Search Results - "Batista, Isabel"
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Plant Kunitz Inhibitors and Their Interaction with Proteases: Current and Potential Pharmacological Targets
Published in International journal of molecular sciences (25-04-2022)“…The action of proteases can be controlled by several mechanisms, including regulation through gene expression; post-translational modifications, such as…”
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Crystal structures of a plant trypsin inhibitor from Enterolobium contortisiliquum (EcTI) and of its complex with bovine trypsin
Published in PloS one (23-04-2013)“…A serine protease inhibitor from Enterolobium contortisiliquum (EcTI) belongs to the Kunitz family of plant inhibitors, common in plant seeds. It was shown…”
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3
Snake and arthropod venoms: Search for inflammatory activity in human cells involved in joint diseases
Published in Toxicon (Oxford) (01-02-2024)“…Most anti-inflammatory drugs currently adopted to treat chronic inflammatory joint diseases can alleviate symptoms but they do not lead to remission…”
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4
Longipin: An Amyloid Antimicrobial Peptide from the Harvestman Acutisoma longipes (Arachnida: Opiliones) with Preferential Affinity for Anionic Vesicles
Published in PloS one (20-12-2016)“…In contrast to vertebrate immune systems, invertebrates lack an adaptive response and rely solely on innate immunity in which antimicrobial peptides (AMPs)…”
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5
Common mental disorders and socioeconomic status in adolescents of ERICA
Published in Revista de saúde pública (01-01-2020)“…Adolescence is a stage of great social, family and emotional demands, and the literature has related common mental disorder (CMD) with poor living conditions…”
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A new tick Kunitz type inhibitor, Amblyomin-X, induces tumor cell death by modulating genes related to the cell cycle and targeting the ubiquitin-proteasome system
Published in Toxicon (Oxford) (15-12-2010)“…The aim of this study was to evaluate the anti-tumor activity of Amblyomin-X, a serine protease Kunitz-type inhibitor. Amblyomin-X induced tumor mass…”
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Exploring Chromosomal Polymorphism and Evolutionary Implications in Rineloricaria lanceolata (Günther, 1868) (Siluriformes: Loricariidae): Insights from Meiotic Behavior and Phylogenetic Analysis
Published in Biology (Basel, Switzerland) (01-09-2024)“…Chromosomal polymorphism is a significant aspect of population genetics, influencing the adaptation and evolution of species. In , a Neotropical fish species,…”
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Lonomia obliqua Envenoming and Innovative Research
Published in Toxins (23-11-2021)“…As a tribute to Butantan Institute in its 120th anniversary, this review describes some of the scientific research efforts carried out in the study of…”
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9
Bothrops moojeni Venom and Its Components Strongly Affect Osteoclasts' Maturation and Protein Patterns
Published in Toxins (30-06-2021)“…Osteoclasts (OCs) are important for bone maintenance, calcium balance, and tissue regeneration regulation and are involved in different inflammatory diseases…”
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10
Dendropsophin 1, a novel antimicrobial peptide from the skin secretion of the endemic Colombian frog Dendropsophus columbianus
Published in Natural product research (01-06-2018)“…In efforts to find new antimicrobial peptides (AMPs), we studied the skin secretion of the endemic Colombian frog Dendropsophus columbianus belonging to a…”
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11
Characterization of a new muscarinic toxin from the venom of the Brazilian coral snake Micrurus lemniscatus in rat hippocampus
Published in Life sciences (1973) (19-12-2011)“…We have isolated a new muscarinic protein (MT-Mlα) from the venom of the Brazilian coral snake Micrurus lemniscatus. This small protein, which had a molecular…”
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Aggregation of cardiovascular risk factors: alcohol, smoking, excess weight, and short sleep duration in adolescents in the ERICA study
Published in Cadernos de saúde pública (2019)“…This study aimed to analyze the aggregation of alcohol consumption, smoking, excess weight, and short sleep in Brazilian adolescents. This was a…”
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13
Effects of Mlx-8, a phospholipase A2 from Brazilian coralsnake Micrurus lemniscatus venom, on muscarinic acetylcholine receptors in rat hippocampus
Published in The journal of venomous animals and toxins including tropical diseases (2020)“…Abstract Background: Here, we described the presence of a neurotoxin with phospholipase A2 activity isolated from Micrurus lemniscatus venom (Mlx-8) with…”
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14
Expressed sequence tags (ESTs) from the salivary glands of the tick Amblyomma cajennense (Acari: Ixodidae)
Published in Toxicon (Oxford) (01-04-2008)“…The neotropical tick Amblyomma cajennense is a significant pest to domestic animals, the most frequently human-biting tick in South America and the main vector…”
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15
The phytoactive constituents of Eugenia selloi B.D. Jacks (pitangatuba): Toxicity and elucidation of their anti-inflammatory mechanism(s) of action
Published in Food chemistry. Molecular sciences (30-07-2022)“…•Purified subfraction from Eugenia selloi fruit, showed anti-inflammatory activity.•It were identified isomers of quercetrin, vanillic acid, and coumaric…”
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Evidence of an Antimicrobial Peptide Signature Encrypted in HECT E3 Ubiquitin Ligases
Published in Frontiers in immunology (09-01-2017)“…The ubiquitin-proteasome pathway (UPP) is a hallmark of the eukaryotic cell. In jawed vertebrates, it has been co-opted by the adaptive immune system, where…”
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17
Culturing Chaetoceros muelleri using simplified media with different N sources: effects on production and lipid content
Published in European journal of phycology (01-01-2015)“…Land-based bivalve aquaculture depends on large-scale cultures of live microalgae for food. The intensity of large-scale microalgal production is important for…”
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Polytraumatization, defense mechanisms, PTSD and complex PTSD in Indian adolescents: a mediation model
Published in BMC Psychology (24-11-2023)“…Background Adolescence is recognized as a particularly susceptible developmental period for experiencing multiple types of Adverse Childhood Experiences (ACE),…”
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Lopap, a prothrombin activator from Lonomia obliqua belonging to the lipocalin family: recombinant production, biochemical characterization and structure-function insights
Published in Biochemical journal (01-09-2006)“…Using a cDNA library made from Lonomia obliqua caterpillar bristles, we identified a transcript with a 603 bp open reading frame. The deduced protein…”
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Agregação dos fatores de risco cardiovascular: álcool, fumo, excesso de peso e sono de curta duração em adolescentes do estudo ERICA
Published in Cadernos de saúde pública (2019)“…Resumo: O objetivo foi analisar a agregação do consumo de álcool, tabaco, excesso de peso e sono curto em adolescentes brasileiros. Trata-se de estudo…”
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