Search Results - "Batista, Denise G. J."
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Phenotypic Evaluation of Nucleoside Analogues against Trypanosoma cruzi Infection: In Vitro and In Vivo Approaches
Published in Molecules (Basel, Switzerland) (21-11-2022)“…Chagas disease, caused by Trypanosoma cruzi (T. cruzi), is a serious public health problem. Current treatment is restricted to two drugs, benznidazole and…”
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In Vitro , In Silico , and In Vivo Analyses of Novel Aromatic Amidines against Trypanosoma cruzi
Published in Antimicrobial agents and chemotherapy (01-02-2018)“…Five bis-arylimidamides were assayed as anti- agents by , , and approaches. None were considered to be pan-assay interference compounds. They had a favorable…”
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Experimental chemotherapy for Chagas disease: 15 years of research contributions from in vivo and in vitro studies
Published in Memórias do Instituto Oswaldo Cruz (01-07-2009)“…Chagas disease, which is caused by the intracellular parasite Trypanosoma cruzi , is a neglected illness with 12-14 million reported cases in endemic…”
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Experimental Chemotherapy for Chagas Disease: A Morphological, Biochemical, and Proteomic Overview of Potential Trypanosoma cruzi Targets of Amidines Derivatives and Naphthoquinones
Published in Molecular Biology International (01-01-2011)“…Chagas disease (CD), caused by Trypanosoma cruzi, affects approximately eight million individuals in Latin America and is emerging in nonendemic areas due to…”
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Trypanosoma cruzi Modulates the Expression of Rabs and Alters the Endocytosis in Mouse Cardiomyocytes In Vitro
Published in The journal of histochemistry and cytochemistry (01-06-2006)“…Chagas disease is an incurable illness caused by the protozoan Trypanosoma cruzi. Cardiomyocytes represent important targets for the parasite infection and…”
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Phenotypic Evaluation of Nucleoside Analogues against ITrypanosoma cruzi/I Infection: In Vitro and In Vivo Approaches
Published in Molecules (Basel, Switzerland) (01-11-2022)“…Chagas disease, caused by Trypanosoma cruzi (T. cruzi), is a serious public health problem. Current treatment is restricted to two drugs, benznidazole and…”
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Copper(II) Nitroaromatic Schiff Base Complexes: Synthesis, Biological Activity and Their Interaction with DNA and Albumins
Published in Journal of the Brazilian Chemical Society (01-01-2017)“…Copper(II) complexes of the Schiff base ligands 2-((5-nitrofuran-2-yl)methyleneamino)phenol (HL1) and 2-(4-nitrobenzylideneamino)phenol (HL2) were prepared and…”
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Norfloxacin and N-Donor Mixed-Ligand Copper(II) Complexes: Synthesis, Albumin Interaction, and Anti-Trypanosoma cruzi Activity
Published in Bioinorganic Chemistry and Applications (01-01-2016)“…Copper(II) complexes with the first-generation quinolone antibacterial agent norfloxacin containing a nitrogen donor heterocyclic ligand 2,2′-bipyridine (bipy)…”
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Co(II), Mn(II) and Cu(II) complexes of fluoroquinolones: Synthesis, spectroscopical studies and biological evaluation against Trypanosoma cruzi
Published in Polyhedron (14-06-2011)“…Activity of SPAR, NOR, Mn-SPAR, Co-SPAR, Mn-NOR, Co-NOR, Cu-phen-SPAR and Cu-phen-NOR, CuCl 2 upon bloodstream and intracellular forms of T. cruzi in vitro…”
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