Search Results - "Batista Teixeira Rocha, João"

Valeriana officinalis attenuates the rotenone-induced toxicity in Drosophila melanogaster by Sudati, Jéssie Haigert, Vieira, Francielli Araújo, Pavin, Sandra Sartoretto, Dias, Glaecir Roseni Mundstock, Seeger, Rodrigo Lopes, Golombieski, Ronaldo, Athayde, Margareth Linde, Soares, Félix Antunes, Rocha, João Batista Teixeira, Barbosa, Nilda Vargas

“…•VAL was effective against rotenone toxicity in D. melanogaster.•VAL protects flies from lethality and movement disorders caused by rotenone.•Protection of VAL…”
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Caffeine prevents disruption of memory consolidation in the inhibitory avoidance and novel object recognition tasks by scopolamine in adult mice by Botton, Paulo Henrique, Costa, Marcelo S., Ardais, Ana Paula, Mioranzza, Sabrina, Souza, Diogo O., da Rocha, João Batista Teixeira, Porciúncula, Lisiane O.

“…Caffeine is a psychostimulant with positive effects on cognition. Recent studies have suggested the participation of the cholinergic system in the effects of…”
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Acid sphingomyelinase (ASM) and COVID‐19: A review of the potential use of ASM inhibitors against SARS‐CoV‐2 by Pauletto, Pedro José Tronco, Delgado, Cassia Pereira, Rocha, João Batista Teixeira

“…In the last 2 years, different pharmacological agents have been indicated as potential inhibitors of SARS‐CoV‐2 in vitro. Specifically, drugs termed as…”
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In Silico Studies of Mammalian δ‐ALAD Interactions with Selenides and Selenoxides by Andrei Nogara, Pablo, Batista Teixeira Rocha, João

“…Previous studies have shown that the mammalian δ‐aminolevulinic acid dehydratase (δ‐ALAD) is inhibited by selenides and selenoxides, which can involve thiol…”
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Molecular Pathways Associated With Methylmercury-Induced Nrf2 Modulation by Unoki, Takamitsu, Akiyama, Masahiro, Kumagai, Yoshito, Gonçalves, Filipe Marques, Farina, Marcelo, da Rocha, João Batista Teixeira, Aschner, Michael

“…Methylmercury (MeHg) is a potent neurotoxin that affects particularly the developing brain. Since MeHg is a potent electrophilic agent, a wide range of…”
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Catuaba (Trichilia catigua) Prevents Against Oxidative Damage Induced by In Vitro Ischemia–Reperfusion in Rat Hippocampal Slices by Kamdem, Jean Paul, Waczuk, Emily Pansera, Kade, Ige Joseph, Wagner, Caroline, Boligon, Aline Augusti, Athayde, Margareth Linde, Souza, Diogo Onofre, Rocha, João Batista Teixeira

“…Oxidative stress is implicated in brain damage associated with ischemia–reperfusion. Natural antioxidants found in some plants used in folk medicine have been…”
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Oxidative stress-mediated inhibition of brain creatine kinase activity by methylmercury by Glaser, Viviane, Leipnitz, Guilhian, Straliotto, Marcos Raniel, Oliveira, Jade, dos Santos, Vanessa Valgas, Wannmacher, Clóvis Milton Duval, de Bem, Andreza Fabro, Rocha, João Batista Teixeira, Farina, Marcelo, Latini, Alexandra

“…Methylmercury (MeHg), a potent neurotoxicant, easily passes through the blood–brain barrier and accumulates in brain causing severe irreversible damage…”
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Diphenyl diselenide administration enhances cortical mitochondrial number and activity by increasing hemeoxygenase type 1 content in a methylmercury-induced neurotoxicity mouse model by Glaser, Viviane, Martins, Roberta de Paula, Vieira, Ana Julia Hoffmann, Oliveira, Eliana de Medeiros, Straliotto, Marcos Raniel, Mukdsi, Jorge Humberto, Torres, Alicia Inés, de Bem, Andreza Fabro, Farina, Marcelo, da Rocha, João Batista Teixeira, De Paul, Ana Lucia, Latini, Alexandra

“…Interest in biochemistry of organoselenium compound has increased in the last decades, mainly due to their chemical and biological activities. Here, we…”
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The Insecticidal Activity of Rhinella schneideri (Werner, 1894) Paratoid Secretion in Nauphoeta cinerea Cocroaches by Leal, Allan, Karnopp, Etiely, Barreto, Yuri Correia, Oliveira, Raquel Soares, Rosa, Maria Eduarda, Borges, Bruna Trindade, Goulart, Flávia Luana, Souza, Velci Queiróz de, Laikowski, Manuela Merlin, Moura, Sidnei, Vinadé, Lúcia, Rocha, João Batista Teixeira da, Dal Belo, Cháriston André

“…is a common toad found in South America, whose paratoid toxic secretion has never been explored as an insecticide. In order to evaluate its insecticidal…”
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Effect of Prepartum Maternal Supplementation with Diphenyl Diselenide on Biochemical, Immunological, and Oxidative Parameters of the Offspring by Rodrigues, Cláudia Medeiros, Parmeggiani, Eliana Burtet, Leal, Karoline Wagner, Schneider, Marla, Collet, Silvana Giacomini, Cibin, Francielli Weber Santos, Gomes, Viviani, Blagitz, Maiara Garcia, Rocha, João Batista Teixeira da, Leal, Marta Lizandra do Rêgo

“…This study aimed to assess the impact of prepartum maternal diphenyl diselenide (PhSe) supplementation on the development, biochemical, immune, and antioxidant…”
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Diphenyl Diselenide Prevents Cortico-cerebral Mitochondrial Dysfunction and Oxidative Stress Induced by Hypercholesterolemia in LDL Receptor Knockout Mice by de Oliveira, Jade, Moreira, Eduardo Luiz Gasnhar, Mancini, Gianni, Hort, Mariana Appel, Latini, Alexandra, Ribeiro-do-Valle, Rosa Maria, Farina, Marcelo, da Rocha, João Batista Teixeira, de Bem, Andreza Fabro

“…Recent studies have indicated a causal link between high dietary cholesterol intake and brain oxidative stress. In particular, we have previously shown a…”
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Methylmercury Can Facilitate the Formation of Dehydroalanine in Selenoenzymes: Insight from DFT Molecular Modeling by Nogara, Pablo Andrei, Madabeni, Andrea, Bortoli, Marco, Teixeira Rocha, João Batista, Orian, Laura

“…Experimental studies have indicated that electrophilic mercury forms (e.g., methylmercury, MeHg+) can accelerate the breakage of selenocysteine in vitro…”
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Synthesis and biological evaluation of 2-picolylamide-based diselenides with non-bonded interactions by Rafique, Jamal, Saba, Sumbal, Canto, Rômulo Faria Santos, Frizon, Tiago Elias Allievi, Hassan, Waseem, Waczuk, Emily Pansera, Jan, Maryam, Back, Davi Fernando, Da Rocha, João Batista Teixeira, Braga, Antonio Luiz

“…In this paper, we report the synthesis and biological evaluation of picolylamide-based diselenides with the aim of developing a new series of diselenides with…”
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(PhSe)2 and (pCl-PhSe)2 organochalcogen compounds inhibit Candida albicans adhesion to human endocervical (HeLa) cells and show anti-biofilm activities by da Silva, Bruna Marques, Braga, Marília Toledo, da Silva Passos, Juliene Cristina, Carvalho, Moisés Lopes, Rosseti, Isabela Bueno, de Amorim, Laís Mayara Machado, da Rocha, João Batista Teixeira, Alberto-Silva, Carlos, Costa, Maricilia Silva

“…Adhesion capacity on biological surfaces and biofilm formation is considered an important step in the infection process by Candida albicans. The ability of…”
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In silico Studies on the Interaction between Mpro and PLpro From SARS‐CoV‐2 and Ebselen, its Metabolites and Derivatives by Nogara, Pablo Andrei, Omage, Folorunsho Bright, Bolzan, Gustavo Roni, Delgado, Cássia Pereira, Aschner, Michael, Orian, Laura, Teixeira Rocha, João Batista

“…The COVID‐19 pandemic caused by the SARS‐CoV‐2 has mobilized scientific attention in search of a treatment. The cysteine‐proteases, main protease (Mpro) and…”
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In vivo treatment with diphenyl ditelluride induces neurodegeneration in striatum of young rats: Implications of MAPK and Akt pathways by Heimfarth, Luana, Loureiro, Samanta Oliveira, Dutra, Márcio Ferreira, Andrade, Cláudia, Pettenuzzo, Letícia, Guma, Fátima T. Costa Rodrigues, Gonçalves, Carlos Alberto Saraiva, da Rocha, João Batista Teixeira, Pessoa-Pureur, Regina

“…In the present report 15day-old Wistar rats were injected with 0.3μmol of diphenyl ditelluride (PhTe)2/kg body weight and parameters of neurodegeneration were…”
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The Thiol-Modifier Effects of Organoselenium Compounds and Their Cytoprotective Actions in Neuronal Cells by Galant, Letícia Selinger, Rafique, Jamal, Braga, Antônio Luiz, Braga, Felipe Camargo, Saba, Sumbal, Radi, Rafael, da Rocha, João Batista Teixeira, Santi, Claudio, Monsalve, Maria, Farina, Marcelo, de Bem, Andreza Fabro

“…Most pharmacological studies concerning the beneficial effects of organoselenium compounds have focused on their ability to mimic glutathione peroxidase (GPx)…”
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Effects of chlorogenic acid, caffeine, and coffee on behavioral and biochemical parameters of diabetic rats by Stefanello, Naiara, Schmatz, Roberta, Pereira, Luciane Belmonte, Rubin, Maribel A., da Rocha, João Batista Teixeira, Facco, Graziela, Pereira, Maria Ester, Mazzanti, Cinthia Melazzo de Andrade, Passamonti, Sabina, Rodrigues, Marília Valvassori, Carvalho, Fabiano Barbosa, da Rosa, Michelle Melgarejo, Gutierres, Jessie Martins, Cardoso, Andréia Machado, Morsch, Vera Maria, Schetinger, Maria Rosa Chitolina

“…Diabetes mellitus (DM) is associated with brain alterations that may contribute to cognitive dysfunctions. Chlorogenic acid (CGA) and caffeine (CA), abundant…”
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Cross-Talk among Intracellular Signaling Pathways Mediates the Diphenyl Ditelluride Actions on the Hippocampal Cytoskeleton of Young Rats by Heimfarth, Luana, Loureiro, Samanta Oliveira, Reis, Karina Pires, de Lima, Bárbara Ortiz, Zamboni, Fernanda, Gandolfi, Talita, Narvaes, Rodrigo, da Rocha, João Batista Teixeira, Pessoa-Pureur, Regina

“…In the present report, we showed that diphenyl ditelluride (PhTe)2 induced in vitro hyperphosphorylation of glial fibrillary acidic protein (GFAP), vimentin…”
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Metals, oxidative stress and neurodegeneration: A focus on iron, manganese and mercury by Farina, Marcelo, Avila, Daiana Silva, da Rocha, João Batista Teixeira, Aschner, Michael

“…► Oxidative stress (OS), particularly in mitochondria, is a common feature of iron (Fe), Mn and Hg toxicity. ► The primary molecular targets triggering of OS…”
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