Search Results - "Batzer, A."

The impact of retrotransposons on human genome evolution by Batzer, Mark A, Cordaux, Richard

“…Key Points LINE-1 (L1), Alu and SVA elements belong to the non-long terminal repeat retrotransposon class of transposable elements, and they account for…”
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Repetitive elements may comprise over two-thirds of the human genome by de Koning, A P Jason, Gu, Wanjun, Castoe, Todd A, Batzer, Mark A, Pollock, David D

“…Transposable elements (TEs) are conventionally identified in eukaryotic genomes by alignment to consensus element sequences. Using this approach, about half of…”
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Mobile elements create structural variation: analysis of a complete human genome by Xing, Jinchuan, Zhang, Yuhua, Han, Kyudong, Salem, Abdel Halim, Sen, Shurjo K, Huff, Chad D, Zhou, Qiong, Kirkness, Ewen F, Levy, Samuel, Batzer, Mark A, Jorde, Lynn B

“…Structural variants (SVs) are common in the human genome. Because approximately half of the human genome consists of repetitive, transposable DNA sequences, it…”
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Birth of a Chimeric Primate Gene by Capture of the Transposase Gene from a Mobile Element by Cordaux, Richard, Udit, Swalpa, Batzer, Mark A., Feschotte, Cédric

“…The emergence of new genes and functions is of central importance to the evolution of species. The contribution of various types of duplications to genetic…”
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Genetic Similarities Within and Between Human Populations by Witherspoon, D. J, Wooding, S, Rogers, A. R, Marchani, E. E, Watkins, W. S, Batzer, M. A, Jorde, L. B

“…The proportion of human genetic variation due to differences between populations is modest, and individuals from different populations can be genetically more…”
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L1 recombination-associated deletions generate human genomic variation by Han, Kyudong, Lee, Jungnam, Meyer, Thomas J, Remedios, Paul, Goodwin, Lindsey, Batzer, Mark A

“…Mobile elements have created structural variation in the human genome through their de novo insertions and post-insertional genomic rearrangements. L1 elements…”
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Mammalian retroelements by Deininger, Prescott L, Batzer, Mark A

“…The eukaryotic genome has undergone a series of epidemics of amplification of mobile elements that have resulted in most eukaryotic genomes containing much…”
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Alu repeats and human genomic diversity by Batzer, Mark A, Deininger, Prescott L

“…During the past 65 million years, Alu elements have propagated to more than one million copies in primate genomes, which has resulted in the generation of a…”
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A comprehensive map of mobile element insertion polymorphisms in humans by Stewart, Chip, Kural, Deniz, Strömberg, Michael P, Walker, Jerilyn A, Konkel, Miriam K, Stütz, Adrian M, Urban, Alexander E, Grubert, Fabian, Lam, Hugo Y K, Lee, Wan-Ping, Busby, Michele, Indap, Amit R, Garrison, Erik, Huff, Chad, Xing, Jinchuan, Snyder, Michael P, Jorde, Lynn B, Batzer, Mark A, Korbel, Jan O, Marth, Gabor T

“…As a consequence of the accumulation of insertion events over evolutionary time, mobile elements now comprise nearly half of the human genome. The Alu, L1, and…”
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Reading TE leaves: new approaches to the identification of transposable element insertions by Ray, David A, Batzer, Mark A

“…Transposable elements (TEs) are a tremendous source of genome instability and genetic variation. Of particular interest to investigators of human biology and…”
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Chromosomal inversions between human and chimpanzee lineages caused by retrotransposons by Lee, Jungnam, Han, Kyudong, Meyer, Thomas J, Kim, Heui-Soo, Batzer, Mark A

“…The long interspersed element-1 (LINE-1 or L1) and Alu elements are the most abundant mobile elements comprising 21% and 11% of the human genome, respectively…”
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Tangram: a comprehensive toolbox for mobile element insertion detection by Wu, Jiantao, Lee, Wan-Ping, Ward, Alistair, Walker, Jerilyn A, Konkel, Miriam K, Batzer, Mark A, Marth, Gabor T

“…Mobile elements (MEs) constitute greater than 50% of the human genome as a result of repeated insertion events during human genome evolution. Although most of…”
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5'-Transducing SVA retrotransposon groups spread efficiently throughout the human genome by Damert, Annette, Raiz, Julija, Horn, Axel V, Löwer, Johannes, Wang, Hui, Xing, Jinchuan, Batzer, Mark A, Löwer, Roswitha, Schumann, Gerald G

“…SVA elements represent the youngest family of hominid non-LTR retrotransposons, which alter the human genome continuously. They stand out due to their…”
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dbRIP: A highly integrated database of retrotransposon insertion polymorphisms in humans by Wang, Jianxin, Song, Lei, Grover, Deepak, Azrak, Sami, Batzer, Mark A., Liang, Ping

“…Retrotransposons constitute over 40% of the human genome and play important roles in the evolution of the genome. Since certain types of retrotransposons,…”
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An integrated map of structural variation in 2,504 human genomes by Sudmant, Peter H., Rausch, Tobias, Gardner, Eugene J., Handsaker, Robert E., Abyzov, Alexej, Huddleston, John, Zhang, Yan, Ye, Kai, Jun, Goo, Hsi-Yang Fritz, Markus, Konkel, Miriam K., Malhotra, Ankit, Stütz, Adrian M., Shi, Xinghua, Paolo Casale, Francesco, Chen, Jieming, Hormozdiari, Fereydoun, Dayama, Gargi, Chen, Ken, Malig, Maika, Chaisson, Mark J. P., Walter, Klaudia, Meiers, Sascha, Kashin, Seva, Garrison, Erik, Auton, Adam, Lam, Hugo Y. K., Jasmine Mu, Xinmeng, Alkan, Can, Antaki, Danny, Bae, Taejeong, Cerveira, Eliza, Chines, Peter, Chong, Zechen, Clarke, Laura, Dal, Elif, Ding, Li, Emery, Sarah, Fan, Xian, Gujral, Madhusudan, Kahveci, Fatma, Kidd, Jeffrey M., Kong, Yu, Lameijer, Eric-Wubbo, McCarthy, Shane, Flicek, Paul, Gibbs, Richard A., Marth, Gabor, Mason, Christopher E., Menelaou, Androniki, Muzny, Donna M., Nelson, Bradley J., Noor, Amina, Parrish, Nicholas F., Pendleton, Matthew, Quitadamo, Andrew, Raeder, Benjamin, Schadt, Eric E., Romanovitch, Mallory, Schlattl, Andreas, Sebra, Robert, Shabalin, Andrey A., Untergasser, Andreas, Walker, Jerilyn A., Wang, Min, Yu, Fuli, Zhang, Chengsheng, Zhang, Jing, Zheng-Bradley, Xiangqun, Zhou, Wanding, Zichner, Thomas, Sebat, Jonathan, Batzer, Mark A., McCarroll, Steven A., Mills, Ryan E., Gerstein, Mark B., Bashir, Ali, Stegle, Oliver, Devine, Scott E., Lee, Charles, Eichler, Evan E., Korbel, Jan O.

“…Structural variants are implicated in numerous diseases and make up the majority of varying nucleotides among human genomes. Here we describe an integrated set…”
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Cebidae Alu Element Alignments and a Complex Non-Human Primate Radiation by Storer, Jessica M, Walker, Jerilyn A, Brown, Morgan A, Batzer, Mark A

“…Phylogenetic relationships among Cebidae species of platyrrhine primates are presently under debate. Studies prior to whole genome sequence (WGS) availability…”
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Human Population Genetic Structure and Inference of Group Membership by Bamshad, Michael J., Wooding, Stephen, Watkins, W. Scott, Ostler, Christopher T., Batzer, Mark A., Jorde, Lynn B.

“…A major goal of biomedical research is to develop the capability to provide highly personalized health care. To do so, it is necessary to understand the…”
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Evolutionary dynamics of transposable elements in the short-tailed opossum Monodelphis domestica by Gentles, Andrew J, Wakefield, Matthew J, Kohany, Oleksiy, Gu, Wanjun, Batzer, Mark A, Pollock, David D, Jurka, Jerzy

“…The genome of the gray short-tailed opossum Monodelphis domestica is notable for its large size ( approximately 3.6 Gb). We characterized nearly 500 families…”
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Nuclear versus mitochondrial DNA: evidence for hybridization in colobine monkeys by Roos, Christian, Zinner, Dietmar, Kubatko, Laura S, Schwarz, Christiane, Yang, Mouyu, Meyer, Dirk, Nash, Stephen D, Xing, Jinchuan, Batzer, Mark A, Brameier, Markus, Leendertz, Fabian H, Ziegler, Thomas, Perwitasari-Farajallah, Dyah, Nadler, Tilo, Walter, Lutz, Osterholz, Martin

“…Colobine monkeys constitute a diverse group of primates with major radiations in Africa and Asia. However, phylogenetic relationships among genera are under…”
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Rates and patterns of great ape retrotransposition by Hormozdiari, Fereydoun, Konkel, Miriam K., Prado-Martinez, Javier, Chiatante, Giorgia, Herraez, Irene Hernando, Walker, Jerilyn A., Nelson, Benjamin, Alkan, Can, Sudmant, Peter H., Huddleston, John, Catacchio, Claudia R., Ko, Arthur, Malig, Maika, Baker, Carl, Marques-Bonet, Tomas, Ventura, Mario, Batzer, Mark A., Eichler, Evan E.

“…We analyzed 83 fully sequenced great ape genomes for mobile element insertions, predicting a total of 49,452 fixed and polymorphic Alu and long interspersed…”
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