Search Results - "Batsa Debrah, Linda"

Multimodal biomarker discovery for active Onchocerca volvulus infection by Lagatie, Ole, Njumbe Ediage, Emmanuel, Van Roosbroeck, Dirk, Van Asten, Stijn, Verheyen, Ann, Batsa Debrah, Linda, Debrah, Alex, Odiere, Maurice R, T'Kindt, Ruben, Dumont, Emmie, Sandra, Koen, Dillen, Lieve, Verhaeghe, Tom, Vreeken, Rob, Cuyckens, Filip, Stuyver, Lieven J

“…The neglected tropical disease onchocerciasis, or river blindness, is caused by infection with the filarial nematode Onchocerca volvulus. Current estimates…”
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Pathological manifestations in lymphatic filariasis correlate with lack of inhibitory properties of IgG4 antibodies on IgE-activated granulocytes by Prodjinotho, Ulrich F, von Horn, Charlotte, Debrah, Alex Y, Batsa Debrah, Linda, Albers, Anna, Layland, Laura E, Hoerauf, Achim, Adjobimey, Tomabu

“…Helminth parasites are known to be efficient modulators of their host's immune system. To guarantee their own survival, they induce alongside the classical Th2…”
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Whole blood transcriptome analysis in onchocerciasis by Lagatie, Ole, Batsa Debrah, Linda, Debrah, Alex Y., Stuyver, Lieven J.

“…Identifying the molecular mechanisms controlling the host’s response to infection with Onchocerca volvulus is important to understand how the human host…”
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BCG-Vaccinated Children with Contact to Tuberculosis Patients Show Delayed Conversion of Mycobacterium tuberculosis -Specific IFN-γ Release by Owusu, Dorcas O, Adankwah, Ernest, Aniagyei, Wilfred, Acheampong, Isaac, Minadzi, Difery, Yeboah, Augustine, Arthur, Joseph F, Lamptey, Millicent, Vivekanandan, Monika M, Abass, Mohammed K, Kumbel, Francis, Osei-Yeboah, Francis, Gawusu, Amidu, Batsa Debrah, Linda, Debrah, Alexander, Mayatepek, Ertan, Seyfarth, Julia, Phillips, Richard O, Jacobsen, Marc

“…BCG vaccination is recommended for healthy babies after birth in several countries with a high prevalence of tuberculosis, including Ghana. Previous studies…”
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Stage-Dependent Increase of Systemic Immune Activation and CCR5 + CD4 + T Cells in Filarial Driven Lymphedema in Ghana and Tanzania by Rahamani, Abu Abudu, Horn, Sacha, Ritter, Manuel, Feichtner, Anja, Osei-Mensah, Jubin, Serwaa Opoku, Vera, Batsa Debrah, Linda, Marandu, Thomas F, Haule, Antelmo, Mhidze, Jacklina, Ngenya, Abdallah, Demetrius, Max, Klarmann-Schulz, Ute, Hoelscher, Michael, Geldmacher, Christof, Hoerauf, Achim, Kalinga, Akili, Debrah, Alexander Y, Kroidl, Inge

“…Chronic lymphedema caused by infection of is a disfiguring disease that leads to physical disability, stigmatization, and reduced quality of life. The…”
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Plasma-derived parasitic microRNAs have insufficient concentrations to be used as diagnostic biomarker for detection of Onchocerca volvulus infection or treatment monitoring using LNA-based RT-qPCR by Lagatie, Ole, Batsa Debrah, Linda, Debrah, Alex, Stuyver, Lieven J.

“…River blindness, caused by infection with the filarial nematode Onchocerca volvulus , is a neglected tropical disease affecting millions of people. There is a…”
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Comparison of Repeated Doses of Ivermectin Versus Ivermectin Plus Albendazole for the Treatment of Onchocerciasis: A Randomized, Open-label, Clinical Trial by Batsa Debrah, Linda, Klarmann-Schulz, Ute, Osei-Mensah, Jubin, Dubben, Bettina, Fischer, Kerstin, Mubarik, Yusif, Ayisi-Boateng, Nana Kwame, Ricchiuto, Arcangelo, Fimmers, Rolf, Konadu, Peter, Nadal, Jennifer, Gruetzmacher, Barbara, Weil, Gary, Kazura, James W, King, Christopher L, Debrah, Alexander Y, Hoerauf, Achim

“…Abstract Background Improved treatment for onchocerciasis is needed to accelerate onchocerciasis elimination in Africa. Aiming to better exploit registered…”
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Lower IL-7 Receptor Expression of Monocytes Impairs Antimycobacterial Effector Functions in Patients with Tuberculosis by Adankwah, Ernest, Harelimana, Jean De Dieu, Minadzi, Difery, Aniagyei, Wilfred, Abass, Mohammed K, Batsa Debrah, Linda, Owusu, Dorcas O, Mayatepek, Ertan, Phillips, Richard O, Jacobsen, Marc

“…Altered monocyte differentiation and effector functions characterize immune pathogenesis of tuberculosis. IL-7 is an important factor for proliferation of T…”
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Doxycycline Treatment of Mansonella perstans–Infected Individuals Affects Immune Cell Activation and Causes Long-term T-cell Polarization by Aniagyei, Wilfred, Adjei, Jonathan Kofi, Adankwah, Ernest, Seyfarth, Julia, Mayatepek, Ertan, Antwi Berko, Daniel, Sakyi, Samuel Asamoah, Batsa Debrah, Linda, Debrah, Alexander Yaw, Hoerauf, Achim, Owusu, Dorcas O, Phillips, Richard O, Jacobsen, Marc

“…Abstract Background Doxycycline is used for treatment of Mansonella perstans infection. Immune modulatory effects of both M. perstans and doxycycline have been…”
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Evaluation of the Diagnostic Performance of Onchocerca volvulus Linear Epitopes in a Peptide Enzyme-Linked Immunosorbent Assay by Lagatie, Ole, Verheyen, Ann, Nijs, Erik, Van Dorst, Bieke, Batsa Debrah, Linda, Debrah, Alex, Supali, Taniawati, Sartono, Erliyani, Stuyver, Lieven J

“…Diagnostic tools for the detection of infection with are presently limited to microfilaria detection in skin biopsies and serological assessment using the Ov16…”
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Occurrence of Lymphatic Filariasis infection after 15 years of mass drug administration in two hotspot districts in the Upper East Region of Ghana by Adu Mensah, Derrick, Debrah, Linda Batsa, Gyamfi, Peter Akosah, Rahamani, Abu Abudu, Opoku, Vera Serwaa, Boateng, John, Obeng, Prince, Osei-Mensah, Jubin, Kroidl, Inge, Klarmann-Schulz, Ute, Hoerauf, Achim, Debrah, Alexander Yaw

“…BACKGROUNDLymphatic filariasis (LF) causes chronic morbidity, which usually manifests as lymphedema or hydrocele. Mass drug administration (MDA) began in…”
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Association of haemato-biochemical indices and blood composite ratios with microfilaridermia in Onchocerciasis patients by Debrah, Linda Batsa, Gyasi, Charles, Ahiadorme, Monica, Rahamani, Abu Abudu, Opoku, Vera Serwaa, Obeng, Prince, Osei-Mensah, Jubin, Obeng, Michael Agyemang, Mensah, Derrick Adu, Debrah, Alexander Yaw

“…Onchocerciasis causes chronic systemic inflammation. Several studies have used markers such as haemato-biochemical indices to predict the occurrence of…”
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Wuchereria bancrofti-infected individuals harbor distinct IL-10-producing regulatory B and T cell subsets which are affected by anti-filarial treatment by Ritter, Manuel, Osei-Mensah, Jubin, Debrah, Linda Batsa, Kwarteng, Alexander, Mubarik, Yusif, Debrah, Alexander Y, Pfarr, Kenneth, Hoerauf, Achim, Layland, Laura E

“…Despite worldwide mass drug administration, it is estimated that 68 million individuals are still infected with lymphatic filariasis with 19 million hydrocele…”
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The Efficacy of Doxycycline Treatment on Mansonella perstans Infection: An Open-Label, Randomized Trial in Ghana by Batsa Debrah, Linda, Phillips, Richard O, Pfarr, Kenneth, Klarmann-Schulz, Ute, Opoku, Vera Serwaa, Nausch, Norman, Owusu, Wellington, Mubarik, Yusif, Sander, Anna-Lena, Lämmer, Christine, Ritter, Manuel, Layland, Laura E, Jacobsen, Marc, Debrah, Alexander Yaw, Hoerauf, Achim

“…Treating is challenged by the low efficacy of registered antihelminthics. endobacteria provide an alternative treatment target because depletion results in…”
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Diminished Interleukin-7 receptor expression on T-cell subsets in tuberculosis patients by Acheampong, Isaac, Minadzi, Difery, Adankwah, Ernest, Aniagyei, Wilfred, Vivekanandan, Monika M., Yeboah, Augustine, Arthur, Joseph F., Lamptey, Millicent, Abass, Mohammed K., Kumbel, Francis, Osei-Yeboah, Francis, Gawusu, Amidu, Laing, Edwin F., Batsa Debrah, Linda, Owusu, Dorcas O., Debrah, Alexander, Mayatepek, Ertan, Seyfarth, Julia, Phillips, Richard O., Jacobsen, Marc

“…Immunopathology in human tuberculosis affects T-cell phenotype and functions. Previous studies identified impaired T-cell sensitivity to Interleukin (IL)-7…”
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Performance evaluation of 3 serodiagnostic peptide epitopes and the derived multi-epitope peptide OvNMP-48 for detection of Onchocerca volvulus infection by Lagatie, Ole, Verheyen, Ann, Nijs, Erik, Batsa Debrah, Linda, Debrah, Yaw A., Stuyver, Lieven J.

“…Current diagnostic tools to determine infection with the helminth parasite Onchocerca volvulus have limited performance characteristics. In previous studies, a…”
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Seroprevalence and Risk Factors of Toxoplasma gondii Infection among Pregnant Women in Kumasi: A Cross-Sectional Study at a District-Level Hospital, Ghana by Singh, Bhavana, Debrah, Linda Batsa, Acheampong, Godfred, Debrah, Alexander Yaw

“…Background. This study investigated the prevalence and risk factors of Toxoplasma gondii infection among pregnant women in a district-level hospital in Ghana…”
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Mhealth tools for community-based infectious disease surveillance in Africa: a scoping review protocol by Aku, Fortress Yayra, Amuasi, John Humphrey, Debrah, Linda Batsa, Opoku, Daniel, Gmanyami, Jonathan Mawutor, Hoerauf, Achim, Debrah, Alexander Yaw, Quentin, Wilm

“…IntroductionCountries in the WHO’s African region have found community-based surveillance useful in ensuring the effectiveness of the Integrated Disease…”
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Linear epitopes in Onchocerca volvulus vaccine candidate proteins and excretory‐secretory proteins by Lagatie, Ole, Verheyen, Ann, Van Dorst, Bieke, Batsa Debrah, Linda, Debrah, Alex, Stuyver, Lieven J.

“…Summary In our previous study, a proteome‐wide screen was conducted to identify linear epitopes in this parasite's proteome, resulting in the discovery of…”
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An isothermal DNA amplification method for detection of Onchocerca volvulus infection in skin biopsies by Lagatie, Ole, Merino, Michelle, Batsa Debrah, Linda, Debrah, Alexander Y, Stuyver, Lieven J

“…Diagnostic procedures for the diagnosis of infection with the nematode parasite Onchocerca volvulus are currently based on the microscopic detection of…”
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