Search Results - "Battig, Mark"

Programmable Release of Multiple Protein Drugs from Aptamer-Functionalized Hydrogels via Nucleic Acid Hybridization by Battig, Mark R, Soontornworajit, Boonchoy, Wang, Yong

“…Polymeric delivery systems have been extensively studied to achieve localized and controlled release of protein drugs. However, it is still challenging to…”
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Programmable Hydrogels for Controlled Cell Catch and Release Using Hybridized Aptamers and Complementary Sequences by Zhang, Zhaoyang, Chen, Niancao, Li, Shihui, Battig, Mark R, Wang, Yong

“…The ability to regulate cell–material interactions is important in various applications such as regenerative medicine and cell separation. This study…”
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Aptamer-based molecular recognition for biosensor development by Zhou, Jing, Battig, Mark R, Wang, Yong

“…Nucleic acid aptamers are an emerging class of synthetic ligands and have recently attracted significant attention in numerous fields. One is in biosensor…”
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Treatment of severe Kaposiform lymphangiomatosis positive for NRAS mutation by MEK inhibition by Chowers, Guy, Abebe-Campino, Gadi, Golan, Hana, Vivante, Asaf, Greenberger, Shoshana, Soudack, Michalle, Barkai, Galia, Fox-Fisher, Ilana, Li, Dong, March, Michael, Battig, Mark R., Hakonarson, Hakon, Adams, Denise, Dori, Yoav, Dagan, Adi

“…Background Kaposiform lymphangiomatosis (KLA) is a complex lymphatic anomaly involving most commonly the mediastinum, lung, skin and bones with few effective…”
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Aptamer-functionalized superporous hydrogels for sequestration and release of growth factors regulated via molecular recognition by Battig, Mark R, Huang, Yike, Chen, Niancao, Wang, Yong

“…Abstract While the discovery of highly potent biologics has led to the development of promising therapies for various human diseases, biologics can cause…”
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ARAF recurrent mutation causes central conducting lymphatic anomaly treatable with a MEK inhibitor by Li, Dong, March, Michael E., Gutierrez-Uzquiza, Alvaro, Kao, Charlly, Seiler, Christoph, Pinto, Erin, Matsuoka, Leticia S., Battig, Mark R., Bhoj, Elizabeth J., Wenger, Tara L., Tian, Lifeng, Robinson, Nora, Wang, Tiancheng, Liu, Yichuan, Weinstein, Brant M., Swift, Matthew, Jung, Hyun Min, Kaminski, Courtney N., Chiavacci, Rosetta, Perkins, Jonathan A., Levine, Michael A., Sleiman, Patrick M. A., Hicks, Patricia J., Strausbaugh, Janet T., Belasco, Jean B., Dori, Yoav, Hakonarson, Hakon

“…The treatment of lymphatic anomaly, a rare devastating disease spectrum of mostly unknown etiologies, depends on the patient manifestations 1 . Identifying the…”
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Chimeric Aptamer–Gelatin Hydrogels as an Extracellular Matrix Mimic for Loading Cells and Growth Factors by Zhang, Xiaolong, Battig, Mark R., Chen, Niancao, Gaddes, Erin R., Duncan, Katelyn L., Wang, Yong

“…It is important to synthesize materials to recapitulate critical functions of biological systems for a variety of applications such as tissue engineering and…”
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Insights Image for “Treatment of severe Kaposiform Lymphangiomatosis positive for NRAS mutation by MEK-inhibition” by Chowers, Guy, Abebe-Campino, Gadi, Golan, Hana, Vivante, Asaf, Greenberger, Shoshana, Soudack, Michalle, Barkai, Galia, Fox-Fisher, Ilana, Li, Dong, March, Michael, Battig, Mark R., Hakonarson, Hakon, Adams, Denise, Dori, Yoav, Dagan, Adi

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Development of a Dual‐Functional Hydrogel Using RGD and Anti‐VEGF Aptamer by Zhao, Nan, Battig, Mark R., Xu, Ming, Wang, Xiuli, Xiong, Na, Wang, Yong

“…Synthetic molecular libraries hold great potential to advance the biomaterial development. However, little effort is made to integrate molecules with molecular…”
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Affinity hydrogels for controlled protein release using nucleic acid aptamers and complementary oligonucleotides by Soontornworajit, Boonchoy, Zhou, Jing, Snipes, Matthew P, Battig, Mark R, Wang, Yong

“…Abstract Biomaterials for the precise control of protein release are important to the development of new strategies for treating human diseases. This study…”
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Programmable hydrogels for the controlled release of therapeutic nucleic acid aptamers via reversible DNA hybridization by Zhang, Xiaolong, Battig, Mark R, Wang, Yong

“…Reversible DNA hybridization can be used as a new mechanism to control the sustained and triggered release of therapeutic oligonucleotides from hydrogels…”
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Novel insights into the phenotypic spectrum and pathogenesis of Hardikar syndrome by Strong, Alanna, March, Michael E., Cardinale, Christopher J., Liu, Yichuan, Battig, Mark R., Finoti, Livia Sertori, Matsuoka, Leticia S., Watson, Deborah, Sridhar, Sindura, Jarrett, James F., Cannon, India, Li, Dong, Bhoj, Elizabeth, Zackai, Elaine H., Rand, Elizabeth B., Wenger, Tara, Lerman, Bruce B., Shikany, Amy, Weaver, K. Nicole, Hakonarson, Hakon

“…Hardikar syndrome (HS, MIM #301068) is a female-specific multiple congenital anomaly syndrome characterized by retinopathy, orofacial clefting, aortic…”
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Polymerization of Affinity Ligands on a Surface for Enhanced Ligand Display and Cell Binding by Richards, Erin, Li, Shihui, Chen, Niancao, Battig, Mark R, Wang, Yong

“…Surfaces functionalized with affinity ligands have been widely studied for applications such as biological separations and cell regulation. While individual…”
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Programmable Imaging Amplification via Nanoparticle-Initiated DNA Polymerization by Chen, Niancao, Li, Shihui, Battig, Mark R., Wang, Yong

“…DNA growth on nanoparticles: Nanoparticle‐mediated molecular recognition and DNA polymerization are integrated for extracellular matrix (ECM) imaging via…”
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Lymphatic disorders caused by mosaic, activating KRAS variants respond to MEK inhibition by Sheppard, Sarah E, March, Michael E, Seiler, Christoph, Matsuoka, Leticia S, Kim, Sophia E, Kao, Charlly, Rubin, Adam I, Battig, Mark R, Khalek, Nahla, Schindewolf, Erica, O'Connor, Nora, Pinto, Erin, Priestley, Jessica Rc, Sanders, Victoria R, Niazi, Rojeen, Ganguly, Arupa, Hou, Cuiping, Slater, Diana, Frieden, Ilona J, Huynh, Thy, Shieh, Joseph T, Krantz, Ian D, Guerrero, Jessenia C, Surrey, Lea F, Biko, David M, Laje, Pablo, Castelo-Soccio, Leslie, Nakano, Taizo A, Snyder, Kristen, Smith, Christopher L, Li, Dong, Dori, Yoav, Hakonarson, Hakon

“…Central conducting lymphatic anomaly (CCLA) due to congenital maldevelopment of the lymphatics can result in debilitating and life-threatening disease with…”
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O27: Utility of cfDNA in comprehensive genomic profiling of complex vascular anomalies: Informing decision making in medical therapy by Li, Dong, Sheppard, Sarah, March, Michael, Battig, Mark, Surrey, Lea, Srinivasan, Abhay, Borst, Alexandra, Wang, Fengxiang, Sikder, Tamjeed, O’Connor, Nora, Thomas, Alexandria, Pinto, Erin, Britt, Allison, Napoli, Joseph, Low, David, Vatsky, Seth, Treat, James, Reid, Janet, Smith, Christopher, Snyder, Kristen, Cahill, Anne Marie, Dori, Yoav, Adams, Denise, Hakonarson, Hakon

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Optimizing endothelial cell functionalization for cell therapy of vascular proliferative disease using a direct contact co-culture system by Battig, Mark R., Fishbein, Ilia, Levy, Robert J., Alferiev, Ivan S., Guerrero, David, Chorny, Michael

“…Increased susceptibility to thrombosis, neoatherosclerosis, and restenosis due to incomplete regrowth of the protective endothelial layer remains a critical…”
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Genomic profiling informs diagnoses and treatment in vascular anomalies by Li, Dong, Sheppard, Sarah E., March, Michael E., Battig, Mark R., Surrey, Lea F., Srinivasan, Abhay S., Matsuoka, Leticia S., Tian, Lifeng, Wang, Fengxiang, Seiler, Christoph, Dayneka, Jill, Borst, Alexandra J., Matos, Mary C., Paulissen, Scott M., Krishnamurthy, Ganesh, Nriagu, Bede, Sikder, Tamjeed, Casey, Melissa, Williams, Lydia, Rangu, Sneha, O’Connor, Nora, Thomas, Alexandria, Pinto, Erin, Hou, Cuiping, Nguyen, Kenny, Pellegrino da Silva, Renata, Chehimi, Samar N., Kao, Charlly, Biroc, Lauren, Britt, Allison D., Queenan, Maria, Reid, Janet R., Napoli, Joseph A., Low, David M., Vatsky, Seth, Treat, James, Smith, Christopher L., Cahill, Anne Marie, Snyder, Kristen M., Adams, Denise M., Dori, Yoav, Hakonarson, Hakon

“…Vascular anomalies are malformations or tumors of the blood or lymphatic vasculature and can be life-threatening. Although molecularly targeted therapies can…”
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Experimental Single-Platform Approach to Enhance the Functionalization of Magnetically Targetable Cells by Battig, Mark R., Alferiev, Ivan S., Guerrero, David T., Fishbein, Ilia, Pressly, Benjamin B., Levy, Robert J., Chorny, Michael

“…Magnetic guidance shows promise as a strategy for improving the delivery and performance of cell therapeutics. However, clinical translation of magnetically…”
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Aptamer-based molecular recognition for biosensor development : Bioanalysis by JING ZHOU, BATTIG, Mark R, YONG WANG

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