Search Results - "Battella, Simone"

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    CD16 pre-ligation by defucosylated tumor-targeting mAb sensitizes human NK cells to γc cytokine stimulation via PI3K/mTOR axis by Capuano, Cristina, Pighi, Chiara, Maggio, Roberta, Battella, Simone, Morrone, Stefania, Palmieri, Gabriella, Santoni, Angela, Klein, Christian, Galandrini, Ricciarda

    Published in Cancer Immunology, Immunotherapy (01-04-2020)
    “…Obinutuzumab is a glycoengineered tumor-targeting anti-CD20 mAb with a modified crystallizable fragment (Fc) domain designed to increase the affinity for the…”
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    Journal Article
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    Memory NK Cell Features Exploitable in Anticancer Immunotherapy by Palmieri, Gabriella, Santoni, Angela, Battella, Simone, Pighi, Chiara, Capuano, Cristina, Galandrini, Ricciarda

    Published in Journal of immunology research (01-01-2019)
    “…Besides their innate ability to rapidly produce effector cytokines and kill virus-infected or transformed cells, natural killer (NK) cells display a strong…”
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    Journal Article
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    Obinutuzumab-mediated high-affinity ligation of FcγRIIIA/CD16 primes NK cells for IFNγ production by Capuano, Cristina, Pighi, Chiara, Molfetta, Rosa, Paolini, Rossella, Battella, Simone, Palmieri, Gabriella, Giannini, Giuseppe, Belardinilli, Francesca, Santoni, Angela, Galandrini, Ricciarda

    Published in Oncoimmunology (04-03-2017)
    “…Natural killer (NK) cell-mediated antibody-dependent cellular cytotoxicity (ADCC), based on the recognition of IgG-opsonized targets by the low-affinity…”
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    Journal Article
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    (Auto)Antibody Responses Shape Memory NK Cell Pool Size and Composition by Capuano, Cristina, Pighi, Chiara, Battella, Simone, Pulcinelli, Fabio, Santoro, Cristina, Ferretti, Antonietta, Turriziani, Ombretta, De Federicis, Davide, Fionda, Cinzia, Sciumè, Giuseppe, Galandrini, Ricciarda, Palmieri, Gabriella

    Published in Biomedicines (08-03-2022)
    “…In vivo establishment and long-term persistence of a heterogeneous memory or an adaptive NK cell pool represents a functional adaptation to human…”
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    Journal Article
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    Natural killer (NK) cells and anti‐tumor therapeutic mAb: unexplored interactions by Battella, Simone, Cox, Maria Christina, Santoni, Angela, Palmieri, Gabriella

    Published in Journal of leukocyte biology (01-01-2016)
    “…Review of interactions between NK cells and therapeutic tumor‐targeting mAbs, and development of novel NK cell‐based strategies for cancer treatment…”
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    Journal Article
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    Harnessing CD16-Mediated NK Cell Functions to Enhance Therapeutic Efficacy of Tumor-Targeting mAbs by Capuano, Cristina, Pighi, Chiara, Battella, Simone, De Federicis, Davide, Galandrini, Ricciarda, Palmieri, Gabriella

    Published in Cancers (20-05-2021)
    “…Natural killer (NK) cells hold a pivotal role in tumor-targeting monoclonal antibody (mAb)-based activity due to the expression of CD16, the low-affinity…”
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    Journal Article
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    Regulation and trafficking of the HLA‐E molecules during monocyte‐macrophage differentiation by Camilli, Giorgio, Cassotta, Antonino, Battella, Simone, Palmieri, Gabriella, Santoni, Angela, Paladini, Fabiana, Fiorillo, Maria Teresa, Sorrentino, Rosa

    Published in Journal of leukocyte biology (01-01-2016)
    “…HLA‐E molecules undergo an alternative pathway of intracellular trafficking in monocyte‐derived macrophages. HLA‐E is a nonclassical HLA‐class I molecule whose…”
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    Journal Article
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