impact of sialic acids on the molecular dynamic of bi-antennary and tri-antennary glycans
Published in Scientific reports (19-10-2016)“…Sialic acids (SA) are monosaccharides that can be located at the terminal position of glycan chains on a wide range of proteins. The post-translational…”
Get full text
Journal Article -
9
Anti-Toxoplasma gondii effect of lupane-type triterpenes from the bark of black alder (Alnus glutinosa) and identification of a potential target by reverse docking
Published in Parasite (Paris) (2022)“…Toxoplasmosis is a worldwide parasitosis that is generally benign. The infestation may pose a risk to immunocompromized patients and to fetuses when pregnant…”
Get full text
Journal Article -
10
Conformation-dependent binding of a Tetrastatin peptide to αvβ3 integrin decreases melanoma progression through FAK/PI3K/Akt pathway inhibition
Published in Scientific reports (29-06-2018)“…Tetrastatin, a 230 amino acid sequence from collagen IV, was previously demonstrated to inhibit melanoma progression. In the present paper, we identified the…”
Get full text
Journal Article -
11
Structural Analysis of Nonapeptides Derived from Elastin
Published in Biophysical journal (02-06-2020)“…Elastin-derived peptides are released from the extracellular matrix remodeling by numerous proteases and seem to regulate many biological processes, notably…”
Get full text
Journal Article -
12
AG-9, an Elastin-Derived Peptide, Increases In Vitro Oral Tongue Carcinoma Cell Invasion, through an Increase in MMP-2 Secretion and MT1-MMP Expression, in a RPSA-Dependent Manner
Published in Biomolecules (Basel, Switzerland) (01-01-2021)“…Oral tongue squamous cell carcinoma is one of the most prevalent head and neck cancers. During tumor progression, elastin fragments are released in the tumor…”
Get full text
Journal Article -
13
New Insights into Molecular Organization of Human Neuraminidase-1: Transmembrane Topology and Dimerization Ability
Published in Scientific reports (05-12-2016)“…Neuraminidase 1 (NEU1) is a lysosomal sialidase catalyzing the removal of terminal sialic acids from sialyloconjugates. A plasma membrane-bound NEU1 modulating…”
Get full text
Journal Article -
14
Binding of Inositol Stereoisomers To Model Amyloidogenic Peptides
Published in The journal of physical chemistry. B (26-01-2012)“…The self-aggregation of proteins into amyloid fibrils is a pathological hallmark of numerous incurable diseases such as Alzheimer’s disease. scyllo-Inositol is…”
Get full text
Journal Article -
15
Differential MMP-14 Targeting by Lumican-Derived Peptides Unraveled by In Silico Approach
Published in Cancers (30-09-2021)“…Lumican, a small leucine-rich proteoglycan (SLRP) of the extracellular matrix (ECM), displays anti-tumor properties through its direct interaction with MMP-14…”
Get full text
Journal Article -
16
A Fully Automatic and Efficient Methodology for Peptide Activity Identification Using Their 3D Conformations
Published in IEEE access (2021)“…Over the past decades, the understanding of peptides and proteins biological functions has been an active research topic. Latest research works in this field…”
Get full text
Journal Article -
17
Interaction between the Elastin Peptide VGVAPG and Human Elastin Binding Protein
Published in The Journal of biological chemistry (11-01-2013)“…The elastin binding protein (EBP), a spliced variant of lysosomal β-galactosidase, is the primary receptor of elastin peptides that have been linked to…”
Get full text
Journal Article -
18
Transmembrane Peptides as a New Strategy to Inhibit Neuraminidase-1 Activation
Published in Frontiers in cell and developmental biology (16-12-2020)“…Sialidases, or neuraminidases, are involved in several human disorders such as neurodegenerative, infectious and cardiovascular diseases, and cancers…”
Get full text
Journal Article -
19
Machine-learning methods for ligand–protein molecular docking
Published in Drug discovery today (01-01-2022)“…•Comparative review of molecular docking scoring methods, with and without machine learning.•Analysis of most common data representation methods.•General…”
Get full text
Journal Article -
20
Mesoscopic Rigid Body Modelling of the Extracellular Matrix Self-Assembly
Published in Journal of integrative bioinformatics (11-06-2018)“…The extracellular matrix (ECM) plays an important role in supporting tissues and organs. It even has a functional role in morphogenesis and differentiation by…”
Get full text
Journal Article