Search Results - "Batty, T."
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Artemisinin combination therapy at delivery to prevent postpartum malaria: A randomised open-label controlled trial
Published in International journal of infectious diseases (01-12-2024)“…•First evaluation of ACT at delivery for prevention of malaria during postpartum.•Those receiving ACT were significantly less likely to develop slide-positive…”
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Development of a pharmaceutical science systematic review process using a semi‐automated machine learning tool: Intravenous drug compatibility in the neonatal intensive care setting
Published in Pharmacology research & perspectives (01-02-2024)“…Our objective was to establish and test a machine learning‐based screening process that would be applicable to systematic reviews in pharmaceutical sciences…”
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Short-course, high-dose primaquine regimens for the treatment of liver-stage vivax malaria in children
Published in International journal of infectious diseases (01-09-2023)“…•A novel 3.5-day primaquine (PQ) regimen was well tolerated and relatively safe.•Supervised doses given with food ameliorated the gastrointestinal adverse…”
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Ultra-short course, high-dose primaquine to prevent Plasmodium vivax infection following uncomplicated pediatric malaria: A randomized, open-label, non-inferiority trial of early versus delayed treatment
Published in International journal of infectious diseases (01-05-2023)“…•An ultra-short course (3.5 days) high-dose primaquine (PQ) regimen is safe and tolerable.•PQ has moderate efficacy in preventing the appearance of Plasmodium…”
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5
Stability of benzylpenicillin for continuous intravenous infusions: An isotonic formulation for therapeutic use and a low-dose formulation for clinical trial
Published in Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy (01-09-2022)“…The objectives of this study were to develop a stability-indicating high performance liquid chromatography (HPLC) assay for benzylpenicillin (BPC) in…”
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Physicochemical compatibility of pentoxifylline injection with high‐concentration parenteral medications
Published in Pediatric investigation (01-12-2023)“…An established procedure, including a validated, stability-indicating high-performance liquid chromatography (HPLC) assay was used for evaluating the physical…”
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The Physicochemical Compatibility of Sildenafil Injection with Parenteral Medications Used in Neonatal Intensive Care Settings
Published in Pharmaceutics (01-03-2024)“…Sildenafil is used to treat pulmonary hypertension in neonatal intensive care unit (NICU) settings. As multiple intravenous (IV) medications are…”
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High risk of early sub-therapeutic penicillin concentrations after intramuscular benzathine penicillin G injections in Ethiopian children and adults with rheumatic heart disease
Published in PLoS neglected tropical diseases (01-06-2021)“…Introduction Intramuscular benzathine penicillin G (BPG) injections are a cornerstone of secondary prophylaxis to prevent acute rheumatic fever (ARF) and…”
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Pharmacokinetics, Pharmacodynamics, and Allometric Scaling of Chloroquine in a Murine Malaria Model
Published in Antimicrobial Agents and Chemotherapy (01-08-2011)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Stabilization of resveratrol in blood circulation by conjugation to mPEG and mPEG-PLA polymers: investigation of conjugate linker and polymer composition on stability, metabolism, antioxidant activity and pharmacokinetic profile
Published in PloS one (23-03-2015)“…Resveratrol is naturally occurring phytochemical with diverse biological activities such as chemoprevention, anti-inflammatory, anti-cancer, anti-oxidant. But…”
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Synthesis and antimalarial evaluation of novel isocryptolepine derivatives
Published in Bioorganic & medicinal chemistry (15-12-2011)“…A novel series of mono- and di-substituted analogues of isocryptolepine have been synthesized and evaluated for in vitro antimalarial activity and…”
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The Artemiside-Artemisox-Artemisone-M1 Tetrad: Efficacies against Blood Stage P. falciparum Parasites, DMPK Properties, and the Case for Artemiside
Published in Pharmaceutics (03-12-2021)“…Because of the need to replace the current clinical artemisinins in artemisinin combination therapies, we are evaluating fitness of amino-artemisinins for this…”
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The effect of sickle cell genotype on the pharmacokinetic properties of artemether-lumefantrine in Tanzanian children
Published in International journal for parasitology -- drugs and drug resistance (01-08-2022)“…Since there are inconsistent data relating to the effect of haemoglobinopathies on disposition of artemisinin antimalarial combination therapy, and none in…”
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14
Predicting the parasite killing effect of artemisinin combination therapy in a murine malaria model
Published in Journal of antimicrobial chemotherapy (01-08-2014)“…To develop a mechanism-based model that describes the time course of the malaria parasite in infected mice receiving a combination therapy regimen of…”
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Pharmacokinetic Properties of Single-Dose Primaquine in Papua New Guinean Children: Feasibility of Abbreviated High-Dose Regimens for Radical Cure of Vivax Malaria
Published in Antimicrobial Agents and Chemotherapy (01-01-2014)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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16
Artemisinin-Naphthoquine Combination Therapy for Uncomplicated Pediatric Malaria: a Pharmacokinetic Study
Published in Antimicrobial Agents and Chemotherapy (01-05-2012)“…Artemisinin-naphthoquine (ART-NQ) is a coformulated antimalarial therapy marketed as a single-dose treatment in Papua New Guinea and other tropical countries…”
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Mechanism-Based Model of Parasite Growth and Dihydroartemisinin Pharmacodynamics in Murine Malaria
Published in Antimicrobial Agents and Chemotherapy (01-01-2013)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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18
Comparison of the sensitivity of conventional cytology and the ThinPrep Imaging System for 1,083 biopsy confirmed high-grade squamous lesions
Published in Diagnostic cytopathology (01-05-2010)“…Liquid‐based cytology continues to be utilized as an adjunct to conventional cytology in most Australian laboratories, even though a direct‐to‐vial ThinPrep…”
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Pharmacokinetics and Efficacy of Piperaquine and Chloroquine in Melanesian Children with Uncomplicated Malaria
Published in Antimicrobial Agents and Chemotherapy (01-01-2008)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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20
Effect of coadministered fat on the tolerability, safety, and pharmacokinetic properties of dihydroartemisinin-piperaquine in Papua New Guinean children with uncomplicated malaria
Published in Antimicrobial agents and chemotherapy (01-10-2014)“…Coadministration of dihydroartemisinin-piperaquine (DHA-PQ) with fat may improve bioavailability and antimalarial efficacy, but it might also increase…”
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