Search Results - "Battuello, Paolo"
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Integrated approaches for precision oncology in colorectal cancer: The more you know, the better
Published in Seminars in cancer biology (01-09-2022)“…Colorectal cancer (CRC) is one of the most common human malignancies accounting for approximately 10 % of worldwide cancer incidence and mortality. While…”
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DNA demethylation triggers cell free DNA release in colorectal cancer cells
Published in Genome medicine (09-10-2024)“…Liquid biopsy based on cell-free DNA (cfDNA) analysis holds significant promise as a minimally invasive approach for the diagnosis, genotyping, and monitoring…”
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Temozolomide Treatment Alters Mismatch Repair and Boosts Mutational Burden in Tumor and Blood of Colorectal Cancer Patients
Published in Cancer discovery (06-07-2022)“…The majority of metastatic colorectal cancers (mCRC) are mismatch repair (MMR) proficient and unresponsive to immunotherapy, whereas MMR-deficient (MMRd)…”
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Mutational signatures of colorectal cancers according to distinct computational workflows
Published in Briefings in bioinformatics (23-05-2024)“…Abstract Tumor mutational signatures have gained prominence in cancer research, yet the lack of standardized methods hinders reproducibility and robustness…”
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Abstract 5284: Immune surveillance of chemotherapy-induced mutant subclones in CRC
Published in Cancer research (Chicago, Ill.) (22-03-2024)“…Abstract Molecular alterations generated by DNA repair deficiencies and DNA damaging agents can be detected by the host immune system and this can restrict…”
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Abstract 6262: Emergence of tumor mismatch repair deficiency and increased mutational burden in blood and tissue of metastatic colorectal cancer patients treated with temozolomide
Published in Cancer research (Chicago, Ill.) (15-06-2022)“…Abstract The majority of metastatic colorectal cancers (mCRC) are mismatch repair (MMR) proficient (MMRp) and unresponsive to immunotherapy, while MMR…”
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