Search Results - "Batty, Elizabeth"

Long-read whole genome sequencing and comparative analysis of six strains of the human pathogen Orientia tsutsugamushi by Batty, Elizabeth M, Chaemchuen, Suwittra, Blacksell, Stuart, Richards, Allen L, Paris, Daniel, Bowden, Rory, Chan, Caroline, Lachumanan, Ramkumar, Day, Nicholas, Donnelly, Peter, Chen, Swaine, Salje, Jeanne

“…Orientia tsutsugamushi is a clinically important but neglected obligate intracellular bacterial pathogen of the Rickettsiaceae family that causes the…”
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Within-host evolution of Staphylococcus aureus during asymptomatic carriage by Golubchik, Tanya, Batty, Elizabeth M, Miller, Ruth R, Farr, Helen, Young, Bernadette C, Larner-Svensson, Hanna, Fung, Rowena, Godwin, Heather, Knox, Kyle, Votintseva, Antonina, Everitt, Richard G, Street, Teresa, Cule, Madeleine, Ip, Camilla L C, Didelot, Xavier, Peto, Timothy E A, Harding, Rosalind M, Wilson, Daniel J, Crook, Derrick W, Bowden, Rory

“…Staphylococcus aureus is a major cause of healthcare associated mortality, but like many important bacterial pathogens, it is a common constituent of the…”
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Evolutionary History of the Global Emergence of the Escherichia coli Epidemic Clone ST131 by Stoesser, Nicole, Sheppard, Anna E, Pankhurst, Louise, De Maio, Nicola, Moore, Catrin E, Sebra, Robert, Turner, Paul, Anson, Luke W, Kasarskis, Andrew, Batty, Elizabeth M, Kos, Veronica, Wilson, Daniel J, Phetsouvanh, Rattanaphone, Wyllie, David, Sokurenko, Evgeni, Manges, Amee R, Johnson, Timothy J, Price, Lance B, Peto, Timothy E A, Johnson, James R, Didelot, Xavier, Walker, A Sarah, Crook, Derrick W

“…Escherichia colisequence type 131 (ST131) has emerged globally as the most predominant extraintestinal pathogenic lineage within this clinically important…”
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Diverse Sources of C. difficile Infection Identified on Whole-Genome Sequencing by Eyre, David W, Cule, Madeleine L, Wilson, Daniel J, Griffiths, David, Vaughan, Alison, O'Connor, Lily, Ip, Camilla L.C, Golubchik, Tanya, Batty, Elizabeth M, Finney, John M, Wyllie, David H, Didelot, Xavier, Piazza, Paolo, Bowden, Rory, Dingle, Kate E, Harding, Rosalind M, Crook, Derrick W, Wilcox, Mark H, Peto, Tim E.A, Walker, A. Sarah

“…Where does Clostridium difficile come from? In this report from the United Kingdom, of 1223 C. difficile isolates that were evaluated on whole-genome…”
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Detection of maternal transmission of resistant Gram-negative bacteria in a Cambodian hospital setting by Chomkatekaew, Chalita, Thaipadungpanit, Janjira, Hearn, Pasco, Soeng, Sona, Pol, Sreymom, Neou, Leakhena, Hopkins, Jill, Turner, Paul, Batty, Elizabeth M

“…Infection with Extended-spectrum beta-lactamase -producing (ESBL-E) is common in infants and leads to increased intensive care unit admission and mortality,…”
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Evolutionary dynamics of Staphylococcus aureus during progression from carriage to disease by Young, Bernadette C, Golubchik, Tanya, Batty, Elizabeth M, Fung, Rowena, Larner-Svensson, Hanna, Votintseva, Antonina A, Miller, Ruth R, Godwin, Heather, Knox, Kyle, Everitt, Richard G, Iqbal, Zamin, Rimmer, Andrew J, Cule, Madeleine, Ip, Camilla L. C, Didelot, Xavier, Harding, Rosalind M, Donnelly, Peter, Peto, Tim E, Crook, Derrick W, Bowden, Rory, Wilson, Daniel J

“…Whole-genome sequencing offers new insights into the evolution of bacterial pathogens and the etiology of bacterial disease. Staphylococcus aureus is a major…”
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Genetic diversity, determinants, and dissemination of Burkholderia pseudomallei lineages implicated in melioidosis in Northeast Thailand by Seng, Rathanin, Chomkatekaew, Chalita, Tandhavanant, Sarunporn, Saiprom, Natnaree, Phunpang, Rungnapa, Thaipadungpanit, Janjira, Batty, Elizabeth M., Day, Nicholas P. J., Chantratita, Wasun, West, T. Eoin, Thomson, Nicholas R., Parkhill, Julian, Chewapreecha, Claire, Chantratita, Narisara

“…Melioidosis is an often-fatal neglected tropical disease caused by an environmental bacterium Burkholderia pseudomallei . However, our understanding of the…”
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Melioidosis in Patients with COVID-19 Exposed to Contaminated Tap Water, Thailand, 2021 by Tantirat, Panupong, Chantarawichian, Yotsathon, Taweewigyakarn, Pantila, Kripattanapong, Somkid, Jitpeera, Charuttaporn, Doungngern, Pawinee, Phiancharoen, Chadaporn, Tangwangvivat, Ratanaporn, Hinjoy, Soawapak, Sujariyakul, Anupong, Amornchai, Premjit, Wongsuvan, Gumphol, Hantakun, Viriya, Wuthiekanun, Vanaporn, Thaipadungpanit, Janjira, Thomson, Nicholas R, Dance, David A B, Chewapreecha, Claire, Batty, Elizabeth M, Limmathurotsakul, Direk

“…In September 2021, a total of 25 patients diagnosed with COVID-19 developed acute melioidosis after (median 7 days) admission to a COVID-19 field hospital in…”
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Oxford Nanopore MinION Sequencing Enables Rapid Whole Genome Assembly of Rickettsia typhi in a Resource-Limited Setting by Elliott, Ivo, Batty, Elizabeth M, Ming, Damien, Robinson, Matthew T, Nawtaisong, Pruksa, de Cesare, Mariateresa, Newton, Paul N, Bowden, Rory

“…The infrastructure challenges and costs of next-generation sequencing have been largely overcome, for many sequencing applications, by Oxford Nanopore…”
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Mobile elements drive recombination hotspots in the core genome of Staphylococcus aureus by Everitt, Richard G., Didelot, Xavier, Batty, Elizabeth M., Miller, Ruth R, Knox, Kyle, Young, Bernadette C., Bowden, Rory, Auton, Adam, Votintseva, Antonina, Larner-Svensson, Hanna, Charlesworth, Jane, Golubchik, Tanya, Ip, Camilla L. C., Godwin, Heather, Fung, Rowena, Peto, Tim E. A., Walker, A. Sarah, Crook, Derrick W., Wilson, Daniel J.

“…Horizontal gene transfer is an important driver of bacterial evolution, but genetic exchange in the core genome of clonal species, including the major pathogen…”
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Comparative analysis of targeted next-generation sequencing for Plasmodium falciparum drug resistance markers by Kunasol, Chanon, Dondorp, Arjen M., Batty, Elizabeth M., Nakhonsri, Vorthunju, Sinjanakhom, Puritat, Day, Nicholas P. J., Imwong, Mallika

“…Well-defined molecular resistance markers are available for a range of antimalarial drugs, and molecular surveillance is increasingly important for monitoring…”
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COVID-19 Transmission among Healthcare Workers at a Quarantine Facility in Thailand: Genomic and Outbreak Investigations by Atsawawaranunt, Kamolthip, Kochakarn, Theerarat, Kongklieng, Amornmas, Panwijitkul, Pakkaporn, Tragoolpua, Rujira, Jaradilokkul, Kanyarat, Kaewmalang, Prayuth, Loesbanluechai, Duangkamon, Kotanan, Namfon, Joonlasak, Khajohn, Batty, Elizabeth M, Mungaomklang, Anek, Pawun, Vichan, Chantratita, Wasun, Chookajorn, Thanat

“…During the COVID-19 pandemic, Thailand implemented a quarantine program at approved quarantine facilities for every international traveler. Here, we report an…”
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Genomic surveillance of SARS-CoV-2 in Thailand reveals mixed imported populations, a local lineage expansion and a virus with truncated ORF7a by Joonlasak, Khajohn, Batty, Elizabeth M, Kochakarn, Theerarat, Panthan, Bhakbhoom, Kümpornsin, Krittikorn, Jiaranai, Poramate, Wangwiwatsin, Arporn, Huang, Angkana, Kotanan, Namfon, Jaru-Ampornpan, Peera, Manasatienkij, Wudtichai, Watthanachockchai, Treewat, Rakmanee, Kingkan, Jones, Anthony R., Fernandez, Stefan, Sensorn, Insee, Sungkanuparph, Somnuek, Pasomsub, Ekawat, Klungthong, Chonticha, Chookajorn, Thanat, Chantratita, Wasun

“…•There were multiple introduction events of SARS-CoV-2 into Thailand.•One lineage, designated A/Thai-1, has expanded and has become a predominant and unique…”
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Improved workflows for high throughput library preparation using the transposome-based Nextera system by Lamble, Sarah, Batty, Elizabeth, Attar, Moustafa, Buck, David, Bowden, Rory, Lunter, Gerton, Crook, Derrick, El-Fahmawi, Bassam, Piazza, Paolo

“…The Nextera protocol, which utilises a transposome based approach to create libraries for Illumina sequencing, requires pure DNA template, an accurate…”
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Diversity of Human Enterovirus Co-Circulations in Five Kindergartens in Bangkok between July 2019 and January 2020 by Sittikul, Pichamon, Batty, Elizabeth M, Yodsawat, Prasert, Nuanpirom, Jiratchaya, Kosoltanapiwat, Nathamon, Sangket, Unitsa, Chatchen, Supawat, Day, Nicholas P J, Thaipadungpanit, Janjira

“…Human enterovirus causes various clinical manifestations in the form of rashes, febrile illness, flu-like illness, uveitis, hand-foot-mouth disease (HFMD),…”
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Phenotypic and genetic alterations of Burkholderia pseudomallei in patients during relapse and persistent infections by Seng, Rathanin, Phunpang, Rungnapa, Saiprom, Natnaree, Dulsuk, Adul, Chewapreecha, Claire, Thaipadungpanit, Janjira, Batty, Elizabeth M, Chantratita, Wasun, West, T Eoin, Chantratita, Narisara

“…The bacterium is the causative agent of melioidosis, a severe tropical disease associated with high mortality and relapse and persistent infections. Treatment…”
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Insights into Platypus Population Structure and History from Whole-Genome Sequencing by Martin, Hilary C, Batty, Elizabeth M, Hussin, Julie, Westall, Portia, Daish, Tasman, Kolomyjec, Stephen, Piazza, Paolo, Bowden, Rory, Hawkins, Margaret, Grant, Tom, Moritz, Craig, Grutzner, Frank, Gongora, Jaime, Donnelly, Peter

“…The platypus is an egg-laying mammal which, alongside the echidna, occupies a unique place in the mammalian phylogenetic tree. Despite widespread interest in…”
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MinION Analysis and Reference Consortium: Phase 1 data release and analysis by Ip, Camilla L C, Loose, Matthew, Tyson, John R, de Cesare, Mariateresa, Brown, Bonnie L, Jain, Miten, Leggett, Richard M, Eccles, David A, Zalunin, Vadim, Urban, John M, Piazza, Paolo, Bowden, Rory J, Paten, Benedict, Mwaigwisya, Solomon, Batty, Elizabeth M, Simpson, Jared T, Snutch, Terrance P, Birney, Ewan, Buck, David, Goodwin, Sara, Jansen, Hans J, O'Grady, Justin, Olsen, Hugh E

“…The advent of a miniaturized DNA sequencing device with a high-throughput contextual sequencing capability embodies the next generation of large scale…”
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Clinical Antiviral Efficacy of Remdesivir in Coronavirus Disease 2019: An Open-Label, Randomized Controlled Adaptive Platform Trial (PLATCOV) by Jittamala, Podjanee, Schilling, William H K, Watson, James A, Luvira, Viravarn, Siripoon, Tanaya, Ngamprasertchai, Thundon, Almeida, Pedro J, Ekkapongpisit, Maneerat, Cruz, Cintia, Callery, James J, Boyd, Simon, Anunsittichai, Orawan, Hongsuwan, Maliwan, Singhaboot, Yutatirat, Pagornrat, Watcharee, Tuntipaiboontana, Runch, Kruabkontho, Varaporn, Ngernseng, Thatsanun, Tubprasert, Jaruwan, Abdad, Mohammad Yazid, Keayarsa, Srisuda, Madmanee, Wanassanan, Aguiar, Renato S, Santos, Franciele M, Batty, Elizabeth M, Hanboonkunupakarn, Pongtorn, Hanboonkunupakarn, Borimas, Sookprome, Sakol, Poovorawan, Kittiyod, Imwong, Mallika, Taylor, Walter R J, Chotivanich, Vasin, Sangketchon, Chunlanee, Ruksakul, Wiroj, Chotivanich, Kesinee, Pukrittayakamee, Sasithon, Dondorp, Arjen M, Day, Nicholas P J, Teixeira, Mauro M, Piyaphanee, Watcharapong, Phumratanaprapin, Weerapong, White, Nicholas J

“…Abstract Background Uncertainty over the therapeutic benefit of parenteral remdesivir in coronavirus disease 2019 (COVID-19) has resulted in varying treatment…”
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A modified RNA-Seq approach for whole genome sequencing of RNA viruses from faecal and blood samples by Batty, Elizabeth M, Wong, T H Nicholas, Trebes, Amy, Argoud, Karène, Attar, Moustafa, Buck, David, Ip, Camilla L C, Golubchik, Tanya, Cule, Madeleine, Bowden, Rory, Manganis, Charis, Klenerman, Paul, Barnes, Eleanor, Walker, A Sarah, Wyllie, David H, Wilson, Daniel J, Dingle, Kate E, Peto, Tim E A, Crook, Derrick W, Piazza, Paolo

“…To date, very large scale sequencing of many clinically important RNA viruses has been complicated by their high population molecular variation, which creates…”
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